Best Western Inn of Williams

·From: Interstate 40. GATEWAY TO THE GRAND CANYON. The Best Western Inn of Williams is located at Interstate 40 and Exit 161 on the west side of scenic Williams, Arizona. ·From: The north. From the Grand Canyon area on Highway 64, stay on Highway 64 as it becomes Route 66 West. Go through town to the Best Western Inn of Williams. ·From: The east or west. From Interstate 40 take Exit 161, the Best Western Inn of Williams is located on the South side of Interstate 40.