Find 4 Star Hotels in Mytilene from $83

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Mytilene 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mytilene.
Elysion Hotel

Elysion Hotel

Neapoli, Mytilene, Lesvos, Lesvos Island
The price is $145 per night from May 3 to May 4
$145
$169 total
includes taxes & fees
May 3 - May 4
9/10 Wonderful! (37 reviews)
Still don't see what you're looking for?
See all properties in Mytilene.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The preparation of any trip kicks off with deciding on a destination. Mytilene has been a popular option with guests because it offers so much to do. However, "location, location, location" applies to more than just what city where your plane lands. When you want a journey that is amazing from start to finish, you need the perfect place to stay.

Accommodations as Beautiful as the City

Mytilene saw its fair share of visitors in the last year. Our review section contains reviews that will assist you in narrowing down your pick. The resorts found here aim to make your stay as pleasant as your days and evenings out in Mytilene. These hotels aim to make their grounds and facilities hospitable during your visit. You will never have to go far for a delicious meal, a refreshing spa treatment, or to sustain your exercise routine.

Rooms have been designed to keep you as comfortable as possible, with amenities like in-room tea or coffee, specially designed bathroom products, and, premium bedding. So, sit back and relax. Moreover, if you find yourself in need of something further, you can rest easy the staff will try their hardest to ensure you remain happy during your time. These properties are so nice that you'll regret the day you have to fly back home.

Reserve a 4-Star Hotel in Mytilene Today!

A trip to Mytilene should be one where you won't have to worry about the little things. Expedia will get inexpensive rates on world-class accommodations to take your getaway to the next level.

Frequently asked questions

What are the best 4-star hotels in Mytilene?
Look forward to 4-star hotel comfort at Theofilos Paradise Boutique Hotel. Ranked highly by many of our guests, it offers concierge services and treatment rooms. Also check out Porto Lesvos. Concierge services and complimentary breakfast make this escape another leading pick in Mytilene.
How much does it cost to stay in a 4-star hotel in Mytilene?
To lock in a 4-star hotel in Mytilene that matches your budget, make use of Expedia’s sort and search filters. Check out what’s available during your getaway dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from $122

What's the difference between 5-star and 4-star hotels in Mytilene?
Offering a welcoming traveler experience and upmarket surroundings, 4-star hotels are a great option for your Mytilene vacation. These kinds of accommodations generally feature lots of useful amenities that make it a breeze to kick back and relax — think 24-hour room service, restaurants and pools. Or enjoy even more lavishness at a 5-star hotel designed to pamper with high-end perks and amenities. Full-service health clubs, oversized bathrooms and world-class dining are typically featured at these plush retreats.
Does Mytilene have any 4-star all-inclusive resorts?
One of the quickest ways to look for the perfect Mytilene getaway is to click on our “All inclusive” filter tool. You can also find other excellent 4-star options such as Porto Lesvos and Theofilos Paradise Boutique Hotel. They both feature outstanding service and a wealth of amenities for your relaxation and comfort.
Are there any 4-star casino hotels in Mytilene?
Use our convenient filters to refine your Mytilene search by star rating, amenities and more. Whether you’re after the complete casino resort experience or just want to try your luck while living it up in 4-star style, you’re sure to find a place that strikes the perfect balance between entertainment and relaxation.

Recent reviews of Mytilene hotels
Expedia verified reviews

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

5/5 Excellent
"Verry nice place to stay."
A verified traveler stayed at Theofilos Paradise Boutique Hotel
Posted 7 months ago
Theofilos Paradise Boutique Hotel