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Compare 1,805 hotels close to 21c Museum Hotel with room rates, reviews, and availability. Most hotels are fully refundable.

The Grady

4.0 star property
9.4 out of 10, Exceptional, (999)
"Lovely hotel at a great location. "
$160 nightly
The price is $188
Jul 27 - Jul 28
Total includes taxes and fees
The Grady

Hotel Distil, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (391)
"Clean, classy with an excellent bar/restaurant!!"
$159 nightly
The price is $187
Aug 10 - Aug 11
Total includes taxes and fees
Hotel Distil, Autograph Collection

Louisville Bourbon Inn

5.0 star property
10.0 out of 10, Exceptional, (16)
"Wonderful experience with Victorian era Decor and fabulous Southern Breakfast. "
$265 nightly
The price is $308
Jul 16 - Jul 17
Total includes taxes and fees
Louisville Bourbon Inn

Market Street Inn

3.5 star property
9.8 out of 10, Exceptional, (112)
"Beautiful historic building that has been done up to luxury status. Very thoughtful things like bottled water and popcorn are available."
$167 nightly
The price is $188
Jul 20 - Jul 21
Total includes taxes and fees
Market Street Inn

DuPont Mansion Bed & Breakfast

3.0 star property
9.8 out of 10, Exceptional, (77)
"Beautiful inn and super friendly staff. Breakfast was delicious!"
$141 nightly
The price is $164
Aug 14 - Aug 15
Total includes taxes and fees
DuPont Mansion Bed & Breakfast

Homewood Suites by Hilton Louisville Downtown, KY

3.0 star property
9.2 out of 10, Wonderful, (1000)
"Good hotel "
$111 nightly
The price is $131
Aug 3 - Aug 4
Total includes taxes and fees
Homewood Suites by Hilton Louisville Downtown, KY

Cambria Hotel Louisville Downtown-Whiskey Row

3.0 star property
9.4 out of 10, Exceptional, (1021)
"Great room and staff The hotel is excellent and will stay there in the future"
$122 nightly
The price is $143
Aug 3 - Aug 4
Total includes taxes and fees
Cambria Hotel Louisville Downtown-Whiskey Row

The Brown Hotel

4.5 star property
9.4 out of 10, Exceptional, (1031)
"Great stay "
$179 nightly
The price is $211
Jul 17 - Jul 18
Total includes taxes and fees
The Brown Hotel

21c Museum Hotel Louisville

4.5 star property
9.2 out of 10, Wonderful, (1000)
"Excellent place to stay. "
$165 nightly
The price is $194
Aug 1 - Aug 2
Total includes taxes and fees
21c Museum Hotel Louisville

Towneplace Suites By Marriott Louisville Downtown

3.0 star property
9.2 out of 10, Wonderful, (416)
"Very clean and excellent location - friendly staff "
$97 nightly
The price is $114
Aug 3 - Aug 4
Total includes taxes and fees
Towneplace Suites By Marriott Louisville Downtown

Stellar Suites

4.5 star property
9.6 out of 10, Exceptional, (99)
"Great spot a must stay"
$159 nightly
The price is $185
Jul 16 - Jul 17
Total includes taxes and fees
Stellar Suites

Tempo By Hilton Louisville Downtown Nulu

3.5 star property
9.4 out of 10, Exceptional, (647)
"wonderful stay"
$127 nightly
The price is $149
Jul 17 - Jul 18
Total includes taxes and fees
Tempo By Hilton Louisville Downtown Nulu

Omni Louisville Hotel

4.0 star property
9.2 out of 10, Wonderful, (1504)
"Fantastic stay."
$159 nightly
The price is $187
Aug 8 - Aug 9
Total includes taxes and fees
Omni Louisville Hotel

Holiday Inn Express & Suites Louisville Downtown by IHG

2.5 star property
8.8 out of 10, Excellent, (1484)
"Great staff, nice and clean hotel. "
$83 nightly
The price is $98
Aug 4 - Aug 5
Total includes taxes and fees
Holiday Inn Express & Suites Louisville Downtown by IHG

Hotel Genevieve part of JdV by Hyatt

4.0 star property
9.2 out of 10, Wonderful, (897)
"Great stay! "
$135 nightly
The price is $159
Jul 20 - Jul 21
Total includes taxes and fees
Hotel Genevieve part of JdV by Hyatt

Moxy Louisville Downtown

3.5 star property
9.0 out of 10, Wonderful, (634)
"Cool property, good restaurant and solid location! "
$111 nightly
The price is $131
Aug 3 - Aug 4
Total includes taxes and fees
Moxy Louisville Downtown

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

4.0 star property
9.0 out of 10, Wonderful, (14)
"Awesome place "
$203 nightly
The price is $239
Jul 31 - Aug 1
Total includes taxes and fees
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

TownePlace Suites by Marriott Louisville North

3.0 star property
9.2 out of 10, Wonderful, (571)
"Nice rooms, friendly staff, Relaxing and great place to rest. Good restaurants too! "
$116 nightly
The price is $131
Aug 7 - Aug 8
Total includes taxes and fees
TownePlace Suites by Marriott Louisville North

AC Hotel Louisville Downtown

3.5 star property
9.2 out of 10, Wonderful, (557)
"Great stay "
$130 nightly
The price is $152
Aug 3 - Aug 4
Total includes taxes and fees
AC Hotel Louisville Downtown

Aloft Louisville Downtown

3.0 star property
9.0 out of 10, Wonderful, (1000)
"Great location on Whiskey Row with friendly staff! Beds are comfortable and restaurant onsite. "
$111 nightly
The price is $131
Aug 3 - Aug 4
Total includes taxes and fees
Aloft Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like around 21c Museum Hotel?

21c Museum Hotel is located in a family-friendly area of Louisville known for its beautiful river views and great live music scene. If you're looking for a convenient place to stay, check out the 247 hotels and other accommodations you'll find within a mile.

What's the best place to stay near 21c Museum Hotel?

Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.

How many hotels will I find close to 21c Museum Hotel?

Expedia has 247 hotels and other accommodations within a mile from 21c Museum Hotel.

If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals near 21c Museum Hotel.

Where can I learn more about changing or cancelling my trip in the area near 21c Museum Hotel?

For additional details about updating your stay near 21c Museum Hotel or cancelling it, click here.

What can I see and do near 21c Museum Hotel?

You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center, or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can watch performances at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse if you're interested in local theater.