Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


The outset of any trip kicks off with picking a spot. Isle of Palms is a popular choice with guests because of all its local amenities. Location is everything, but that accounts for more than the area you are flying into. Now that you have gotten a feel for this city, it's time you to get to know your home away from home.

Accommodations as Picturesque as the City

Isle of Palms saw its fair share of visitors in the last year. Expedia's comment section provides reviews on which accommodation will satisfy your desires for an incredible stay. When you reserve a 4-star suite you can relax knowing that these properties strive to meet your every need. These hotels strive to make their facilities and grounds pleasing from the moment you step out of your car. You'll never have to search long to sustain your exercise routine, enjoy an energizing spa treatment, or find a delicious breakfast during your stay with all that they provide.

Rooms have been configured to keep you as comfortable as possible, with amenities like designer bathroom products, ultra-comfortable bedding, and in-room tea or coffee. So, lay back and unwind. Moreover, if you find that you are need of something else, you can rest assured the staff will do their best to ensure you stay satisfied during your stay there. These hotels are so nice that you'll regret the day you have to leave.

Reserve a 4-Star Hotel in Isle of Palms Today!

Your vacation to Isle of Palms should be a break from your daily schedule. Your vacation should be all about getting the very most out of your destination. And getting the most often means giving yourself the best. Expedia has 4-star hotels that allow you to do just that. Reserve with Expedia today!

Recently booked 4 Star Hotels in Isle of Palms

Wild Dunes Resort By Destination Hotels
4.0 out of 5.0
Last booking: 10 hours ago
The Palms Oceanfront Hotel
3.5 out of 5.0
Last booking: 11 hours ago
Seaside Inn Oceanfront
2.5 out of 5.0
Last booking: 34 hours ago