Find 5 Star Hotels in Downtown St. Louis, MO from $149

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Compare Downtown St. Louis 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Downtown St. Louis.
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis, MO
The price is $149 per night from May 11 to May 12
$149
$176 total
includes taxes & fees
May 11 - May 12
8.2/10 Very Good! (2,974 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Downtown St. Louis?
Experience top-class amenities and refined service at Four Seasons Hotel St Louis. Located around the St. Louis neighborhood of Downtown St. Louis, this 5-star hotel is a leading choice based on reviews by Expedia guests.
How much does it cost to stay in a 5-star hotel in Downtown St. Louis?
How much you pay for a 5-star hotel in Downtown St. Louis can vary depending on when you want to travel and how long you plan to be away, among several factors. Use our price per night filter and other search tools to land the best rate on an indulgent stay.

  • Search for the lowest price per night from $149

What makes a hotel 5 stars in Downtown St. Louis?
In Downtown St. Louis, a hotel needs to provide a certain amount of upscale conveniences to earn a 5-star rating. These can include on-site gyms, spas and saunas, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their guest-focused standard of service. You can look forward to things like in-room massages, nightly turn-down services and concierge services. Some may also offer additional touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Downtown St. Louis?
Our filter tool is the quickest way to narrow down what you want. Select “5-star” and “All inclusive” to see the most luxurious resorts in Downtown St. Louis where your meals, room, entertainment and activities are included in the upfront price. At these escapes, your vacation is pure leisure from the moment you check in.
What are the top 5-star spa hotels in Downtown St. Louis?
Spend your next vacation being pampered and indulged at Four Seasons Hotel St Louis. This 5-star spa property in the Downtown St. Louis area offers a range of treatments and experiences that inspire rejuvenation, relaxation and self-care.
Are there any 5-star vacation rentals in Downtown St. Louis?
Our site doesn’t have any 5-star vacation rentals in Downtown St. Louis. However, you will still find a few top-rated retreats where the only thing on your agenda will be to kick back and enjoy yourself. View what’s available by searching through our vacation rentals in Downtown St. Louis.

Recent reviews of Downtown St. Louis hotels
Expedia verified reviews

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5/5 Excellent
"The Four Seasons is a very high end quality hotel. It has great rooms with great beds. The staff was very welcoming and attended to my needs. The only thing I did not like was the noise in the middle of the night from the sirens of police cars and ambulances. It was a bit of a nuances. The place was very clean. I was there for a gala and it was very well put together. The food was very good. The place is very clean. We also visited the Gordon Ramsey restaurant and checked out the other amenities they had. Great hotel to stay at. It was a stay cation for me. "
A verified traveler stayed at Four Seasons Hotel St Louis
Posted 2 days ago
Four Seasons Hotel St Louis