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Central West End St. Louis Vacation Packages

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

The Central West End is the ideal place to enjoy characteristic St. Louis atmosphere. Fill your days with the sights and sounds of this charming neighborhood, where grand historic buildings meet modern stores, restaurants and attractions. Stop at some of the fascinating local museums while you are here. 

Find some of St. Louis’ best-preserved historic streets in the Central West End. Much of its architecture dates from the late 19th and early 20th centuries. In 1904, the city held the St. Louis World’s Fair, turning this area into a favorite among chic, wealthy citizens. Famous people who once walked these streets include literary greats Tennessee Williams, T.S. Eliot, Sara Teasdale and William S. Burroughs. 

Discovering eclectic stores and cafés filling the Central West End is a highlight of any trip. Many of St. Louis’ tourist sights are concentrated here too. Make sure you stop at the Cathedral Basilica of Saint Louis, a stunning building with ornate paintings reaching all the way up to its high ceiling. Admire the detail of the extensive mosaic collection in the basement museum.

Continue your spiritual journey at the Museum of Contemporary Religious Art. The collections here draw items from across many different faiths and nations. See how artists working today are bringing new perspectives to the age-old theme of faith.

Another novel attraction is the World Chess Hall of Fame, which is home to the world’s largest chess piece. Look for this impressive object, which stands outside, as you approach. Inside, learn about World Chess champions and see their stories told through medals, trophies and other personal items.

The Central West End is easy to find due to its location in the heart of the city. Go on a sunny day to enjoy Forest Park, a peaceful green space that is the pride of the area. If it starts to rain, step into the St. Louis Art Museum or the Missouri History Museum, both housed in the park.

Booking a beautiful hotel is crucial for a truly memorable vacation. Compare the best selection of Central West End accommodation options on Expedia's easy-to-use hotels guide.

The Four Seasons Hotel St Louis, at 999 North Second Street, and The Ritz-Carlton, St. Louis, at 100 Carondelet Plaza are two of the higher-end lodgings in Central West End. Book a room at either and you'll be sure to have the best amenities in town. If those don't grab you, be sure to check out the Days Inn Downtown St. Louis, at 2810 N 9th St, and the Americas Best Value Inn St. Louis/Downtown, at 1100 N 3rd St, two of the cheaper options in town.


Top Hotel Deals

See all 239 Hotels in Central West End
$139
The Parkway Hotel

The Parkway Hotel

4550 Forest Park Ave, St. Louis
4.2
of 5, from 473 reviews
3.0 out of 5.0

Located in Central West End, this hotel is within a 15-minute walk of Barnes Jewish Hospital, World Chess Hall of Fame, and Cathedral Basilica of St. Louis. St. Louis Science Center and The Muny Theater are also within 2 mi (3 km).

$199
The Chase Park Plaza Royal Sonesta St. Louis

The Chase Park Plaza Royal Sonesta St. Louis

212 N Kingshighway, St. Louis
4.4
of 5, from 619 reviews
4.5 out of 5.0

Located in the fashionable Central West End of St. Louis and close to Washington University and St. Louis University, this hotel is surrounded by shops, restaurants, mansions, and Forest Park. It's also 4 blocks from Barnes Hospital and 1 mile from museums and the zoo.

$103
Holiday Inn Express St Louis - Central West End

Holiday Inn Express St Louis - Central West End

4630 Lindell, St. Louis
3.5
of 5, from 90 reviews
3.0 out of 5.0

Located in Central West End, this hotel is within a 10-minute walk of World Chess Hall of Fame and Cathedral Basilica of St. Louis. St. Louis Zoo and St. Louis Art Museum are also within 3 mi (5 km).

$135
Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park

920 S. Taylor Avenue, St. Louis
4.5
of 5, from 52 reviews
2.5 out of 5.0

Located in Central West End, this hotel is within 1 mi (2 km) of Barnes Jewish Hospital and Cathedral Basilica of St. Louis. Missouri Botanical Gardens and Arboretum and St. Louis Zoo are also within 3 mi (5 km).

$119
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis
4.3
of 5, from 1,639 reviews
4.0 out of 5.0

This 18-story Hyatt Regency hotel is 4 blocks from Busch Stadium and within a mile of Edward Jones Dome, Scottrade Center, Laclede's Landing, and the America's Center.

Super 8 - Fenton/St. Louis Area

Super 8 - Fenton/St. Louis Area

650 S Highway Dr, Fenton
2.0
of 5, from 112 reviews
2.0 out of 5.0

Situated in Fenton, this motel is 1.3 mi (2.1 km) from LIFECHURCH and within 6 mi (10 km) of Laumeier Sculpture Park and Powder Valley Conservation Nature Center. Magic House - St. Louis Children's Museum and Frank Lloyd Wright House in Ebsworth Park are also within 6 mi (10 km).

Econo Inn

Econo Inn

5307 Bunkum Rd, Washington Park
2.4
of 5, from 13 reviews
2.0 out of 5.0

Situated in Washington Park, this motel is within 6 mi (10 km) of Katherine Dunham Museum, Dome at America’s Center, and Cahokia Mounds State Historic Site. Gateway International Raceway and Malcolm Martin Memorial Park are also within 6 mi (10 km).

$93
City Place St. Louis - Downtown Hotel

City Place St. Louis - Downtown Hotel

200 North 4th Street, St. Louis
3.2
of 5, from 1,246 reviews
3.5 out of 5.0

This 29-story St. Louis hotel is 4 blocks from Busch Stadium, 6 blocks from the Edward Jones Dome and the Lumiere Place Casino, and less than 1 mile from Scottrade Center, Laclede's Landing, and America's Center.

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