Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Buffalo 4 Star Hotels

See all 135 Hotels in Buffalo
Hotel at the Lafayette A Trademark Collection Hotel

Hotel at the Lafayette A Trademark Collection Hotel

391 Washington St, Buffalo
4.0 out of 5.0
4.4 out of 5 (529 reviews)
Historic hotel with updated roomsWe enjoyed our stay at the Lafayette. The Art Deco lobby was like stepping back in time. I’m glad they have kept the look and not modernized it to a generic form. The room was updated and that was appreciated. Nicely done with leather seating and a modern kitchen. We were in a one bedroom suite, ...
  Feb 19, 2018

$111

$111
Wyndham Garden Buffalo Williamsville

Wyndham Garden Buffalo Williamsville

5195 Main Street, Williamsville
4.0 out of 5.0
4.7 out of 5 (770 reviews)
Hotel is very nice and clean. Stuffs are nice and helpful as well.
  Feb 19, 2018

$111

$111
Embassy Suites Buffalo

Embassy Suites Buffalo

200 Delaware Avenue, Buffalo
4.0 out of 5.0
4.5 out of 5 (1,497 reviews)
Great location!!!!Friendly Staff!!!! Rooms were very clean and well decorated. Breakfast was amazing!
  Feb 19, 2018

$118

$118
The Delavan Hotel & Spa

The Delavan Hotel & Spa

6461 Transit Road, Cheektowaga
4.5 out of 5.0
4.6 out of 5 (330 reviews)
Beautiful and clean roomsWonderful experience. Loved the hotel staff and cleanliness.
  Feb 20, 2018

$114

$114
Hotel Henry Urban Resort

Hotel Henry Urban Resort

444 Forest Avenue, Buffalo
4.0 out of 5.0
4.4 out of 5 (81 reviews)
Wonderful staff, hotel and grounds. Amazing food and social atmosphere. Bar served up delicious quality cocktails.
  Feb 19, 2018

$131

$131
The Westin Buffalo

The Westin Buffalo

250 Delaware Ave, Buffalo
4.0 out of 5.0
4.6 out of 5 (56 reviews)
fantastic great rooms, clean hotel, fitness room was top notch, cool restaurant the only knock would be for Jake's Café to be open on the weekends- location was great!! incredibly decorated
  Nov 15, 2017

$152

$152
The Mansion On Delaware Ave

The Mansion On Delaware Ave

414 Delaware Ave, Buffalo
4.5 out of 5.0
4.6 out of 5 (211 reviews)
Great memories! When our daughter said she didn't want any gifts for Christmas, but wanted to make memories, we were lucky to learn about Mansion on Delaware Ave(MODA). While the facility is wonderful and has set a new bar for comfort, excellent food and service... the staff made our stay most memorable! Helpful, ...
  Jan 5, 2018

$191

$191
Reikart House, Buffalo, a Tribute Portfolio Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel

5000 Main Street, Amherst
4.5 out of 5.0
4.8 out of 5 (75 reviews)
Excellent experience. The amenities are great, rooms are designed well with high quality finshies, beds are very comfortable.
  Feb 18, 2018

$139

$139
Buffalo Marriott Niagara

Buffalo Marriott Niagara

1340 Millersport Hwy, Amherst
4.0 out of 5.0
4.0 out of 5 (779 reviews)
Nice Hotel lots of space, great facilities.Wonderful friendly staff, great service from Beth at Breakfast. the Manager Paul, good on him for jumping in when his staff was down with the flu. The sports vibe of the hotel was great. With the exception of the issues with our room heater it was a wonderful stay. Keep up the good service. ...
  Feb 4, 2018

$107

$107
Roycroft Inn

Roycroft Inn

40 S Grove St., East Aurora
4.0 out of 5.0
4.6 out of 5 (169 reviews)
Very nice hotel Very large room, clean, staff very helpful, cozy, great for if you and a significant other are just trying to chill in a little town. Great food and live music at the restaurant - 10 out of 10
  Feb 18, 2018

$145

$145
Map

The get-go of any trip gets started with picking a spot. Buffalo is a popular local with travelers because of all its local amenities. However, "location, location, location" applies to more than just your destination. When you want to make your upcoming holiday unforgettable, it's all about where you wake up each morning.

Hotels as Scenic as the City

Buffalo saw its fair share of visitors last year. Our review section features tips and tricks on which accommodation will meet your desires for a wonderful holiday. The resorts found here aim to make your vacation as enjoyable as your nights spent checking out Buffalo. These hotels work hard to make the facilities and grounds hospitable during your visit. You won't have to venture far for a tasty breakfast, to keep up with your exercise schedule, or a refreshing swim. Buffalo has dozens of terrific accommodations that make for the perfect getaway.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like ultra-comfortable bedding, in-room tea or coffee, and specially designed bathroom products. So, sit back and relax. Moreover, if you find yourself in need of something else, you can trust the staff will try their best to ensure you stay happy during your stay there. These properties are so nice that you'll regret the day you have to leave.

Book a 4-Star Hotel in Buffalo Today!

A trip to Buffalo should be a getaway from your daily worries. Book a 4-star hotel in The City of Good Neighbors soon, because everybody else is as well.

Recently booked 4 Star Hotels in Buffalo

Clarence Inn
2.5 out of 5.0
Last booking: 41 minutes ago
Motel 6 Buffalo Airport
2.5 out of 5.0
Last booking: 1 hour ago
Red Roof Inn Buffalo - Hamburg
2.5 out of 5.0
Last booking: 3 hours ago
Baymont Inn & Suites Buffalo
2.5 out of 5.0
Last booking: 4 hours ago
Red Roof Inn Buffalo - Niagara Airport
2.5 out of 5.0
Last booking: 4 hours ago
Super 8 Hamburg
2.5 out of 5.0
Last booking: 4 hours ago
Salvatores Grand Hotel
3.5 out of 5.0
Last booking: 4 hours ago
Holiday Inn Buffalo - International Airport
3.5 out of 5.0
Last booking: 4 hours ago
Motel 6 Buffalo - Amherst
2.5 out of 5.0
Last booking: 4 hours ago