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Check prices on hotels in Florida Keys

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Featured Florida Keys 4 Star Hotels

See all 848 Properties in Florida Keys
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
    4.0 out of 5.0
     
     
    4.5 out of 5 (3,472 reviews)
    Not the last time I hopeThis was our first time staying at the Dewey's house, B&B in general for the first time as well. Excellent room and staff! Will recommend over waldord or any other big resorts! Such an awesome hotel and LT was so great when she greeted us at the door when we first came in. We loved the breakfast ...
    Jun 21, 2018

    Southernmost Beach Resort$229

    Southernmost Beach Resort$229
    Oceans Edge Key West Resort, Hotel & Marina

    Oceans Edge Key West Resort, Hotel & Marina

    5950 Peninsular Avenue, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.5 out of 5 (567 reviews)
    10 Stayed for 5 days and it was beautiful! Pools are clean, food was great, drinks and bartenders were awesome and not far from everything. The shuttle is nice too! Thank you oceans edge!
    Jun 6, 2018

    Oceans Edge Key West Resort, Hotel & Marina$134

    Oceans Edge Key West Resort, Hotel & Marina$134
    Margaritaville Key West Resort & Marina

    Margaritaville Key West Resort & Marina

    245 Front Street, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.3 out of 5 (314 reviews)
    Highly recommendWe only stayed for a short time. Hotel was nice and clean. Staff was great, lots of amenities and right in the middle of everything.
    Jun 16, 2018

    Margaritaville Key West Resort & Marina$250

    Margaritaville Key West Resort & Marina$250
    The Perry Hotel Key West

    The Perry Hotel Key West

    7001 Shrimp Road, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.6 out of 5 (221 reviews)
    Better than expectedOff the beaten path but a welcome change of pace with a great atmosphere. Industrial modern feel with great views of the marina. Very comfortable room. Staff friendly and accommodating. Restaraunt on site had an excellent Mahi sandwich. Definitely worth at least one meal while here. Would stay here ...
    Jun 15, 2018
    24 North Hotel Key West

    24 North Hotel Key West

    3820 North Roosevelt Boulevard, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.1 out of 5 (1,241 reviews)
    Fair. O.K.Rust running down the shower towel rack can be easily fixed, but is not. Room not as clean as it should be. 3 great hotel staff members at desk. Young man not helpful. Pool area good and outside bar very nice. 1/2 price drinks appreciated (made real price reasonable). Just charge 1/2 prince to drink ...
    Jun 4, 2018

    24 North Hotel Key West$152

    24 North Hotel Key West$152
    The Gates Hotel Key West

    The Gates Hotel Key West

    3824 N Roosevelt Blvd, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.3 out of 5 (1,255 reviews)
    Awesome hotel Free shuttle was awesome but still only a 5-10 min drive if we chose to drive into town ourselves. Room was clean, well decorated, and comfortable. It did have a little bit of a musty smell when we initially walked in but most likely from the humidity. Check in and check out was smooth. Pool and ...
    Jun 19, 2018

    The Gates Hotel Key West$161

    The Gates Hotel Key West$161
    Pier House Resort & Spa

    Pier House Resort & Spa

    1 Duval St, Key West
      4.0 out of 5.0
       
       
      4.4 out of 5 (1,554 reviews)
      Wonderful hotel with a beachGreat hotel with a beautiful beach and great amenities. Would definitely return to this resort and recommend it to friends
      Jun 11, 2018

      Pier House Resort & Spa$290

      Pier House Resort & Spa$290
      Casa Marina, A Waldorf Astoria Resort

      Casa Marina, A Waldorf Astoria Resort

      1500 Reynolds Street, Key West
        4.0 out of 5.0
         
         
        4.2 out of 5 (2,196 reviews)
        Classic luxury - modern amenitiesMr. Flagler knew what he was doing when he built the place. We had a king suite beach walkout and stepped right on to the sand. Room was laid out great, friendly staff, nice pool, easy to use water equipment and bikes etc. This is a higher end resort so you will pay for what you use - for example, ...
        May 7, 2018

        Casa Marina, A Waldorf Astoria Resort$268

        Casa Marina, A Waldorf Astoria Resort$268
        The Marker Waterfront Resort Key West

        The Marker Waterfront Resort Key West

        200 William Street, Key West
        • Free Cancellation
        • Reserve now, pay when you stay
        4.0 out of 5.0
         
         
        4.5 out of 5 (989 reviews)
        Very nice resort right next to oceanThis was a great place! Clean and friendly and in a great location to walk everywhere!
        Jun 20, 2018

        The Marker Waterfront Resort Key West$169

        The Marker Waterfront Resort Key West$169
        Tranquility Bay Beachfront Hotel and Resort

        Tranquility Bay Beachfront Hotel and Resort

        2600 Overseas Hwy, Marathon
        • Free Cancellation
        • Reserve now, pay when you stay
        4.0 out of 5.0
         
         
        4.5 out of 5 (1,135 reviews)
        Beautiful view from any angleSpacious and very clean No contact at all from management staff which was disappointing after 8 days stay Dining was overpriced Facilities were beautiful and lots to see and do in Marathon
        May 3, 2018
        Map

        You'll see that you are in fine company with a visit to Florida Keys. Vacationers similar to you have made it one of our top most visited locals the past two years. However, "location, location, location" applies to more than just your vacation destination. When you want to make your next vacation extra special, it's all about where you start each new day.

        Properties as Gorgeous as Florida Keys

        Florida Keys saw thousands of tourists in 2016, and Expedia's comment section boast comments that highlight how fabulous these properties are. When you book a 4-star hotel you can breathe easy knowing that these properties aim to exceed your needs. You'll never have to search for to sustain your exercise routine, an energizing swim, or nice dinner during your stay, thanks to all that these hotels provide. They aim to make their facilities and grounds pleasing from the instant you step onto the property and with every step across their floors. Florida Keys has dozens of wonderful lodgings that make for the ideal holiday.

        Rooms have been fashioned to keep you as comfortable as possible, with amenities like premium bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something else, you can trust the staff will do their best to ensure you continue to be pleased during your stay there. These accommodations are so lovely that you'll regret the day you have to return home.

        Book a 4-Star Hotel in Florida Keys Today!

        A trip to Florida Keys should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are fabulous. Book a 4-star hotel in Florida Keys soon, because several other people are too.

        Recently booked 4 Star Hotels in Florida Keys

        Skipjack Resort & Marina
        3.0 out of 5.0
        Last booking: 43 hours ago
        Casa Marina, A Waldorf Astoria Resort
        4.0 out of 5.0
        Last booking: 44 hours ago
        Fairfield Inn and Suites by Marriott Key West
        3.5 out of 5.0
        Last booking: 44 hours ago
        Tranquility Bay Beachfront Hotel and Resort
        4.0 out of 5.0
        Last booking: 44 hours ago
        Amara Cay Resort
        3.5 out of 5.0
        Last booking: 44 hours ago
        Looe Key Reef Resort
        2.5 out of 5.0
        Last booking: 44 hours ago
        Santa Maria Suites
        4.0 out of 5.0
        Last booking: 45 hours ago
        Pelican Cove Resort & Marina
        3.0 out of 5.0
        Last booking: 45 hours ago
        Chesapeake Beach Resort
        2.5 out of 5.0
        Last booking: 45 hours ago