Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Jacksonville 4 Star Hotels

See all 563 Hotels in Jacksonville
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

225 E Coastline Dr, Jacksonville
4.0 out of 5.0
4.3 out of 5 (1,516 reviews)
Nice PlaceStaff is unbelievably professional and courteous. Rooms are clean and comfortable. My only complaint would be the price. I was a bit dissapointed when (after paying more than enough for my room) I was charged extra for a continental breakfast and parking. Other than that it was excellent.
  Feb 16, 2018

$129

$129
Omni Jacksonville Hotel

Omni Jacksonville Hotel

245 Water St, Jacksonville
4.0 out of 5.0
4.3 out of 5 (1,460 reviews)
Overnight stay to see show next door!Outstanding customer service from beginning to end. Our room was very clean and well appointed. We enjoyed a light dinner in the lobby bar. Breakfast came through room service as ordered and on ttc
  Feb 10, 2018

$130

$130
Lexington Hotel & Conference Center - Jacksonville Riverwalk

Lexington Hotel & Conference Center - Jacksonville Riverwalk

1515 Prudential Dr, Jacksonville
4.0 out of 5.0
3.0 out of 5 (1,354 reviews)
Nice hotel, clean and convenient to downtownHotel was clean and very comfortable. House keeping was a alittle confused with restocking coffee each day. The front desk was very helpful. There was construction in the lobby but no noise. The rooms were updated and very nice.
  Feb 14, 2018

$119

$119
Omni Amelia Island Plantation Resort

Omni Amelia Island Plantation Resort

39 Beach Lagoon Road, Fernandina Beach
4.0 out of 5.0
4.4 out of 5 (833 reviews)
The staff are so friendly and amazing. They were always willing to help and went above and beyond to make sure we enjoyed our stay! The food was delicious and the property was beautiful. The staff at the spa were very attentive and we were treated so wonderful. I'm already planning when I want to ...
  Feb 12, 2018

$233

$233
DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront

1201 Riverplace Boulevard, Jacksonville
4.0 out of 5.0
3.9 out of 5 (1,049 reviews)
Clean room clean balcony with no nosey neighbors. I've been here veggie m before so I knew what to expect thats why we choose too stay here and especially because Ruth's Chris is right down stairs. I would definately recommend people to stay here.
  Jan 28, 2018

$134

$134
DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport

2101 Dixie Clipper Dr, Jacksonville
4.0 out of 5.0
4.2 out of 5 (578 reviews)
Nice Hotel near the AirportThis was a nice hotel. The lobby was clean and attractive. It appeared to have a lot of guests. This was the reason one of my rooms was not available until late and we didn't check in until around 7 :00 pm. We were very tried and just wanted to rest. One room was nice but the third room had a smell ...
  Feb 19, 2018

$114

$114
Icon Hotel Jacksonville

Icon Hotel Jacksonville

4700 Salisbury Rd, Jacksonville
4.0 out of 5.0
4.0 out of 5 (1,770 reviews)
Nice Hotel, Somewhat Dated FacilitiesThe hotel is going through renovations, so expect things like not having both elevators available and somewhat noisy during the day (but not after 5 pm). But all in all, the staff is doing the best they can. The good: The room was very clean with no bad odors. Being on the 6th floor made the room ...
  Feb 12, 2018

$91

$91
Villas of Amelia Island Plantation

Villas of Amelia Island Plantation

39 Beach Lagoon Road, Fernandina Beach
4.0 out of 5.0
4.2 out of 5 (558 reviews)
Beautiful room with a viewStaff was excellent. Bed was extremely comfortable. Resort was top-notch. Would go again.
  Jan 8, 2018

$149

$149
Sawgrass Marriott Golf Resort & Spa

Sawgrass Marriott Golf Resort & Spa

1000 PGA Tour Blvd, Ponte Vedra Beach
4.0 out of 5.0
4.3 out of 5 (625 reviews)
Everything was as expected, pub food was good and valet guys
  Feb 18, 2018

$279

$279
Club Continental

Club Continental

2143 Astor Street, Orange Park
4.0 out of 5.0
4.5 out of 5 (110 reviews)
Nice but cold!During my stay the weather was damp and cold. Would have been nice to have heat. Had to wear two layers of othing in room w a coat!
  Feb 15, 2018

$115

$115
Map

The get-go of any well-deserved holiday starts with picking a destination. Jacksonville has become a popular destination with guests because of everything it offers. However, "location, location, location" applies to more than just your vacation destination. When you want to make a trip extra special, it's all about where you stay each night.

Hotels as Stunning as the City

Jacksonville saw hundreds of guests just last year, and Expedia's comment section contains tips to help you select the room that is optimal for your holiday. The hotels found here aim to make your vacation as enjoyable as your nights spent exploring Jacksonville. These hotels work to make their facilities and grounds inviting from the second you step out of your car. You won't have to search to find a gourmet dinner, to sustain your workout routine, or for a refreshing spa treatment during your vacation with all they provide. Jacksonville has dozens of wonderful hotels that make for the ideal escape.

Rooms have been fashioned to keep you as cozy as possible, with amenities like specially designed bathroom products, premium bedding, and in-room coffee or tea. So, sit back and decompress. Moreover, if you find yourself in need of anything more, you can trust the staff will work their hardest to ensure you continue to be happy during your time. These accommodations are so lovely that you'll regret the day you have to go back home.

Reserve a 4-Star Hotel in Jacksonville Today!

A getaway to Jacksonville should be one that you'll recall for years to come, and booking a 4-star hotel will help create memories that are fantastic. Review our great selection of 4-star hotels in Jacksonville that will bring your vacation to the next level.

Recently booked 4 Star Hotels in Jacksonville

Residence Inn by Marriott Amelia Island
3.5 out of 5.0
Last booking: 5 minutes ago
Country Inn & Suites by Radisson, Jacksonville I-95 South, FL
3.0 out of 5.0
Last booking: 5 minutes ago
La Quinta Inn & Suites Jacksonville Mandarin
3.0 out of 5.0
Last booking: 5 minutes ago
Jacksonville Plaza Hotel & Suites
2.5 out of 5.0
Last booking: 7 minutes ago
Courtyard by Marriott Mayo Clinic/Jacksonville
3.0 out of 5.0
Last booking: 9 minutes ago
Stars Rest Inn
2.5 out of 5.0
Last booking: 18 minutes ago
Hometown Inn & Suites Jacksonville - Butler Blvd./Southpoint
2.5 out of 5.0
Last booking: 22 minutes ago
Icon Hotel Jacksonville
4.0 out of 5.0
Last booking: 28 minutes ago
La Quinta Inn & Suites Jacksonville Butler Blvd
3.0 out of 5.0
Last booking: 42 minutes ago