Photo by ML Terry
Find 4 Star Hotels in Lake Nona, FL from $100
Upfront pricingOur total price for your stay includes taxes and fees
Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
Be pickySearch almost a million properties worldwide
Check availability on Lake Nona 4 Star Hotels
Our top choices for Lake Nona 4-star hotels
9.4 out of 10, Exceptional, (4,111 reviews)
"Thank you for a great stay"
Julia
$229 nightly
The price is $258
Apr 26 - Apr 27
Total with taxes and fees
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Sheraton Vistana Resort Villas, Lake Buena Vista/OrlandoOrlando
9.2 out of 10, Wonderful, (5,163 reviews)
"The best place to stay "
Rosario
$123 nightly
The price is $139
May 5 - May 6
Total with taxes and fees
9.2 out of 10, Wonderful, (2,090 reviews)
"Beautiful hotel and very friendly staff"
Amy
$211 nightly
The price is $238
Apr 23 - Apr 24
Total with taxes and fees
Westgate Lakes Resort & Spa Universal Studios Area
Westgate Lakes Resort & Spa Universal Studios AreaOrlando
8.4 out of 10, Very Good, (6,241 reviews)
"Great resort and location "
Christine
$127 nightly
The price is $143
Apr 26 - Apr 27
Total with taxes and fees
9.0 out of 10, Wonderful, (4,163 reviews)
"Love this place, third time with kids in past year."
Jayme
$211 nightly
The price is $238
May 7 - May 8
Total with taxes and fees
9.0 out of 10, Wonderful, (4,156 reviews)
"Great place to stay"
Candise
$111 nightly
The price is $125
May 4 - May 5
Total with taxes and fees
Courtyard by Marriott Lake Buena Vista at Vista Centre
Courtyard by Marriott Lake Buena Vista at Vista CentreOrlando
8.2 out of 10, Very Good, (1,530 reviews)
"Good location, friendly staff. "
Catherine
$89 nightly
The price is $100
May 4 - May 5
Total with taxes and fees
Sheraton Vistana Villages Resort Villas, I-Drive/Orlando
Sheraton Vistana Villages Resort Villas, I-Drive/OrlandoInternational Drive District
9.2 out of 10, Wonderful, (3,280 reviews)
"Excellent stay"
TEISHA
$100 nightly
The price is $113
May 12 - May 13
Total with taxes and fees
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Lake Nona.
Waldorf Astoria Orlando - An Official Walt Disney World® Hotel
14200 Bonnet Creek Resort Lane Orlando FL
$435 nightly
The price is $489 total per night from May 10 to May 11
$489 total
May 10 - May 11
Total with taxes and fees
9.2/10 Wonderful! (496 reviews)
Still don't see what you're looking for?
See all properties in Lake Nona.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Lake Nona Hotel Reviews
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
6/10 Okay
Frequently asked questions
Explore a world of travel with Expedia
- Orlando Hotels
- Hotels near Orlando Intl.
