Find 4 Star Hotels in St. Charles, MO from $110
Most hotels are fully refundable. Because flexibility matters.
Save 10% or more on over 100,000 hotels worldwide as a One Key member.
Search over 2.9 million properties and 550 airlines worldwide.
Compare St. Charles 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Explore similar 5-star hotels
The Ritz-Carlton, St. Louis
The get-go of any well-deserved trip gets started with selecting a splendid destination. St. Charles has become a popular destination with guests because of everything it offers. However, "location, location, location" applies to more than just your destination. When you want a trip that is amazing from start to finish, you need the ideal hotel.
Accommodations as Gorgeous as the City
St. Charles saw its fair share of visitors this past year. Expedia's review section contains comments to help you decide which hotel is the perfect fit for your vacation. When you reserve a 4-star room you can breathe easy knowing that these properties aim to meet your every need. You'll never have to search long for a tasty breakfast, to sustain your workout routine, or a refreshing spa treatment during your stay, thanks to all these hotels offer. They aim to make the grounds and facilities welcoming from the minute you step onto the property and with every step across their floors. St. Charles has several wonderful hotels that create the absolute perfect vacation.
Rooms have been fashioned to keep you as comfortable as possible, with amenities like in-room coffee or tea, designer bathroom products, and, premium bedding. So, sit back and unwind. Moreover, if you find yourself in need of something more, you can trust the staff will work their best to ensure you continue to be satisfied during your stay. These hotels are so nice that you'll regret the day you have to check-out.
Reserve a 4-Star Hotel in St. Charles Today!
Your getaway to St. Charles should be a break from your daily routine. Make sure to book soon. With so few hotels, and a lot of people wanting to vacation in St. Charles, you may miss the chance to snag the perfect place.
Frequently asked questions
Recent reviews of St. Charles hotelsExpedia verified reviews
St. Charles Hotels by Star Rating
Hotels in St. Charles Neighborhoods
Stay near popular St. Charles attractions
- Ameristar Casino St. Charles
- St Charles Convention Center
- Lindenwood University
- Historic Main Street
- Family Arena
- Fast Lane Classic Cars
- Katy Trail
- Lewis & Clark Boathouse and Nature Center
- Missouri Bluffs Golf Course
- First Missouri State Capitol Historic Site
- Weldon Spring Site Interpretive Center
- Jaycee Park
- St. Louis Union Station
- Busch Stadium
- St. Louis Zoo
- Gateway Arch
- Six Flags St. Louis
- Washington University in St. Louis
- Enterprise Center
- Forest Park
More Hotel Options in St. Charles
- Business Hotels (17)
- Casinos (17)
- Cheap Hotels (9)
- Family Hotels (17)
- Golf Hotels (4)
- Historic Hotels (17)
- Hotel Wedding Venues (8)
- Hotel with a Concierge (4)
- Hotels & Resorts for Couples (7)
- Hotels with Air Conditioning (17)
- Hotels with Bars (11)
- Hotels with Connecting Rooms (6)
- Hotels with Free Breakfast (13)
- Hotels with Free Parking (17)
- Hotels with Free Wifi (17)
- Hotels with Hot Tubs (8)
- Hotels with Laundry Facilities (15)
- Hotels with Restaurants (17)
- Hotels with Room Service (3)
- Hotels with Suites (5)
- Hotels with a Gym (13)
- Hotels with a Pool (15)
- Hotels with a View (3)
- Hotels with an Indoor Pool (13)
- Hotels with an Outdoor Pool (15)
- Hotels with smoking rooms (3)
- Luxury Hotels (6)
- Non-Smoking Hotels (10)
- Pet-friendly Hotels (9)
- Quiet Resorts & Hotels (3)
- Resorts & Hotels with Spas (6)
- Romantic Hotels (7)
More Popular Hotels in St. Louis
- Drury Plaza Hotel St. Louis at the Arch
- Hollywood Casino & Hotel St. Louis
- Best Western St. Louis-Kirkwood Route 66
- The Last Hotel
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Drury Inn & Suites St. Louis Union Station
- Renaissance St. Louis Airport Hotel
- 21C Museum Hotel St Louis
- Casino Queen Hotel
- Hilton St. Louis at the Ballpark
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Angad Arts Hotel
- Le Méridien St. Louis Clayton
- Pear Tree Inn St. Louis Near Union Station
- Pear Tree Inn St. Louis Airport
- Moonrise Hotel
- Live by Loews - St.Louis
- Wingate by Wyndham St. Louis Airport
- Forest Park Hotel by MDR
- La Quinta Inn & Suites by Wyndham St. Louis Westport