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Check prices on hotels in Florida Keys

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Featured Florida Keys 4 Star Hotels

See all 848 Properties in Florida Keys
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (3,472 reviews)
Not the last time I hopeThis was our first time staying at the Dewey's house, B&B in general for the first time as well. Excellent room and staff! Will recommend over waldord or any other big resorts! Such an awesome hotel and LT was so great when she greeted us at the door when we first came in. We loved the breakfast ...
Jun 21, 2018

Southernmost Beach Resort$229

Southernmost Beach Resort$229
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (570 reviews)
Beautiful HotelThe hotel facade and hampton's style decorating is perfection, the grounds and facilities excellent. The location of the building that we stayed in was poor and far away from everything, try and avoid Building 4 if you can, access to everything from here is not thought through. The hotel reception ...
Jun 13, 2018
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (318 reviews)
Highly recommendWe only stayed for a short time. Hotel was nice and clean. Staff was great, lots of amenities and right in the middle of everything.
Jun 16, 2018

Margaritaville Key West Resort & Marina$250

Margaritaville Key West Resort & Marina$250
The Perry Hotel Key West

The Perry Hotel Key West

7001 Shrimp Road, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.6 out of 5 (222 reviews)
Better than expectedOff the beaten path but a welcome change of pace with a great atmosphere. Industrial modern feel with great views of the marina. Very comfortable room. Staff friendly and accommodating. Restaraunt on site had an excellent Mahi sandwich. Definitely worth at least one meal while here. Would stay here ...
Jun 15, 2018

The Perry Hotel Key West$161

The Perry Hotel Key West$161
24 North Hotel Key West

24 North Hotel Key West

3820 North Roosevelt Boulevard, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.1 out of 5 (1,241 reviews)
Fair. O.K.Rust running down the shower towel rack can be easily fixed, but is not. Room not as clean as it should be. 3 great hotel staff members at desk. Young man not helpful. Pool area good and outside bar very nice. 1/2 price drinks appreciated (made real price reasonable). Just charge 1/2 prince to drink ...
Jun 4, 2018

24 North Hotel Key West$152

24 North Hotel Key West$152
The Gates Hotel Key West

The Gates Hotel Key West

3824 N Roosevelt Blvd, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (1,257 reviews)
Awesome hotel Free shuttle was awesome but still only a 5-10 min drive if we chose to drive into town ourselves. Room was clean, well decorated, and comfortable. It did have a little bit of a musty smell when we initially walked in but most likely from the humidity. Check in and check out was smooth. Pool and ...
Jun 19, 2018
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
    4.0 out of 5.0
     
     
    4.4 out of 5 (1,555 reviews)
    Wonderful hotel with a beachGreat hotel with a beautiful beach and great amenities. Would definitely return to this resort and recommend it to friends
    Jun 11, 2018

    Pier House Resort & Spa$290

    Pier House Resort & Spa$290
    Casa Marina, A Waldorf Astoria Resort

    Casa Marina, A Waldorf Astoria Resort

    1500 Reynolds Street, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.2 out of 5 (2,198 reviews)
    Classic luxury - modern amenitiesMr. Flagler knew what he was doing when he built the place. We had a king suite beach walkout and stepped right on to the sand. Room was laid out great, friendly staff, nice pool, easy to use water equipment and bikes etc. This is a higher end resort so you will pay for what you use - for example, ...
    May 7, 2018

    Casa Marina, A Waldorf Astoria Resort$268

    Casa Marina, A Waldorf Astoria Resort$268
    The Marker Waterfront Resort Key West

    The Marker Waterfront Resort Key West

    200 William Street, Key West
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.5 out of 5 (990 reviews)
    Very nice resort right next to oceanThis was a great place! Clean and friendly and in a great location to walk everywhere!
    Jun 20, 2018

    The Marker Waterfront Resort Key West$169

    The Marker Waterfront Resort Key West$169
    Tranquility Bay Beachfront Hotel and Resort

    Tranquility Bay Beachfront Hotel and Resort

    2600 Overseas Hwy, Marathon
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     
    4.5 out of 5 (1,136 reviews)
    Beautiful view from any angleSpacious and very clean No contact at all from management staff which was disappointing after 8 days stay Dining was overpriced Facilities were beautiful and lots to see and do in Marathon
    May 3, 2018

    Tranquility Bay Beachfront Hotel and Resort$224

    Tranquility Bay Beachfront Hotel and Resort$224
    Map

    You'll see that you are in fine company with a visit to Florida Keys. Vacationers similar to you have made it one of our top most visited locals the past two years. However, "location, location, location" applies to more than just your vacation destination. When you want to make your next vacation extra special, it's all about where you start each new day.

    Properties as Gorgeous as Florida Keys

    Florida Keys saw thousands of tourists in 2016, and Expedia's comment section boast comments that highlight how fabulous these properties are. When you book a 4-star hotel you can breathe easy knowing that these properties aim to exceed your needs. You'll never have to search for to sustain your exercise routine, an energizing swim, or nice dinner during your stay, thanks to all that these hotels provide. They aim to make their facilities and grounds pleasing from the instant you step onto the property and with every step across their floors. Florida Keys has dozens of wonderful lodgings that make for the ideal holiday.

    Rooms have been fashioned to keep you as comfortable as possible, with amenities like premium bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something else, you can trust the staff will do their best to ensure you continue to be pleased during your stay there. These accommodations are so lovely that you'll regret the day you have to return home.

    Book a 4-Star Hotel in Florida Keys Today!

    A trip to Florida Keys should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are fabulous. Book a 4-star hotel in Florida Keys soon, because several other people are too.