Find 5 Star Hotels in Syracuse from $109

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Compare Syracuse 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You enjoy the finer things in life, both at home and on vacation. Treat your every whim on your upcoming break. There's no reason to delay a getaway to Syracuse any longer. You'll join the multitudes of vacationers who have made Syracuse so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve an outstanding getaway. Book one of Expedia's luxurious 5-star hotels in Syracuse and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Syracuse

You'll have a wonderful time at one of these 5-star hotels. Highly-rated eateries, concierges, and in-room spa sessions are all at the ready. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? A deep-tissue massage to help your cares fall away? A concierge to help you plan every detail of your day? Fluffy down pillows, lip-smacking main courses, and even space for your family pet in some cases...these hotels are one-of-a-kind.

Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Syracuse are the perfect place to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Make Your Escape

The results are in, and Syracuse 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Select one of Expedia's Syracuse 5-star hotels today and relax in luxe surroundings tomorrow.

Frequently asked questions

What are the best 5-star hotels in Syracuse?
According to Expedia traveler reviews, Grand Hotel Ortigia Siracusa, Ortea Palace Luxury Hotel and Grand Hotel Des Ètrangers are among the most popular 5-star hotels in Syracuse. Providing first-rate amenities and unparalleled service, you’ll enjoy an opulent and memorable stay.
How much does it cost to stay in a 5-star hotel in Syracuse?
How much you pay for a 5-star hotel in Syracuse can vary based on the time of year you travel and how long you plan to be away, among a range of factors. Take advantage of our price per night filter and other search tools to find the best rate on a high-end getaway.

  • Search for the lowest price per night right now $109

What makes a hotel 5 stars in Syracuse?
In Syracuse, a hotel needs to offer a specific amount of high-end conveniences to earn a 5-star rating. These may include on-site gyms, gourmet restaurants, saunas and spas, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their guest-focused standard of service. You can expect things like in-room massages, concierge services and nightly turn-down services. Some may also offer additional touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Syracuse?
Use Expedia’s filter tool to find a luxurious escape in Syracuse where everything you need is included. After your initial search, narrow your results for accommodations that have 5 stars and are listed as “All inclusive.” The first thing to look forward to at these stays? Relaxation and enjoyment.
What are the top 5-star spa hotels in Syracuse?
Syracuse boasts a selection of 5-star spa escapes that offer experiences designed to rejuvenate the body, mind and soul. Book a stay at Minareto, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Ortigia Siracusa and focus on your self-care and well-being.
Are there any 5-star vacation rentals in Syracuse?
There are no 5-star vacation rentals in Syracuse, but there are a range of other highly rated options worth checking out. Browse our vacation rentals in Syracuse to find the perfect place for your getaway.
Are there any 5-star hotels in downtown Syracuse?
Book your stay at Grand Hotel Ortigia Siracusa and enjoy being near the sights and action of downtown Syracuse.

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