Find Resorts & Hotels with Spas in San Luis Obispo, CA

Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers love the wineries and restaurants in San Luis Obispo. Enjoy the art galleries and beaches during your vacation. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.

Madonna Inn is a top spa hotel featuring a fitness center, tennis courts, a bar, and an outdoor pool. Spend an afternoon at The Spa at Madonna Inn. where you’ll find facials, body scrubs, and Swedish massages and more. Other popular spa hotels in San Luis Obispo include HOTEL CERRO, Autograph Collection and Hotel San Luis Obispo.

Among Expedia’s 224 accommodation options in San Luis Obispo, there are 3 spa hotels.

Enjoy all that San Luis Obispo has to offer and visit Fremont Theater, San Luis Obispo Superior Court, and Bubblegum Alley. If you have extra time while you’re in the area, you might want to see Mission San Luis Obispo de Tolosa and Ah Louis Store.

Spa hotels in San Luis Obispo provide lodging and have a full on-site spa which offers services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.