Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Knoxville 4 Star Hotels

See all 160 Hotels in Knoxville
The Tennessean Personal Luxury Hotel

The Tennessean Personal Luxury Hotel

531 Henley Street, Knoxville
    4.0 out of 5.0
     
     
    4.8 out of 5 (97 reviews)
    Awesome Service - made us feel right at home After travelling for most of the day it was nice to come to a hotel where everyone was so helpful! They recommended an excellent Italian restaurant within walking distance as we were tired and hungry. Room was nice and clean - bedding was soft and awesome. Excellent Breakfast in the 2nd floor lounge ...
    Apr 23, 2018

    The Tennessean Personal Luxury Hotel$199

    The Tennessean Personal Luxury Hotel$199
    Cook Loft

    Cook Loft

    722 S Gay St, Knoxville
      4.0 out of 5.0
       
       
      5.0 out of 5 (1 reviews)
      Knoxville's best meeting placeI and 8 other friends met in Knoxville, TN to celebrate the visit of long-not-seen English friend who was visiting. Since one of the group was a gourmet chef, the Cook Loft was a natural choice. The spacious and well equipped kitchen was the center of interest as we sat and watched him prepare the ...
      Aug 12, 2011

      Cook Loft$660

      Cook Loft$660

      The outset of any vacation kicks off with selecting a spot. Knoxville has been a popular local with guests because it offers so much to see and do. Location is everything, but that accounts for more than the town you are flying into. Now that you got a feeling for this city, it's time you to learn a little more about your home away from home.

      Lodgings as Scenic as Knoxville

      Knoxville saw hundreds of travelers in 2016, and Expedia's review section contains tips that highlight how incredible these accommodations are. The hotels found here strive to make your vacation as pleasant as your days spent out in Knoxville. These hotels strive to make the grounds and facilities hospitable from the moment you step out of your car. You will never need to go far to find a delectable breakfast, to sustain your workout schedule, or for an energizing spa treatment during your visit with all that they provide. Knoxville has dozens of fantastic accommodations that offer the ideal getaway.

      Rooms have been furnished to keep you as comfortable as possible, with amenities like premium bedding, in-room tea or coffee, and specially designed bathroom products. So, lay back and decompress. Moreover, if you find that you're need of anything else, you can be confident the staff will work their best to ensure you remain happy during your time. These hotels are so lovely that you'll regret the day you have to return home.

      Reserve a 4-Star Hotel in Knoxville Today!

      A getaway to Knoxville should be a break from your everyday routine. Peruse Expedia's great selection of 4-star hotels in Knoxville that will take your getaway to the next level.

      Recently booked 4 Star Hotels in Knoxville

      Red Roof Inn PLUS+ & Suites Knoxville West – Cedar Bluff
      2.5 out of 5.0
      Last booking: 18 minutes ago
      Comfort Suites Knoxville West - Farragut
      2.5 out of 5.0
      Last booking: 24 minutes ago
      Microtel Inn by Wyndham Knoxville
      2.0 out of 5.0
      Last booking: 1 hour ago
      Country Inn & Suites by Radisson, Knoxville Airport, TN
      2.5 out of 5.0
      Last booking: 2 hours ago
      Clarion Inn & Suites Near Downtown
      2.5 out of 5.0
      Last booking: 3 hours ago
      Hilton Garden Inn University/Knoxville
      3.0 out of 5.0
      Last booking: 3 hours ago
      Country Inn & Suites by Radisson, Knoxville West, TN
      2.5 out of 5.0
      Last booking: 4 hours ago
      Sleep Inn North
      2.5 out of 5.0
      Last booking: 4 hours ago
      La Quinta Inn & Suites Knoxville Central Papermill
      2.5 out of 5.0
      Last booking: 4 hours ago