An aerial view of a coastal town with clear blue waters, a marina, and a long pier extending into the sea.

Find 4 Star Hotels in Duck Key, FL from $221

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Check availability on Duck Key 4 Star Hotels

Tonight
Oct 9 - Oct 10
Tomorrow
Oct 10 - Oct 11
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Duck Key 4-star hotels

A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A spacious lobby with high ceilings, large windows, and a central coffee table surrounded by sofas and chairs.
An aerial view of a coastal resort with multiple white buildings, a clear turquoise sea, and lush greenery.
A pathway leading to a pool area with palm trees and a sunset view.

1. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Katherine
$272 nightly
$304 total
Oct 18 - Oct 19
Total with taxes and fees
Hawks Cay Resort
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A beach with palm trees, a dock, and lounge chairs.
A hotel room with a bed, a sofa, a coffee table, a desk with a lamp, and a view of the ocean.
An aerial view of a resort with a swimming pool, palm trees, and a dock.

2. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
Danielle
$206 nightly
$232 total
Oct 21 - Oct 22
Total with taxes and fees
Amara Cay Resort
A swimming pool surrounded by palm trees and lounge chairs.
A beach scene with a wooden deck, palm trees, and a gazebo-like structure.
A spacious living room with a wooden coffee table, a striped sofa, and a television on a wooden cabinet.
A wooden deck with blue chairs overlooking a beach with palm trees and the ocean.

3. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United Kingdom
Stuart
$247 nightly
$278 total
Oct 20 - Oct 21
Total with taxes and fees
Tranquility Bay Beachfront Hotel and Resort
A marina with boats docked, a lighthouse, and a resort with outdoor seating.
A room with two sofas, a round coffee table, and a small side table with a vase.
A bar area with a long counter, multiple bar stools, and a view of the marina with boats and palm trees.
A spacious lobby with a central round table, surrounded by wicker chairs, large potted plants, and decorative lanterns.

4. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
United States
Rick
$197 nightly
$221 total
Oct 18 - Oct 19
Total with taxes and fees
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A row of colorful beach huts with palm trees in the background.
A beach resort with palm trees, a thatched hut, and a purple building with a window.
A beach with colorful buildings, kayaks, and lounge chairs.

5. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
$252 nightly
$283 total
Nov 8 - Nov 9
Total with taxes and fees
La Siesta Resort & Villas
A wooden deck with a pool and chairs overlooking a beach with palm trees.
A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.
A bar area with stools, a counter, and hanging lanterns.
A pool area with palm trees and a view of the ocean.

6. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
$226 nightly
$254 total
Oct 12 - Oct 13
Total with taxes and fees
Grassy Flats Resort & Beach Club
A resort pool with palm trees and lounge chairs, surrounded by a beachfront.
A modern living room with a sofa, chairs, a dining table, a TV, and a view of the ocean.
A resort with a large pool surrounded by lounge chairs, a beach area, and a building with multiple floors.
A modern kitchen with white cabinetry, a stainless steel oven, and a large island with a bowl of fruit.

7. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Gabriela
$604 nightly
$680 total
Oct 30 - Oct 31
Total with taxes and fees
Villas At Hawks Cay Resort
A large hotel with a pool, multiple balconies, and palm trees.
A large, two-story hotel with a swimming pool in front.
A beach with clear water and gentle waves.
A beachside wedding setup with wicker chairs and a white canopy, palm trees, and a sunset view.

8. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina
A covered outdoor area with a wooden deck, white railings, and a view of the ocean.
A resort with multiple buildings, a large central pool, and a view of the ocean.
An aerial view of a coastal resort with multiple buildings, a marina, and clear blue waters.
A poolside area with lounge chairs and palm trees.

9. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
A living room with a sofa, a glass coffee table, a television on a cabinet, and a sliding glass door leading to an outdoor area.
A living room with a sofa, armchair, and coffee table, a dining area with a table and chairs, and a kitchen in the background.
A sandy area with a water body, surrounded by greenery and a building with a flat roof.
A modern kitchen with white cabinets, stainless steel appliances, and a granite countertop.

