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Featured Florida Keys 4 Star Hotels

See all 856 Hotels in Florida Keys
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
    4.0 out of 5.0
     
     
    4.5 out of 5 (3,401 reviews)
    A Key West GemWe stayed in the Dewey house and had a lovely private room. An excellent breakfast and snack ( think lunch) was included. The adults only pool was a quiet and welcome respite from the usual high intensity from the usual pool scene.
    May 19, 2018

    Southernmost Beach Resort$221

    Southernmost Beach Resort$221
    Oceans Edge Key West Resort, Hotel & Marina

    Oceans Edge Key West Resort, Hotel & Marina

    5950 Peninsular Avenue, Key West
      4.0 out of 5.0
       
       
      4.5 out of 5 (536 reviews)
      Overall good but...Bad views, next to the swamp The keys dis nit work and had to run down to office Coffee machine did not work
      May 19, 2018

      Oceans Edge Key West Resort, Hotel & Marina$118

      Oceans Edge Key West Resort, Hotel & Marina$118
      The Perry Hotel Key West

      The Perry Hotel Key West

      7001 Shrimp Road, Key West
        4.0 out of 5.0
         
         
        4.6 out of 5 (184 reviews)
        Great Hotel The Perry was a great choice for our vacation. Nice rooms, very friendly and helpful staff, great food and drinks, very nice pool...what more do you want? If we ever go back to Key West we will be staying there again.
        Apr 28, 2018

        The Perry Hotel Key West$169

        The Perry Hotel Key West$169
        Margaritaville Key West Resort & Marina

        Margaritaville Key West Resort & Marina

        245 Front Street, Key West
          4.0 out of 5.0
           
           
          4.3 out of 5 (287 reviews)
          Good locationClose to Duval street action, and can lounge at pool to recouperate , good food poolside look
          May 7, 2018

          Margaritaville Key West Resort & Marina$251

          Margaritaville Key West Resort & Marina$251
          24 North Hotel Key West

          24 North Hotel Key West

          3820 North Roosevelt Boulevard, Key West
            4.0 out of 5.0
             
             
            4.1 out of 5 (1,212 reviews)
            Great LocationNice to stay right at the hotel and relax all day after a long night out on Duval Street. Visit the blinded pig food truck right on sight anytime of the night and wake up and go Enjoy a Bloody Mary at the pool bar Coconuts and order some brunch pool side. Such a great place to stay has it all right ...
            May 5, 2018

            24 North Hotel Key West$127

            24 North Hotel Key West$127
            The Gates Hotel Key West

            The Gates Hotel Key West

            3824 N Roosevelt Blvd, Key West
              4.0 out of 5.0
               
               
              4.3 out of 5 (1,225 reviews)
              Great place in Key WestDefinitely would recommend this hotel for a gateway in Key West. The free shuttle to downtown is very convenient, it avoids you to look for a place to park, which is tough when you get close to Mallory Square. If you want to still go with your car, be careful don;t get trapped in $20 parking lot, ...
              May 11, 2018

              The Gates Hotel Key West$144

              The Gates Hotel Key West$144
              Pier House Resort & Spa

              Pier House Resort & Spa

              1 Duval St, Key West
                4.0 out of 5.0
                 
                 
                4.4 out of 5 (1,533 reviews)
                Great place to stay ! No need to say anymore !Brought my wife down for her 50th Birthday we had a great time! The staff ! Always nice and friendly been there 3 times ! , rooms are nice ,hated to leave Highly recommend
                May 11, 2018

                Pier House Resort & Spa$300

                Pier House Resort & Spa$300
                Casa Marina, A Waldorf Astoria Resort

                Casa Marina, A Waldorf Astoria Resort

                1500 Reynolds Street, Key West
                  4.0 out of 5.0
                   
                   
                  4.2 out of 5 (2,190 reviews)
                  Classic luxury - modern amenitiesMr. Flagler knew what he was doing when he built the place. We had a king suite beach walkout and stepped right on to the sand. Room was laid out great, friendly staff, nice pool, easy to use water equipment and bikes etc. This is a higher end resort so you will pay for what you use - for example, ...
                  May 7, 2018

