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Downtown Syracuse Vacation Travel Guide

Accommodation in Downtown Syracuse

Hotel options in Downtown Syracuse can be quite sparse. Check out the latest information, listings and deals on Expedia's comprehensive Downtown Syracuse hotels guide.

It’s easy to book the getaway of your dreams when you search through our selection of Downtown Syracuse vacations. Our goal? To create the perfect trip for you by providing the largest selection of vacation packages. Confidently book your getaway thanks to our trustworthy recommendations and verified consumer reviews from travelers just like you. Personalize your Downtown Syracuse package with our myriad of hotel rooms and flight tickets, which help to create a vacation specifically for you. Simply sort through our selection and pick and choose the elements that best suit your preferences and price range.

Because we offer the best rates, you can book your travel reservations knowing you won’t find lower prices elsewhere. These discounts are so great, you’ll feel like you gained the title of the ultimate bargain hunter with our Downtown Syracuse vacation package deals. Whether you’re looking to book multiple flights, stay at the fanciest hotel, or explore the hottest local attractions, you’ll find discounted travel arrangements within your budget right here. You shouldn’t have a care in the world when you go on vacation, so our discounts allow you to rest easy without giving your bank account a second thought. Save money on your vacation today and revel in your much-deserved getaway tomorrow.


Top Hotel Deals

See all 92 Hotels in Downtown Syracuse
$119
Aloft Syracuse Inner Harbor

Aloft Syracuse Inner Harbor

310 West Kirkpatrick Street, Syracuse
4.4
of 5, from 61 reviews
3.0 out of 5.0

Situated on a lake, this hotel is within 1 mi (2 km) of Museum of International Masks and Puppets and Museum of Science and Technology. Erie Canal Museum and Everson Museum of Art are also within 2 mi (3 km).

$143
Hotel Skyler

Hotel Skyler

601 South Crouse, Syracuse
4.5
of 5, from 366 reviews
3.0 out of 5.0

Located in Downtown Syracuse, this hotel is within a 10-minute walk of SUNY Upstate Medical University and Syracuse University. Carrier Dome and Everson Museum of Art are also within 15 minutes.

$169
Jefferson Clinton Hotel

Jefferson Clinton Hotel

416 S Clinton St, Syracuse
4.5
of 5, from 145 reviews
3.0 out of 5.0

Located in Downtown Syracuse, this historic hotel is steps from Armory Square and Museum of Science and Technology. Erie Canal Museum and Everson Museum of Art are also within 15 minutes.

$159
Sheraton Syracuse University Hotel & Conference Center

Sheraton Syracuse University Hotel & Conference Center

801 University Ave, Syracuse
4.2
of 5, from 53 reviews
3.5 out of 5.0

Located in Downtown Syracuse, this hotel is within a 10-minute walk of Crouse Hospital, Syracuse University, and Carrier Dome. OnCenter Complex and Everson Museum of Art are also within 1 mi (2 km).

$159
Genesee Grande Hotel and Suites

Genesee Grande Hotel and Suites

1060 E Genesee St, Syracuse
4.1
of 5, from 337 reviews
3.5 out of 5.0

Set in the quiet neighborhood of University Hill, The Genesee Grande Hotel and Suites is a two-minute drive from Syracuse University and Carrier Dome, and fifteen minutes from the Syracuse airport.

$98
Crowne Plaza Syracuse

Crowne Plaza Syracuse

701 E Genesee Street, Syracuse
3.8
of 5, from 271 reviews
3.5 out of 5.0

Close to 4 major medical centers and the interchange of I-690 and I-81, this Syracuse hotel is less than a mile from the Syracuse University campus and 4 blocks from the OnCenter convention complex.

$129
Parkview Hotel

Parkview Hotel

713 E Genesee St, Syracuse
4.3
of 5, from 565 reviews
3.0 out of 5.0

Located in Downtown Syracuse, this hotel is within a 15-minute walk of Community Folk Art Center, Erie Canal Museum, and Everson Museum of Art. Museum of Science and Technology and Syracuse University are also within 1 mi (2 km).

$134
Marriott Syracuse Downtown

Marriott Syracuse Downtown

100 East Onondaga Street, Syracuse
4.5
of 5, from 43 reviews
4.0 out of 5.0

Located in Downtown Syracuse, this hotel is within a 10-minute walk of Onondaga County War Memorial, Museum of Science and Technology, and Erie Canal Museum. Everson Museum of Art and OnCenter Complex are also within 10 minutes.

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