Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Knoxville 4 Star Hotels

See all 160 Hotels in Knoxville
The Tennessean Personal Luxury Hotel

The Tennessean Personal Luxury Hotel

531 Henley Street, Knoxville
    4.0 out of 5.0
     
     
    4.8 out of 5 (96 reviews)
    FaultlessExcellent hotel, faultless experience from start to finish. The staff were absolutely amazing and nothing was too much trouble. Rooms were of a good size, clean, tastefully decorated and high quality amenities (molton brown) were provided. The hotel itself is excellent, boutique (which I prefer) ...
    Mar 28, 2018

    The Tennessean Personal Luxury Hotel$219

    The Tennessean Personal Luxury Hotel$219
    Cook Loft

    Cook Loft

    722 S Gay St, Knoxville
      4.0 out of 5.0
       
       
      5.0 out of 5 (1 reviews)
      Knoxville's best meeting placeI and 8 other friends met in Knoxville, TN to celebrate the visit of long-not-seen English friend who was visiting. Since one of the group was a gourmet chef, the Cook Loft was a natural choice. The spacious and well equipped kitchen was the center of interest as we sat and watched him prepare the ...
      Aug 12, 2011

      Cook Loft$660

      Cook Loft$660

      The outset of any vacation kicks off with selecting a spot. Knoxville has been a popular local with guests because it offers so much to see and do. Location is everything, but that accounts for more than the town you are flying into. Now that you got a feeling for this city, it's time you to learn a little more about your home away from home.

      Lodgings as Scenic as Knoxville

      Knoxville saw hundreds of travelers in 2016, and Expedia's review section contains tips that highlight how incredible these accommodations are. The hotels found here strive to make your vacation as pleasant as your days spent out in Knoxville. These hotels strive to make the grounds and facilities hospitable from the moment you step out of your car. You will never need to go far to find a delectable breakfast, to sustain your workout schedule, or for an energizing spa treatment during your visit with all that they provide. Knoxville has dozens of fantastic accommodations that offer the ideal getaway.

      Rooms have been furnished to keep you as comfortable as possible, with amenities like premium bedding, in-room tea or coffee, and specially designed bathroom products. So, lay back and decompress. Moreover, if you find that you're need of anything else, you can be confident the staff will work their best to ensure you remain happy during your time. These hotels are so lovely that you'll regret the day you have to return home.

      Reserve a 4-Star Hotel in Knoxville Today!

      A getaway to Knoxville should be a break from your everyday routine. Peruse Expedia's great selection of 4-star hotels in Knoxville that will take your getaway to the next level.

      Recently booked 4 Star Hotels in Knoxville

      Best Western Knoxville Suites - Downtown
      2.5 out of 5.0
      Last booking: 6 minutes ago
      Comfort Suites Airport
      2.5 out of 5.0
      Last booking: 11 minutes ago
      La Quinta Inn & Suites Knoxville Airport
      2.5 out of 5.0
      Last booking: 17 minutes ago
      Days Inn Lenoir City TN
      2.0 out of 5.0
      Last booking: 24 minutes ago
      Motel 6 Knoxville North
      2.0 out of 5.0
      Last booking: 28 minutes ago
      Extended Stay America - Knoxville - Cedar Bluff
      2.5 out of 5.0
      Last booking: 30 minutes ago
      Holiday Inn Express Hotel & Suites Knoxville West -Papermill
      2.5 out of 5.0
      Last booking: 42 minutes ago
      Baymont Inn & Suites Knoxville/Cedar Bluff
      2.5 out of 5.0
      Last booking: 54 minutes ago
      La Quinta Inn & Suites Knoxville Central Papermill
      2.5 out of 5.0
      Last booking: 55 minutes ago