Northwest Airlines was founded in 1926 when "Northwest" still meant the area surrounding Lake Superior and Lake Michigan: Northwest's first route was between MinneapolisSt. Paul and Chicago. Today, Northwest Airlines is one of the world's largest airlines. Together with its global travel partners, Northwest Airlines serves almost 750 destinations in nearly 120 countries on six continentsso chances are they’re going where you want to go, when you want to go. And when you book your Northwest flight on Expedia, you’ll even get a money-saving Web Fare if one is available for your requested day, time, and destination.