From Middletown, it's 70 miles (113 kilometers) to the south to San Francisco and 100 miles (161 kilometers) to the southeast to San Jose - Silicon Valley.
Do-it-yourself adventurers will enjoy leaving the tourist trail behind by visiting the other towns, cities and attractions surrounding Middletown. Make sure you make tracks to the Calistoga Spit N' Cycle and Chateau Montelena Winery in Calistoga, approximately 12 miles (19 kilometers) away. Also, you could visit the Redbud Park and Austin Park in Clearlake. It is 14 miles (23 kilometers) away from Middletown.
Approximately 35 miles (56 kilometers) to the south of Middletown is Sonoma, a regional center where you'll find Deloach Vineyards, Mission San Francisco Solano and Sonoma Golf Club. Make sure you don't rush back to Middletown until you've checked out Sonoma's Sonoma Town Hall, Jack London State Historical Park and Sebastiani Theatre.
No break is really complete without a little R&R. Camping is one of the ways they relax here. In this region and shore fishing is another.
For those who intend on arriving and departing by air, keep in mind that the nearest major airport is Sonoma County Airport, 20 miles (32 kilometers) to the southwest of Middletown.