                  Casa Marina, A Waldorf Astoria Resort$305

                  Casa Marina, A Waldorf Astoria Resort$305
                  The Marker Waterfront Resort Key West

                  The Marker Waterfront Resort Key West

                  200 William Street, Key West
                    4.0 out of 5.0
                     
                     
                    4.6 out of 5 (966 reviews)
                    Clean and close to everythingThe Marker is perfectly situated near everything. The hotel is clean and updated. The hotel is walkable to bars and restaurants, as well as, Key West tourist attractions. The pools are smaller than your larger hotels, but with three of them and not many guests, there is no problem getting a seat. ...
                    May 9, 2018

                    The Marker Waterfront Resort Key West$195

                    The Marker Waterfront Resort Key West$195
                    Tranquility Bay Beachfront Hotel and Resort

                    Tranquility Bay Beachfront Hotel and Resort

                    2600 Overseas Hwy, Marathon
                      4.0 out of 5.0
                       
                       
                      4.5 out of 5 (1,110 reviews)
                      Beautiful view from any angleSpacious and very clean No contact at all from management staff which was disappointing after 8 days stay Dining was overpriced Facilities were beautiful and lots to see and do in Marathon
                      May 3, 2018

                      Tranquility Bay Beachfront Hotel and Resort$149

                      Tranquility Bay Beachfront Hotel and Resort$149
                      Map

                      You'll see that you are in fine company with a visit to Florida Keys. Vacationers similar to you have made it one of our top most visited locals the past two years. However, "location, location, location" applies to more than just your vacation destination. When you want to make your next vacation extra special, it's all about where you start each new day.

                      Properties as Gorgeous as Florida Keys

                      Florida Keys saw thousands of tourists in 2016, and Expedia's comment section boast comments that highlight how fabulous these properties are. When you book a 4-star hotel you can breathe easy knowing that these properties aim to exceed your needs. You'll never have to search for to sustain your exercise routine, an energizing swim, or nice dinner during your stay, thanks to all that these hotels provide. They aim to make their facilities and grounds pleasing from the instant you step onto the property and with every step across their floors. Florida Keys has dozens of wonderful lodgings that make for the ideal holiday.

                      Rooms have been fashioned to keep you as comfortable as possible, with amenities like premium bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something else, you can trust the staff will do their best to ensure you continue to be pleased during your stay there. These accommodations are so lovely that you'll regret the day you have to return home.

                      Book a 4-Star Hotel in Florida Keys Today!

                      A trip to Florida Keys should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are fabulous. Book a 4-star hotel in Florida Keys soon, because several other people are too.

                      Recently booked 4 Star Hotels in Florida Keys

                      Chesapeake Beach Resort
                      2.5 out of 5.0
                      Last booking: 3 minutes ago
                      Holiday Inn Express Hotel & Suites Marathon
                      2.5 out of 5.0
                      Last booking: 8 minutes ago
                      Heron House Court - Adult Only
                      3.0 out of 5.0
                      Last booking: 8 minutes ago
                      La Siesta Resort & Marina
                      3.0 out of 5.0
                      Last booking: 14 minutes ago
                      The Cabana Inn Key West-Adults Only
                      3.0 out of 5.0
                      Last booking: 25 minutes ago
                      Hyatt Centric Key West Resort and Spa
                      4.0 out of 5.0
                      Last booking: 45 minutes ago
                      Orchid Key Inn
                      3.5 out of 5.0
                      Last booking: 52 minutes ago
                      The Gates Hotel Key West
                      4.0 out of 5.0
                      Last booking: 54 minutes ago
                      Mangrove Marina and Resort Aqualodge Houseboats
                      3.0 out of 5.0
                      Last booking: 1 hour ago