--- title: "The Best 4 Star Hotels in Mytilene from $56 | Expedia" description: "Find the best 4 Star Hotels in Mytilene in 2026. Compare room rates, hotel reviews and availability. Most hotels are fully refundable." canonical: "https://www.expedia.com/4Star-Mytilene-Hotels.s40-0-d6062865.Travel-Guide-Filter-Hotels" language: en-US market: US currency: USD prices_as_of: 2026-11-14T13:35:18Z --- Plan your trip - [Mytilene Travel Guide](https://www.expedia.com/Mytilene.dx6062865) - [Hotels in Mytilene](https://www.expedia.com/Mytilene-Hotels.d6062865.Travel-Guide-Hotels) - [Flights to Mytilene](https://www.expedia.com/Cheap-Flights-To-Mytilene.d6062865.Travel-Guide-Flights) - [Things to do in Mytilene](https://www.expedia.com/Things-To-Do-In-Mytilene.d6062865.Travel-Guide-Activities) - [Car Rentals in Mytilene](https://www.expedia.com/Car-Rentals-In-Mytilene.d6062865.Car-Rental-Guide) - [Mytilene Vacation Packages](https://www.expedia.com/Mytilene.d6062865.Destination-Travel-Guides) - [Vacation Rentals in Mytilene](https://www.expedia.com/Mytilene-Vacation-Rentals.d6062865.Travel-Guide-VacationRentals) # Find 4 Star Hotels in Mytilene from $56 ![A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.](https://images.trvl-media.com/place/6062865/1aa72491-3521-42d6-9b59-0b2ad0423bfb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ### Upfront pricing Our total price for your stay includes taxes and fees ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) ### Be picky Search almost a million properties worldwide ## Check prices for these dates [Check prices for these dates, December 14 – 15, 2026](https://www.expedia.com/Hotel-Search?regionId=6062865&startDate=2026-12-14&endDate=2026-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&star=40) [View in a map](https://www.expedia.com/Hotel-Search?regionId=6062865&stayLength=1&daysInFuture=30&pwaOverlay=map) ## Our top choices for Mytilene 4-star hotels ### [1\. Theofilos Paradise Boutique Hotel](https://www.expedia.com/Lesvos-Hotels-Theofilos-Paradise-Boutique-Hotel.h12319222.Hotel-Information) ![A buffet with various food items including fruits, vegetables, and desserts.](https://images.trvl-media.com/lodging/13000000/12320000/12319300/12319222/a275125a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lesvos - Guest rating: 9.6/10 (Exceptional, 176 reviews) - Price: $109 nightly, $123 total, Nov 22 - Nov 23, Total with taxes and fees, for Our top choices for Mytilene 4-star hotels - Review: Staff was nice. Large breakfast spread. Location is great., by Caroline ### [2\. Loriet Hotel](https://www.expedia.com/Lesvos-Hotels-Loriet-Hotel.h11098314.Hotel-Information) ![A large stone building with a central entrance, flanked by palm trees and a stone pathway leading to the entrance.](https://images.trvl-media.com/lodging/12000000/11100000/11098400/11098314/1cb8d2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lesvos - Guest rating: 8.4/10 (Very good, 96 reviews) - Price: $63 nightly, $72 total, Dec 14 - Dec 15, Total with taxes and fees, for Our top choices for Mytilene 4-star hotels - Review: A very nice and comfortable hotel🙏, by Fadime ### [3\. Heliotrope Hotels](https://www.expedia.com/Lesvos-Hotels-Heliotrope-Hotels.h890395.Hotel-Information) ![A hotel with a swimming pool, outdoor seating, and a view of the sea.](https://images.trvl-media.com/lodging/1000000/900000/890400/890395/7165700e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lesvos - Guest rating: 8.6/10 (Excellent, 203 reviews) - Price: $80 nightly, $91 total, Nov 17 - Nov 18, Total with taxes and fees, for Our top choices for Mytilene 4-star hotels - Review: The breakfast was so rich and delicious. Rooms, by Ufuk ### [4\. Zaira Hotel](https://www.expedia.com/Lesvos-Hotels-Zaira-Hotel.h101024199.Hotel-Information) ![A stone building with a red roof, surrounded by trees and a grassy lawn.](https://images.trvl-media.com/lodging/102000000/101030000/101024200/101024199/f62afddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lesvos ### [5\. Aeolian Gaea Hotel](https://www.expedia.com/Lesvos-Hotels-Aeolian-Gaea-Hotel.h3480272.Hotel-Information) ![A hotel with a swimming pool, outdoor seating, and a view of the surrounding landscape.](https://images.trvl-media.com/lodging/4000000/3490000/3480300/3480272/960196bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lesvos - Guest rating: 9.6/10 (Exceptional, 8 reviews) - Review: Great place to stay. Friendly service and very good facilities. Would definitely stay there again. , by George ### [6\. Pyrgos Sofokleous](https://www.expedia.com/Lesvos-Hotels-PYRGOS-SOFOKLEOYS.h46270748.Hotel-Information) ![A hotel lobby with a marble staircase, a reception desk, and a view of the interior.](https://images.trvl-media.com/lodging/47000000/46280000/46270800/46270748/ffd0dbe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lesvos ## Top