Experience the city scene with reservations at a hotel in Central San Diego.
Shopping in Horton Plaza, thriving nightlife in the Gaslamp Quarter, and exploring museums in Balboa Park are all at your fingertips when you stay at one of the central San Diego hotels.
These areas in SoCal will welcome you like a local. Feast on fresh homemade pasta in Little Italy, check out the Padres Petco Park stadium in East Village, or stroll along the harbor and check out the Star of India within easy access of your hotel. No matter what part of Central San Diego you wish to explore, Expedia has the right accommodations for you. From family-friendly suites with pool access for the kiddos to romantic hotels to spend a getaway with your sweetheart, you’ll find it all here.
Score the lowest rates on hotels in Central San Diego when you browse our selection. You’ll also find the hottest discounts on Downtown San Diego hotels, so you can put your leftover money toward spending a day at the San Diego Zoo or seeing a show at the Civic Theater. Whether you’re traveling alone, with your partner, or with the whole family in tow, Expedia has the perfect hotel for you. Don’t settle for lackluster lodgings, and instead choose the hotel that fits you and your getaway right here on Expedia.