This hotel is reasonably priced for Athens, and the location of the hotel itself feels rather safe: but I would highly caution anyone against walking from this hotel to the center of Athens - prostitution, druggies, and trash along the 20 minute route, and definitely didn't feel safe on the streets there.
The hotel itself if fine: room was as expected, though we were told to leave the key at the front desk when we left: which seemed a bit risky given the general atmosphere of the area: front desk was a bit rude when we arrived: demanding that we pay the .50 euro 'tourist tax' immediately upon arrival even though we didn't have any change on us.
Might stay there again in a pinch, but probably would find somewhere else if possible.