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Featured Central West End 4 Star Hotels

See all 266 Hotels in Central West End
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis
4.0 out of 5.0
4.3 out of 5 (4,993 reviews)
Staff was very accomidationg. We were upgraded to a room with a view, fee of charge. Arch right across the street and were within walking distance of Lacledes Landing.
  Dec 11, 2017

$79

$79
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive, Maryland Heights
4.0 out of 5.0
3.8 out of 5 (1,840 reviews)
We had an enjoyable night. Food at Final Cut was amazing. Enjoyed the gambling tables and the pillow top beds were very comfortable
  Dec 9, 2017

$87

$87
The Hotel Majestic St. Louis

The Hotel Majestic St. Louis

1019 Pine St, St. Louis
4.0 out of 5.0
3.8 out of 5 (1,114 reviews)
Clean, but a little long in the toothBed was super comfy, good sheets and pillows, breakfast just ok, staff friendly, temperature/HVAC was quiet and great for sleeping with (air blew into room, not over the bed), room was very clean! Carpet, furniture, tub all worn and in need of renovation.
  Dec 10, 2017

$98

$98
HoteLumiere at the Arch

HoteLumiere at the Arch

999 N. 2nd St., St. Louis
4.0 out of 5.0
3.2 out of 5 (394 reviews)
Nice hotel Celebrating my birthday. Came into a party in the lobby with a live band it was great!
  Dec 10, 2017

$79

$79
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street, St. Louis
4.5 out of 5.0
4.3 out of 5 (1,790 reviews)
Kids loved it My kids loved the grand hall and the polar express was priceless for the kids.
  Dec 12, 2017

$106

$106
City Place St. Louis - Downtown Hotel

City Place St. Louis - Downtown Hotel

200 North 4th Street, St. Louis
4.0 out of 5.0
3.3 out of 5 (3,685 reviews)
Fabulous downtown locationGreat hotel overall. I would definitely stay here again. We stayed in the 2 room suite and it is very spacious and comfortable. Only one thing was sub-standard - not enough outlets and some of them didn't work. Basically comes with older structures, but nothing that can't be worked around, just bring ...
  Dec 1, 2017

$79

$79
Marriott St. Louis Grand

Marriott St. Louis Grand

800 Washington Ave, St. Louis
4.0 out of 5.0
4.2 out of 5 (256 reviews)
Beautiful hotel in the heart of St. Louis.We were in town for a the Hot Chocolate race and the Marriott was one of the host hotels. It was fairly close to our course. It was pretty easy to find and the parking garage was only a block away from the main entrance. The lobby and rooms were beautiful, especially with the lit Christmas trees. ...
  Dec 11, 2017

$115

$115
River City Casino & Hotel

River City Casino & Hotel

777 River City Casino Blvd, St. Louis
4.5 out of 5.0
4.6 out of 5 (821 reviews)
GetawayJust wanted to get away by myself I felt very safe security is very good you need a room key to even use elavator to your room. Would highly recommend this hotel to evertone
  Dec 6, 2017

$110

$110
The Cheshire

The Cheshire

6300 Clayton Rd, Richmond Heights
4.0 out of 5.0
4.2 out of 5 (1,367 reviews)
UK Museum and charmIt was so lovely for my kids and I to stay at the Cheshire. We were immersed into the charm and history of the experience. My kids were interested in the Queen of England and wanted to read the books provided by the hotel. I adored the old world paintings on the walls and the cozy feel of the lobby. ...
  Dec 5, 2017

$143

$143
Moonrise Hotel

Moonrise Hotel

6177 Delmar Blvd, St. Louis
4.5 out of 5.0
4.7 out of 5 (1,668 reviews)
Cool place friendly staff clean room easy parking. wife loved it. Fun area.
  Dec 11, 2017

$127

$127
Map

The preparation of any well-deserved holiday starts with selecting a great location. Central West End has become a popular destination with guests because of everything it offers. Location is everything, but that doesn't mean just the town you are flying into. When you want a holiday that is fantastic from start to finish, you need the right place to stay.

Lodgings as Picturesque as the City

Central West End saw its fair share of visitors last year. Expedia's review section includes comments on which hotel will meet your needs for an astounding holiday. The resorts found here aim to make your stay as delightful as your evenings out in Central West End. You won't have to venture far for an invigorating dip, delectable dinner, or to keep up with your exercise routine during your visit, thanks to everything these hotels offer. They work hard to make the facilities and grounds welcoming from the second you step onto the property and with every step across their floors.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like ultra-comfortable bedding, in-room tea or coffee, and specially designed bathroom products. So, lay back and relax. Moreover, if you find yourself in need of something else, you can trust the staff will try their hardest to ensure you stay satisfied during your time. These accommodations are so nice that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Central West End Today!

A holiday to Central West End should be one that you'll recollect for years to come, and reserving a 4-star hotel can help create memories that are nothing but incredible. Your trip should be geared toward getting the very most out of your destination. And getting the most means giving yourself the very best. Expedia offers 4-star properties that allow you to do just that. Book through Expedia today!

Recently booked 4 Star Hotels in Central West End

The Parkway Hotel
3.5 out of 5.0
Last booking: 35 minutes ago
The Chase Park Plaza Royal Sonesta St. Louis
5.0 out of 5.0
Last booking: 17 hours ago
Holiday Inn Express St Louis - Central West End
3.5 out of 5.0
Last booking: 20 hours ago