Find hotels in Main Street Hyannis, MA from $68

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Compare 5,525 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

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Main Street Hyannis Travel Info

Number of reviews
5,291
Accommodation
5,525 hotels
Highest price
$166
Lowest price
$68
Reasons to visit
Cape Codder Water Park, John F. Kennedy Hyannis Museum and Kalmus Beach
Hotels with nearby beaches
395
Hotels with dining
303

Frequently asked questions

Where is the best place for a stay in Main Street Hyannis?

Hyannis Plaza Hotel is one of the top choices for your stay based on our traveler data. This hotel offers a restaurant and an outdoor pool. Other good choices for your trip to the area are Bayside Resort Hotel and Cape Codder Resort and Spa. See all available top hotels, or vacation rentals in Main Street Hyannis.

What are some of the best vacation rentals that Main Street Hyannis has to offer?

Charming Cottage Falmouth Cape Cod : This vacation home rental outside Main Street Hyannis is equipped with a barbecue grill, air-conditioning, and free WiFi to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher, and a stovetop. See all vacation rentals in Main Street Hyannis.

If I need to cancel my hotel reservation in Main Street Hyannis, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Main Street Hyannis.

Where can I learn more about changing or cancelling my trip to Main Street Hyannis?

To access more information about rescheduling or cancelling your trip to Main Street Hyannis, click here.

What's the best accommodation for a budget-friendly stay in Main Street Hyannis?

Based on reviews, Courtyard Resort Hyannis, a VRI resort is a popular 2.5-star hotel for our travelers looking for an economical choice, and features free WiFi and free parking. View all budget hotels in Main Street Hyannis.

What's the best hotel when traveling with kids to Main Street Hyannis?

Comfort Inn Hyannis - Cape Cod is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Hyannis Inn is another good option for your stay with the kids. Attractions like Cape Cod Baseball Hall of Fame and Cape Cod Carousel are also fun for kids of all ages. Find more child-friendly accommodations in Main Street Hyannis.

What's the best place to stay for a romantic vacation to Main Street Hyannis?

Hyannis Plaza Hotel is a favorite hotel for couples, and features premium bedding and slippers. Other good choices for a stay with your sweetheart include Hyannis Inn and Americas Best Value Inn & Suites Hyannis Cape Cod. See all romantic hotels in Main Street Hyannis.

What's the best hotel to stay with easy access to John F. Kennedy Hyannis Museum?

Adjacent to John F. Kennedy Hyannis Museum, Hyannis Travel Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. Other good choices close by include Anchor In Distinctive Waterfront Lodging and SeaCoast Inn.

What about the best place to stay close to Cape Cod Baseball Hall of Fame?

One of the top choices for your stay is Hyannis Travel Inn, located next to Cape Cod Baseball Hall of Fame, and this hotel offers free breakfast and an outdoor pool. Anchor In Distinctive Waterfront Lodging and SeaCoast Inn are two other good choices in the immediate area.

What's the best hotel to stay near the beach in Main Street Hyannis?

Hyannis Plaza Hotel is a top beach hotel with a seasonal outdoor pool and free parking, and it's located close to Keyes Beach. Hyannis Inn is another good option for your stay near the beach. See more stays near the beach in Main Street Hyannis.

What's the best luxury hotel in Main Street Hyannis?

Hyannis Plaza Hotel is a luxury hotel with a seasonal outdoor pool and a bar, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Find more luxury hotels in Main Street Hyannis.

What are some accommodations with pools in Main Street Hyannis?

Hyannis Plaza Hotel: Features free self parking, a seasonal outdoor pool, and flat-screen televisions. Bayside Resort Hotel and Cape Codder Resort and Spa are a couple of other choices that offer an onsite pool. View all hotels with pools in Main Street Hyannis.

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