Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Eastern Rome 4 Star Hotels

See all 5,514 Hotels in Eastern Rome
Starhotels Michelangelo

Starhotels Michelangelo

Via Della Stazione Di San Pietro 14, Rome
    4.0 out of 5.0
     
     
    4.4 out of 5 (3,212 reviews)
    Very Nice Hotel. Enjoyed our stay there very much. The hotel is a short walking distance from the Vatican. Located in a relatively quiet area. with cafes and stores nearby. Room was clean and neat, closet was small but adequate for our stay. The dining area and breakfast brunch was excellent, with ...
    May 22, 2018

    Starhotels Michelangelo$122

    Starhotels Michelangelo$122
    UNA Hotel Roma

    UNA Hotel Roma

    Via Giovanni Amendola, 57, Rome
      4.0 out of 5.0
       
       
      4.4 out of 5 (2,077 reviews)

      UNA Hotel Roma$172

      UNA Hotel Roma$172
      Napoleon Hotel

      Napoleon Hotel

      Piazza Vittorio Emanuele II 105, Rome
        4.0 out of 5.0
         
         
        4.4 out of 5 (1,970 reviews)
        Really nice hotel, great staff and nice rooms, to top that the food is pretty good too and very reasonable. Nicely positioned as you step out of the metro you almost walk into the Hotel, making it easy so easy to travel round Rome, the hotel management sent us a complimentary bottle of bubbly on ...
        May 21, 2018

        Napoleon Hotel$167

        Napoleon Hotel$167
        Welcome Piram Hotel

        Welcome Piram Hotel

        Via Giovanni Amendola 7, Rome
          4.0 out of 5.0
           
           
          3.8 out of 5 (1,970 reviews)
          We loved the location of this hotel. We were in Rome to go on a 10 day Italy and Greek Isles cruise. Being so close to the Termini station made it very easy to get to the port for our cruise. The room was very nice. The staff was very friendly, too.
          May 9, 2018
          Starhotels Metropole

          Starhotels Metropole

          Via Principe Amedeo 3, Rome
            4.0 out of 5.0
             
             
            4.3 out of 5 (2,088 reviews)

            Starhotels Metropole$154

            Starhotels Metropole$154
            Hotel Quirinale

            Hotel Quirinale

            Via Nazionale 7, Rome
              4.0 out of 5.0
               
               
              4.1 out of 5 (2,576 reviews)
              Nice & clean, close to city for tourist spots Facilities& appointments including Courtyard Bar greatetc
              May 21, 2018

              Hotel Quirinale$164

              Hotel Quirinale$164
              The Tribune Hotel

              The Tribune Hotel

              Via Campania, 45, Rome
                4.0 out of 5.0
                 
                 
                4.7 out of 5 (452 reviews)
                Trendy hotel in nice area Me and my partner enjoyed our stay at the tribune hotel, it offers stylish rooms and breakfast/dining areas and extremely friendly and helpful staff. It is situated in a good area close to the spanish steps etc. Overall would recommend and stay again.
                May 19, 2018

                The Tribune Hotel$217

                The Tribune Hotel$217
                Hotel Delle Nazioni

                Hotel Delle Nazioni

                Via Poli 7, Rome
                  4.0 out of 5.0
                   
                   
                  4.2 out of 5 (1,784 reviews)
                  Location great mattresses and pillows horrible.
                  May 20, 2018

                  Hotel Delle Nazioni$146

                  Hotel Delle Nazioni$146
                  Hotel Cosmopolita

                  Hotel Cosmopolita

                  Via Santa Eufemia, 5, Rome
                    4.0 out of 5.0
                     
                     
                    4.0 out of 5 (2,040 reviews)
                    A good hotel in a great location for attractions. on a busy road if your in certain rooms so just be aware we didn’t find it a problem but some will. Kettle in the room. Good sized room for a base for a few days. Good sized shower. Overall a good hotel.
                    May 21, 2018

                    Hotel Cosmopolita$116

                    Hotel Cosmopolita$116
                    Hotel Artemide

                    Hotel Artemide

                    Via Nazionale 22, Rome
                      4.0 out of 5.0
                       
                       
                      4.8 out of 5 (2,097 reviews)
                      Very nice hotel not far from many of the famous landmarks. We were able to walk to many of these - Trevi Fountain. Spanish Steps. Colosseum included. Shops and pizzerias on your doorstep and a very pleasant bar and restaurant on the top floor\rooftop. Breakfast to suit most tastes I would have thought ...
                      May 21, 2018

                      Hotel Artemide$199

                      Hotel Artemide$199
                      Map

                      The beginning of any well-deserved trip kicks off with picking a location. Eastern Rome has become a popular destination with tourists because of all its local amenities. Location is everything, but that applies to more than the city you are flying into. When you want a vacation that is amazing from start to finish, you need the right hotel.

                      Lodgings as Gorgeous as Eastern Rome

                      Eastern Rome saw its fair share of visitors this past year. Expedia's review section boast reviews on which property will satisfy your wishes for an unbelievable trip. The resorts found here strive to make your stay as gratifying as your days and evenings exploring Eastern Rome. You'll never have to venture far for a gourmet dinner, to sustain your workout schedule, or an energizing dip during your vacation, thanks to everything these hotels provide. They strive to make the grounds and facilities pleasing from the moment you step out of your car and with every step throughout the hotel.

                      Rooms have been designed to keep you as comfortable as possible, with amenities like ultra-comfortable bedding, specially designed bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something more, you can trust the staff will work their hardest to ensure you continue to be happy during your stay there. These hotels are so nice that you'll regret the day you have to go back home.

                      Reserve a 4-Star Hotel in Eastern Rome Today!

                      A getaway to Eastern Rome should be one where you won't have to worry about the little things. Browse Expedia's great number of 4-star hotels in Eastern Rome that will bring your trip to greater heights.