I have recently begun doing city breaks with the family, I am happy with a hotel that is clean, safe and well-priced as ultimately it is somewhere to sleep when you get back from a long day of exploring.
This hotel ticked all the boxes, the staff were friendly, the room was spacious and easily big enough for the 4 of us (family of 4 with 2 children aged 13 and 11). There was plenty of shops, bars and food outlets nearby and a bus stop right outside from where you could get a very frequent bus to Berlin Central station (number 245) in about 10 minutes.
The only negative I had was our last night was a Friday and we didn't realise the staff had put us directly above a pub/club until that night when the music went on until the early hours.
I recommend asking to avoid this part of the hotel at weekends. Otherwise, a very nice base for which to explore at amazing value.