- Hotels near Nemours Children's Hospital
- 5 Star Hotels in Lake Nona Medical City
- 3 Star Hotels in Lake Nona Medical City
- Hotels near Lake Nona Medical City
- Hotels with Free Airport Shuttle in Lake Nona Medical City
- Hotels with Kitchenettes in Lake Nona Medical City
- Hotels with Restaurants in Lake Nona Medical City
- Pet-Friendly Hotels in Lake Nona Medical City
- Extended Stay Hotels in Lake Nona Medical City
- Hotels with Laundry Facilities in Lake Nona Medical City
- Extended Stay America Hotels in Lake Nona Medical City
- Hyatt Hotels in Lake Nona Medical City
- Luxury Hotels in Lake Nona Medical City
- Golf Hotels in Lake Nona Medical City
- Hotels with a Pool in Lake Nona Medical City
- Hotels near VA Medical Center at Lake Nona
- Hotels near University of Central Florida College of Medicine
- Hotels near Eagle Creek Golf Club
- 5 Star Hotels in Lake Hart
- Hotels near Walt Disney World® Resort
- Hotels near Lake Hart
- Hotels near David Leadbetter Golf Academy
- Southeast Orlando Hotels
- Flights to Orlando
- Flights from New York (JFK) to Orlando (MCO)
- Flights to Florida
- Flights from Boston (BOS) to Orlando (MCO)
- Flights from Philadelphia (PHL) to Orlando (MCO)
- Flights from Chicago (ORD) to Orlando (MCO)
- Flights from Detroit (DTW) to Orlando (MCO)
- Flights from Dallas (DFW) to Orlando (MCO)
- Flights from Los Angeles (LAX) to Orlando (MCO)
- Flights from Minneapolis (MSP) to Orlando (MCO)
- Flights from Raleigh (RDU) to Orlando (MCO)
- Flights from Miami (MIA) to Orlando (MCO)
- Flights from Charlotte (CLT) to Orlando (MCO)
- Flights from Hartford (BDL) to Orlando (MCO)
- Flights from Cleveland (CLE) to Orlando (MCO)
- Flights from Baltimore (BWI) to Orlando (MCO)
- Flights from Washington (DCA) to Orlando (MCO)
- Flights from Houston (HOU) to Orlando (MCO)
- Flights from Denver (DEN) to Orlando (MCO)
- Flights from Pittsburgh (PIT) to Orlando (MCO)
- Flights from Orlando Intl.
- Flights from Nashville (BNA) to Orlando (MCO)
- Flights from Indianapolis (IND) to Orlando (MCO)
- Flights from Cincinnati (CVG) to Orlando (MCO)
- Flights from Fort Lauderdale (FLL) to Orlando (MCO)
- Flights from Seattle (SEA) to Orlando (MCO)
- Flights from Phoenix (PHX) to Orlando (MCO)
- Flights from Columbus (CMH) to Orlando (MCO)
- Flights from Milwaukee (MKE) to Orlando (MCO)
- Flights from San Francisco (SFO) to Orlando (MCO)
- Flights from Salt Lake City (SLC) to Orlando (MCO)
- Flights from Richmond (RIC) to Orlando (MCO)
- Flights from St. Louis (STL) to Orlando (MCO)
- Flights from Buffalo (BUF) to Orlando (MCO)
- Flights from Providence (PVD) to Orlando (MCO)
- Flights from Syracuse (SYR) to Orlando (MCO)
- Flights from Austin (AUS) to Orlando (MCO)
- Flights from Las Vegas (LAS) to Orlando (MCO)
- Flights from Kansas City (MCI) to Orlando (MCO)
- Flights from New York (LGA) to Orlando (MCO)
- Flights from New Orleans (MSY) to Orlando (MCO)
- Flights from Memphis (MEM) to Orlando (MCO)
- Flights from New York (NYC) to Orlando (MCO)
- Flights from San Juan (SJU) to Orlando (MCO)
- Flights from Albany (ALB) to Orlando (MCO)
- Flights from Grand Rapids (GRR) to Orlando (MCO)
- Flights from Tampa (TPA) to Orlando (MCO)
- Flights from San Diego (SAN) to Orlando (MCO)
- Flights from Portland (PDX) to Orlando (MCO)
- Flights from Norfolk (ORF) to Orlando (MCO)
- Flights from Pensacola (PNS) to Orlando (MCO)
- Flights from San Antonio (SAT) to Orlando (MCO)
- Flights from Louisville (SDF) to Orlando (MCO)
- Jetblue Airways New York (JFK) to Orlando (MCO) flights
- Flights from Harrisburg (MDT) to Orlando (MCO)
- Flights from Manchester (MHT) to Orlando (MCO)
- Flights from Rochester (ROC) to Orlando (MCO)
- Walt Disney World® Resort
- Nemours Children's Hospital
- Visit Lake Nona Medical City
- Lake Nona Medical City Vacations
- Va Medical Center at Lake Nona
- University of Central Florida College of Medicine
- Orlando Vacations
- Eagle Creek Golf Club
- Sanford-Burnham Medical Research Institute
- Visit Lake Hart
- David Leadbetter Golf Academy