Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Jacksonville 4 Star Hotels

See all 403 Hotels in Jacksonville
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

225 E Coastline Dr, Jacksonville
4.0 out of 5.0
4.3 out of 5 (1,504 reviews)
HYATTTHE HOTEL WAS FIND, BUT THE AREA WASNT GOOD. NOTHING VERY CLOSE AND THE AREA DIDNT SEEM ALL THAT SAFE
  Dec 8, 2017

$99

$99
Omni Jacksonville Hotel

Omni Jacksonville Hotel

245 Water St, Jacksonville
4.5 out of 5.0
4.3 out of 5 (1,454 reviews)
Great!! Would recommend to anyone looking for a good hotel at the right price.
  Dec 6, 2017

$81

$81
Villas of Amelia Island Plantation

Villas of Amelia Island Plantation

39 Beach Lagoon Road, Fernandina Beach
4.5 out of 5.0
4.2 out of 5 (532 reviews)
We had a great view of the ocean and would highly recommend this resort to others
  Dec 12, 2017

$101

$101
DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport

2101 Dixie Clipper Dr, Jacksonville
4.0 out of 5.0
4.2 out of 5 (554 reviews)
Nice hotel close to a lot of restaurants It was a great experience staying at the Double Tree. I throughly enjoyed my overnight stay there
  Dec 12, 2017

$89

$89
Omni Amelia Island Plantation Resort

Omni Amelia Island Plantation Resort

39 Beach Lagoon Road, Fernandina Beach
4.5 out of 5.0
4.4 out of 5 (813 reviews)
Beautiful hotel on beach. Oh, we are so going there again. Spent one night to celebrate 17 yr Anniversary! This resort is gorgeous. Didn't have time to see everything. Resort is on the beach. We didn't bring our kids but noticed how kid/family friendly the Resort is. Very clean! Room was awesome! Staff was awesome!!!
  Dec 4, 2017

$169

$169
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

9300 Baymeadows Road, Jacksonville
4.0 out of 5.0
4.0 out of 5 (930 reviews)
Nice clean n great customer service It's was a great experience, I love it n I will visit again soon, great people n customer service
  Dec 8, 2017

$125

$125
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

10605 Deerwood Park Blvd, Jacksonville
4.0 out of 5.0
4.5 out of 5 (109 reviews)
Sheraton JacksonvilleGreat location and the hotel seems brand new. Everything is clean, beds are comfortable and the staff were very professsional and helpful. I will stay again the next time I visit Jacksonville.
  Dec 10, 2017

$93

$93
Hotel Indigo Jacksonville-Deerwood Park

Hotel Indigo Jacksonville-Deerwood Park

9840 Tapestry Park Cir, Jacksonville
4.0 out of 5.0
4.7 out of 5 (792 reviews)
Just there overnight and everything was quite nice!!!
  Dec 2, 2017

$105

$105
Sawgrass Marriott Golf Resort & Spa

Sawgrass Marriott Golf Resort & Spa

1000 PGA Tour Blvd, Ponte Vedra Beach
4.5 out of 5.0
4.3 out of 5 (618 reviews)
Great hotel - very clean, great staff. Easy check-in, food was great as well.
  Sep 18, 2017

$110

$110
Crowne Plaza Hotel Jacksonville Airport/I-95N

Crowne Plaza Hotel Jacksonville Airport/I-95N

14670 Duval Rd, Jacksonville
4.0 out of 5.0
4.1 out of 5 (406 reviews)
Nice. But there was still dirty towels in the room. The closet was a bit torn up, but the rest of the room was nice. Beds were very comfortable.
  Dec 12, 2017

$99

$99
Map

The get-go of any well-deserved holiday starts with picking a destination. Jacksonville has become a popular destination with guests because of everything it offers. However, "location, location, location" applies to more than just your vacation destination. When you want to make a trip extra special, it's all about where you stay each night.

Hotels as Stunning as the City

Jacksonville saw hundreds of guests just last year, and Expedia's comment section contains tips to help you select the room that is optimal for your holiday. The hotels found here aim to make your vacation as enjoyable as your nights spent exploring Jacksonville. These hotels work to make their facilities and grounds inviting from the second you step out of your car. You won't have to search to find a gourmet dinner, to sustain your workout routine, or for a refreshing spa treatment during your vacation with all they provide. Jacksonville has dozens of wonderful hotels that make for the ideal escape.

Rooms have been fashioned to keep you as cozy as possible, with amenities like specially designed bathroom products, premium bedding, and in-room coffee or tea. So, sit back and decompress. Moreover, if you find yourself in need of anything more, you can trust the staff will work their hardest to ensure you continue to be happy during your time. These accommodations are so lovely that you'll regret the day you have to go back home.

Reserve a 4-Star Hotel in Jacksonville Today!

A getaway to Jacksonville should be one that you'll recall for years to come, and booking a 4-star hotel will help create memories that are fantastic. Review our great selection of 4-star hotels in Jacksonville that will bring your vacation to the next level.

Recently booked 4 Star Hotels in Jacksonville

Motel 6 Jacksonville - Orange Park
2.5 out of 5.0
Last booking: 2 minutes ago
Extended Stay America - Jacksonville - Deerwood Park
3.0 out of 5.0
Last booking: 8 minutes ago
Four Points by Sheraton Jacksonville Beachfront
3.5 out of 5.0
Last booking: 12 minutes ago
Stars Rest Inn
2.0 out of 5.0
Last booking: 15 minutes ago
Ramada Jacksonville Hotel and Conference Center
3.5 out of 5.0
Last booking: 16 minutes ago
Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 out of 5.0
Last booking: 31 minutes ago
Holiday Inn Hotel & Suites Orange Park
3.5 out of 5.0
Last booking: 34 minutes ago
The Inn At Mayo Clinic
3.5 out of 5.0
Last booking: 38 minutes ago
Hyatt Place Jacksonville Airport
3.5 out of 5.0
Last booking: 39 minutes ago