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Featured Santee 2 Star Hotels

See all 50 Hotels in Santee
Baymont Inn & Suites Orangeburg North

Baymont Inn & Suites Orangeburg North

3583 Saint Matthews Rd, Orangeburg
2.5 out of 5.0
3.9 out of 5 (492 reviews)
Great valueClean rooms, courteous staff, close to restaurant. Comfortable bed. Only down side is towels are thin and rough as sandpaper, but overall you get a lot for the price.
  Nov 20, 2017

$75

$75
Country Inn & Suites By Carlson, Orangeburg, SC

Country Inn & Suites By Carlson, Orangeburg, SC

731 Citadel Road, Orangeburg
2.5 out of 5.0
3.8 out of 5 (268 reviews)
Found hotel at last minute Pet friendly Staff very friendly Delicious cookies Beautiful landscaping
  Nov 15, 2017

$93

$93
Best Western Plus Santee Inn

Best Western Plus Santee Inn

I 95 Exit 98, Santee
2.5 out of 5.0
4.3 out of 5 (542 reviews)
Great for quick stay on long driveEfficient, clean, and exactly what we expected and needed on a long trip.
  Nov 23, 2017

$109

$109
Hampton Inn Santee I-95

Hampton Inn Santee I-95

9060 Old Number Six Hwy, Santee
2.5 out of 5.0
4.6 out of 5 (429 reviews)
Just over night traveling comfortable and welcoming clean,inviting good breakfast
  Nov 16, 2017

$100

$100
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

221 Britain St, Santee
2.5 out of 5.0
3.9 out of 5 (291 reviews)
Nice place very safe and secure. No problems. I asked questions and got what I needed for my stay.
  Nov 20, 2017

$94

$94
Orangeburg - Days Inn South

Orangeburg - Days Inn South

3402 Five Chop Rd, Orangeburg
2.0 out of 5.0
2.5 out of 5 (131 reviews)
building was niceRoad into the facility is in terrible shape Toilet seat was about to fall off
  Oct 8, 2017

$55

$55
Hampton Inn Manning

Hampton Inn Manning

2822 Paxville Hwy, Manning
2.5 out of 5.0
4.4 out of 5 (224 reviews)
Comfiortabke. Great bedding.Excellent bedding and comfortable beds. Nice hit breakfast.
  Nov 13, 2017

$110

$110
Baymont Inn Manning

Baymont Inn Manning

2284 Raccoon Road, Manning
2.5 out of 5.0
3.6 out of 5 (376 reviews)
Nice hotel Check in was quick. The staff were lovely to deal with. There is a Walmart close by.
  Nov 3, 2017

$71

$71
Quality Inn St George

Quality Inn St George

6014 W Jim Bilton Blvd, St. George
2.5 out of 5.0
3.3 out of 5 (152 reviews)
Along side Interstate 95.Friendly, helpful staff. Breakfast was ready at 6am.
  Nov 10, 2017

$60

$60
Red Roof Inn Santee

Red Roof Inn Santee

9091 Old Hwy 6, Santee
2.0 out of 5.0
2.8 out of 5 (160 reviews)
Last mi uteAlthough lobby needs help the room was a nice siz and clean, beds comfortable and staff helpful. Restaurants nearby
  Oct 2, 2017

$52

$52
Map

When you've got to get away to a new or favorite destination without breaking the bank, Santee awaits with top motels and a change of scenery. Find a new favorite bookstore or hiking trail nearby and watch the world around you, or stay on your feet visiting the top attractions that draw of visitors. You're about to find out why locals and travelers alike love this place.

The Perfect Place at the Ideal Price

Thanks to several convenient locations and comfortable amenities, you'll find motel that meets your vacation needs. Be one of the first travelers to leave a review and share your experience. So, savor the comfort of a well-kept room and attentive hospitality. When you book with Expedia, you can stay all over the world, and the journey starts in Santee.

Reserve a Two-Star Hotel Today!

Plan your trip to Santee now with Expedia's easy online travel booking and start relaxing before you even leave the house. If you need a break from the crowds, you may find that this region offers just the reprieve you've been looking for. Take advantage of the motel availability and easy-going atmosphere.

Recently booked 2 Star Hotels in Santee

Hampton Inn Santee I-95
2.5 out of 5.0
Last booking: 5 hours ago
Comfort Inn & Suites Santee
2.5 out of 5.0
Last booking: 23 hours ago
Red Roof Inn Santee
2.0 out of 5.0
Last booking: 24 hours ago
Howard Johnson Inn Santee
2.0 out of 5.0
Last booking: 33 hours ago
Super 8 Santee
2.0 out of 5.0
Last booking: 34 hours ago
Best Western Plus Santee Inn
2.5 out of 5.0
Last booking: 38 hours ago