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Featured Florida Keys 4 Star Hotels

See all 848 Properties in Florida Keys
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (3,462 reviews)
Good location but underwhelmedFor the price I expected a bit more / nicer accommodations. Could not figure out the A/C situation for the life of me (I couldn't seem to adjust the temperature. although it was on). I picked this hotel because it seemed to be the only hotel with a real beach, which is kind of true. Hotel was just ...
Jun 18, 2018
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (567 reviews)
Beautiful HotelThe hotel facade and hampton's style decorating is perfection, the grounds and facilities excellent. The location of the building that we stayed in was poor and far away from everything, try and avoid Building 4 if you can, access to everything from here is not thought through. The hotel reception ...
Jun 13, 2018
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (310 reviews)
Highly recommendWe only stayed for a short time. Hotel was nice and clean. Staff was great, lots of amenities and right in the middle of everything.
Jun 16, 2018
The Perry Hotel Key West

The Perry Hotel Key West

7001 Shrimp Road, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.6 out of 5 (217 reviews)
Better than expectedOff the beaten path but a welcome change of pace with a great atmosphere. Industrial modern feel with great views of the marina. Very comfortable room. Staff friendly and accommodating. Restaraunt on site had an excellent Mahi sandwich. Definitely worth at least one meal while here. Would stay here ...
Jun 15, 2018
24 North Hotel Key West

24 North Hotel Key West

3820 North Roosevelt Boulevard, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.1 out of 5 (1,238 reviews)
Fair. O.K.Rust running down the shower towel rack can be easily fixed, but is not. Room not as clean as it should be. 3 great hotel staff members at desk. Young man not helpful. Pool area good and outside bar very nice. 1/2 price drinks appreciated (made real price reasonable). Just charge 1/2 prince to drink ...
Jun 4, 2018
The Gates Hotel Key West

The Gates Hotel Key West

3824 N Roosevelt Blvd, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (1,253 reviews)
Awesome hotel Free shuttle was awesome but still only a 5-10 min drive if we chose to drive into town ourselves. Room was clean, well decorated, and comfortable. It did have a little bit of a musty smell when we initially walked in but most likely from the humidity. Check in and check out was smooth. Pool and ...
Jun 19, 2018

The Gates Hotel Key West$161

The Gates Hotel Key West$161
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.4 out of 5 (1,554 reviews)
Wonderful hotel with a beachGreat hotel with a beautiful beach and great amenities. Would definitely return to this resort and recommend it to friends
Jun 11, 2018
Casa Marina, A Waldorf Astoria Resort

Casa Marina, A Waldorf Astoria Resort

1500 Reynolds Street, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.2 out of 5 (2,199 reviews)
Classic luxury - modern amenitiesMr. Flagler knew what he was doing when he built the place. We had a king suite beach walkout and stepped right on to the sand. Room was laid out great, friendly staff, nice pool, easy to use water equipment and bikes etc. This is a higher end resort so you will pay for what you use - for example, ...
May 7, 2018

Casa Marina, A Waldorf Astoria Resort$269

Casa Marina, A Waldorf Astoria Resort$269
The Marker Waterfront Resort Key West

The Marker Waterfront Resort Key West

200 William Street, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (984 reviews)
Very nice resort right next to oceanThis was a great place! Clean and friendly and in a great location to walk everywhere!
Jun 20, 2018

The Marker Waterfront Resort Key West$169

The Marker Waterfront Resort Key West$169
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (1,130 reviews)
Beautiful view from any angleSpacious and very clean No contact at all from management staff which was disappointing after 8 days stay Dining was overpriced Facilities were beautiful and lots to see and do in Marathon
May 3, 2018

Tranquility Bay Beachfront Hotel and Resort$224

Tranquility Bay Beachfront Hotel and Resort$224
Map

You'll see that you are in fine company with a visit to Florida Keys. Vacationers similar to you have made it one of our top most visited locals the past two years. However, "location, location, location" applies to more than just your vacation destination. When you want to make your next vacation extra special, it's all about where you start each new day.

Properties as Gorgeous as Florida Keys

Florida Keys saw thousands of tourists in 2016, and Expedia's comment section boast comments that highlight how fabulous these properties are. When you book a 4-star hotel you can breathe easy knowing that these properties aim to exceed your needs. You'll never have to search for to sustain your exercise routine, an energizing swim, or nice dinner during your stay, thanks to all that these hotels provide. They aim to make their facilities and grounds pleasing from the instant you step onto the property and with every step across their floors. Florida Keys has dozens of wonderful lodgings that make for the ideal holiday.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like premium bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something else, you can trust the staff will do their best to ensure you continue to be pleased during your stay there. These accommodations are so lovely that you'll regret the day you have to return home.

Book a 4-Star Hotel in Florida Keys Today!

A trip to Florida Keys should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are fabulous. Book a 4-star hotel in Florida Keys soon, because several other people are too.

Recently booked 4 Star Hotels in Florida Keys

Creekside Inn Islamorada
2.5 out of 5.0
Last booking: 3 hours ago
Bay Harbor Lodge
3.0 out of 5.0
Last booking: 3 hours ago
Casa Marina, A Waldorf Astoria Resort
4.0 out of 5.0
Last booking: 4 hours ago
The Southernmost Inn-Adults Only
2.5 out of 5.0
Last booking: 4 hours ago
Pier House Resort & Spa
4.0 out of 5.0
Last booking: 4 hours ago
DoubleTree Resort by Hilton Grand Key - Key West
3.5 out of 5.0
Last booking: 4 hours ago
Fairfield Inn and Suites by Marriott Key West
3.5 out of 5.0
Last booking: 4 hours ago
Heron House Court - Adult Only
3.0 out of 5.0
Last booking: 5 hours ago
Skipjack Resort & Marina
3.0 out of 5.0
Last booking: 5 hours ago