10. Oceanfront Duck Key Villa: 2 Marinas Steps Away!

Oceanfront Duck Key Villa: 2 Marinas Steps Away!
Marathon
Oceanfront Duck Key Villa: 2 Marinas Steps Away!
Interior
A modern kitchen with a central island, bar stools, and a ceiling fan.
A modern kitchen with white cabinetry, a built-in oven, and a large island with stools.
A beach with clear turquoise water, a wooden pier, and a rocky shoreline.

11. Florida Keys Getaway w/ Stunning Ocean Views

Florida Keys Getaway w/ Stunning Ocean Views
Long Key
Florida Keys Getaway w/ Stunning Ocean Views
Beach/ocean view
In-room dining
Property grounds
Property grounds

12. One-bedroom Apartment

One-bedroom Apartment
Marathon
One-bedroom Apartment
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Duck Key.
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
$296 nightly
$334 total
Oct 20 - Oct 21
Total with taxes and fees
Isla Bella Beach Resort & Spa
Sea Glass Cove

Sea Glass Cove

59720 Overseas Hwy Marathon FL
Get ratesSea Glass Cove
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Duck Key

Kayak through mangrove tunnels and spot colorful fish in the crystal-clear waters surrounding this tiny island paradise. Unwind at Hawks Cay Resort's saltwater lagoon or take a short trip to Marathon for the Turtle Hospital's educational tours.

See all hotels in Duck Key
A coastal city with a long bridge connecting to an island, surrounded by clear blue waters and numerous boats.

Top Duck Key Hotel Reviews

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

10/10 Excellent
"Good"
Pablo Miguel 1-night trip
Posted 16 hours ago
Tranquility Bay Beachfront Hotel and Resort
Hawks Cay Resort

Hawks Cay Resort

10/10 Excellent
"Great hotel. Definitely coming back!"
Kasil 2-night trip
Posted 16 hours ago
Hawks Cay Resort
Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"Very clean resort. The pool was fabulous. The tiki bar was great. Stall friendly and helpful. Truly enjoyed my stay!"
Maureen 2-night trip
Posted 3 days ago
Amara Cay Resort

Find out more about Duck Key

The get-go of any vacation starts with choosing a spot. Duck Key has become a popular choice with guests because of everything it offers. However, "location, location, location" applies to more than just what city where your plane lands. When you want a journey that is enjoyable from start to finish, you need the perfect place to stay.

Hotels as Beautiful as the City

Duck Key saw its fair share of visitors in the last year. Expedia's review section boast comments which may help you choose the room that is the perfect fit for your trip. When you book a 4-star hotel room you can relax knowing that these properties are designed to meet your needs. You won't have to go far for a nice lunch, an energizing spa treatment, or to sustain your workout schedule during your visit, thanks to everything these hotels provide. They strive to make the grounds and facilities welcoming from the moment you step out of your car and with every step throughout the hotel.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like premium bedding, designer bathroom products, and in-room coffee or tea. So, sit back and relax. Moreover, if you find yourself in need of anything more, you can be confident the staff will do their best to ensure you stay happy during your stay there. These properties are so lovely that you'll regret the day you have to fly back home.

Reserve a 4-Star Hotel in Duck Key Today!

Your trip to Duck Key should be a complete break from your daily routine. Check out Expedia's large assortment of 4-star hotels in Duck Key that will bring your vacation to greater heights.

Frequently asked questions

What are the best 4-star hotels in Duck Key?
Kick back in upmarket comfort at Hawks Cay Resort. According to reviews by Expedia guests, this is one of Duck Key's favorite 4-star hotels.
How much does it cost to stay in a 4-star hotel in Duck Key?
With Expedia's filter tool, locking in an awesome deal on a 4-star hotel in Duck Key just got easier. Start by keying in your chosen travel dates and length of your trip. Then sort the results by price and choose a property that best suits your style and budget.
  • Search for the lowest price from $334
What's the difference between 5-star and 4-star hotels in Duck Key?
Offering an inviting traveler experience and upscale décor, 4-star hotels are a fantastic option for your Duck Key vacation. These kinds of accommodations generally come with lots of handy amenities that make it simple to unpack and recharge — think complimentary bathrobes, pools and restaurants. Or get a taste of the high life at a 5-star hotel designed to spoil you with luxury perks and amenities. Full-service health clubs, premium toiletries and world-class dining are typically featured at these deluxe properties.

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