Mytilene Hotel Reviews ### [Akti Vigla Premium](https://www.expedia.com/Lesvos-Hotels-Akti-Vigla-Premium.h119892175.Hotel-Information) ![A balcony with a view of the ocean, featuring a sofa, a table, and a railing.](https://images.trvl-media.com/lodging/120000000/119900000/119892200/119892175/b889cbac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lesvos - Review: Breakfast was fantastic and we loved the engineering of the patio doors. They tilt and open, by Rebecca, September 14, 2026, rated 10/10 Excellent ### [Galazio Asteri I](https://www.expedia.com/Lesvos-Hotels-Galazio-Asteri-I.h21240031.Hotel-Information) ![A pool area with lounge chairs and umbrellas, surrounded by greenery and a clear sky.](https://images.trvl-media.com/lodging/22000000/21250000/21240100/21240031/e2e0c517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Location: Lesvos - Review: From the moment we entered the gate, our experience at Galazio Asteri 1 was the most welcoming and relaxing stay we have ever had in our travels. Dimitris and Michaela are two of the kindest people you will ever meet and make you feel like family. The hotel apartment was well furnished and impeccably clean. The beds are super comfortable and kitchen has everything you need when you want to do your own cooking. The swimming pool has four distinct water jet features, the best being the "jet..., by Linda, August 25, 2022, rated 10/10 Excellent ### [Theofilos Paradise Boutique Hotel](https://www.expedia.com/Lesvos-Hotels-Theofilos-Paradise-Boutique-Hotel.h12319222.Hotel-Information) ![A buffet with various food items including fruits, vegetables, and desserts.](https://images.trvl-media.com/lodging/13000000/12320000/12319300/12319222/a275125a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: 7, Skra str, Hatzidimitriou Park, Lesvos, 81100, GR - Location: Lesvos - Star rating: 4/5 - Guest rating: 9.6/10 (176 reviews) - Review: The room was impeccable. The staff were courteous enough to let us check in a few hours early after a long trip., by Micaela, January 29, 2026, rated 10/10 Excellent ### [Heliotrope Hotels](https://www.expedia.com/Lesvos-Hotels-Heliotrope-Hotels.h890395.Hotel-Information) ![A hotel with a swimming pool, outdoor seating, and a view of the sea.](https://images.trvl-media.com/lodging/1000000/900000/890400/890395/7165700e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Varia, Lesvos, Lesvos Island, 81100, GR - Location: Lesvos - Star rating: 4/5 - Guest rating: 8.6/10 (203 reviews) - Review: a fine hotel, recently refurbished, about an 7 euro ride from the aiport and a 16 euro ride to the center of town. bus right across the street runs about every hour (2 or 3-hour intervals on saturday and sunday), and does not run much after 8:30 at night. breakfast was intruiging: the only place i've ever seen an authentic greek coffee maker (with the hot sand) which requires the long instrument, and local sheep butter. as long as the distance from the port does not bother you, this is your..., by mike, October 8, 2012, rated 10/10 Excellent ### [Loriet Hotel](https://www.expedia.com/Lesvos-Hotels-Loriet-Hotel.h11098314.Hotel-Information) ![A large stone building with a central entrance, flanked by palm trees and a stone pathway leading to the entrance.](https://images.trvl-media.com/lodging/12000000/11100000/11098400/11098314/1cb8d2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) - Address: Vareia, Mitilene, Lesvos, Lesvos Island, 81100, GR - Location: Lesvos - Star rating: 4/5 - Guest rating: 8.4/10 (96 reviews) - Review: Our vacation at the Loriet Hotel in Mithilini was amazing. Everything was perfect. We really had very good time in there. Thanks for the hospitality and the hygiene conditions. Having new plans for coming back again., by Melisa, June 27, 2026, rated 10/10 Excellent ## Find out more about Mytilene The preparation of any trip kicks off with deciding on a destination. Mytilene has been a popular option with guests because it offers so much to do. However, "location, location, location" applies to more than just what city where your plane lands. When you want a journey that is amazing from start to finish, you need the perfect place to stay. ### Accommodations as Beautiful as the City Mytilene saw its fair share of visitors in the last year. Our review section contains reviews that will assist you in narrowing down your pick. The resorts found here aim to make your stay as pleasant as your days and evenings out in Mytilene. These hotels aim to make their grounds and facilities hospitable during your visit. You will never have to go far for a delicious meal, a refreshing spa treatment, or to sustain your exercise routine. Rooms have been designed to keep you as comfortable as possible, with amenities like in-room tea or coffee, specially designed bathroom products, and, premium bedding. So, sit back and relax. Moreover, if you find yourself in need of something further, you can rest easy the staff will try their hardest to ensure you remain happy during your time. These properties are so nice that you'll regret the day you have to fly back home. ### Reserve a 4-Star Hotel in Mytilene Today! A trip to Mytilene should be one where you won't have to worry about the little things. Expedia will get inexpensive rates on world-class accommodations to take your getaway to the next level. ## Frequently Asked Questions ### What are the best 4-star hotels in Mytilene? Look forward to 4-star hotel comfort at [Theofilos Paradise Boutique Hotel](https://www.expedia.com/Lesvos-Hotels-Theofilos-Paradise-Boutique-Hotel.h12319222.Hotel-Information). Ranked highly by many of our guests, it offers concierge services and treatment rooms. Also check out [Porto Lesvos](https://www.expedia.com/Lesvos-Hotels-Porto-Lesvos.h13234143.Hotel-Information). Concierge services and complimentary breakfast make this escape another leading pick in Mytilene. ### How much does it cost to stay in a 4-star hotel in Mytilene? To lock in a 4-star hotel in Mytilene that matches your budget, make use of Expedia's sort and search filters. Check out what's available during your getaway dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first. - Search for the lowest price from $56 ### What's the difference between 5-star and 4-star hotels in Mytilene? Offering a welcoming traveler experience and upmarket surroundings, 4-star hotels are a great option for your Mytilene vacation. These kinds of accommodations generally feature lots of useful amenities that make it a breeze to kick back and relax — think 24-hour room service, restaurants and pools. Or enjoy even more lavishness at a 5-star hotel designed to pamper with high-end perks and amenities. Full-service health clubs, oversized bathrooms and world-class dining are typically featured at these plush retreats. ### Does Mytilene have any 4-star all-inclusive resorts? One of the quickest ways to look for the perfect Mytilene getaway is to click on our "All inclusive" filter tool. You can also find other excellent 4-star options such as [Porto Lesvos](https://www.expedia.com/Lesvos-Hotels-Porto-Lesvos.h13234143.Hotel-Information) and [Theofilos Paradise Boutique Hotel](https://www.expedia.com/Lesvos-Hotels-Theofilos-Paradise-Boutique-Hotel.h12319222.Hotel-Information). They both feature outstanding service and a wealth of amenities for your relaxation and comfort. ### Are there any 4-star casino hotels in Mytilene? Use our convenient filters to refine your Mytilene search by star rating, amenities and more. Whether you're after the complete casino resort experience or just want to try your luck while living it up in 4-star style, you're sure to find a place that strikes the perfect balance between entertainment and relaxation. ## Explore a world of travel with Expedia - [Lodging](?equalTargetTab=tab-0) - [Flights](?equalTargetTab=tab-1) - [Packages](?equalTargetTab=tab-2) - [Cars](?equalTargetTab=tab-3) - [Vacation Rentals](?equalTargetTab=tab-4) - [Panagiouda Hotels](https://www.expedia.com/Panagiouda-Hotels.d3000739637.Travel-Guide-Hotels) - [Villas in North Aegean Islands](https://www.expedia.com/North-Aegean-Islands-Villas.d6051354-aaVillas.Travel-Guide-Accommodation) - [Luxury Hotels in Mytilene](https://www.expedia.com/Mytilene-Hotels-Luxury-Hotel.0-0-d6062865-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [North Aegean Islands Hotels](https://www.expedia.com/Destinations-In-North-Aegean-Islands.d6051354.Hotel-Destinations) - [Aparthotels in Panagiouda](https://www.expedia.com/Panagiouda-Apart-Hotels.d3000739637-aaApartHotels.Travel-Guide-Accommodation) - 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[Mytilene Vacations](https://www.expedia.com/Mytilene.d6062865.Destination-Travel-Guides) - [Yeni Mosque](https://www.expedia.com/Yeni-Mosque-Lesvos.d6330372.Vacation-Attraction) - [Roman Aqueduct at Moria](https://www.expedia.com/Roman-Aqueduct-At-Moria-Lesvos.d6330367.Vacation-Attraction) - [Visit Varia](https://www.expedia.com/Varia.dx6322122) - [Olive-Press Museum of Archipelagos Society](https://www.expedia.com/Olive-Press-Museum-Of-Archipelagos-Society-Lesvos.d553248621532502390.Vacation-Attraction) - [Port of Mytilene](https://www.expedia.com/Port-Of-Mytilene-Lesvos.d553248621563225013.Vacation-Attraction) - [Visit Panagiouda](https://www.expedia.com/Panagiouda.dx3000739637) - [Church of Agios Therapon](https://www.expedia.com/Church-Of-Agios-Therapon-Lesvos.d553248621533101623.Vacation-Attraction) - [Theophilos Museum](https://www.expedia.com/Theophilos-Museum-Lesvos.d553248621532502392.Vacation-Attraction) - [North Aegean Islands Vacations](https://www.expedia.com/North-Aegean-Islands.d6051354.Destination-Travel-Guides) - 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