Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Ortygia 4 Star Hotels

See all 130 Hotels in Ortygia
Royal Maniace Hotel

Royal Maniace Hotel

Lungomare di Ortigia,13, Syracuse
4.0 out of 5.0
4.4 out of 5 (299 reviews)
Great location!The hotel was chosen because of the location- overlooking the sea- and it's proximity to the centre of Ortigia. The hotel staff were very pleasant and helpful. The bathroom was tired and could do with come TLC, but everything worked just fine. (It did lack hanging / shelf facilities for towels- which ...
  Dec 28, 2017

$47

$47
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93, Syracuse
4.0 out of 5.0
4.6 out of 5 (322 reviews)
Great Staff and ServiceDuring our stay, we really enjoyed the help of Magdalena at the front desk with restaurant reservations and recommendations, all of which were excellent. It was genuinely great service and a lovely stay at the Algila.
  Jan 5, 2018

$234

$234
Charme Hotel Henry's House

Charme Hotel Henry's House

Via del Castello Maniace n. 68, Syracuse
4.0 out of 5.0
4.8 out of 5 (120 reviews)
Charming hotel with excellent view of the sea.The hotel staff was extremely friendly and helpful. Rooms were different and colorful.
  Jan 5, 2018

$146

$146
Antico Hotel Roma 1880

Antico Hotel Roma 1880

Via Roma 66, Syracuse
4.5 out of 5.0
4.5 out of 5 (268 reviews)
Great locationWe enjoyed walking all over Ortigia. We were close to everything.
  Nov 3, 2017
Hotel Livingston Siracusa

Hotel Livingston Siracusa

Via Nizza, 17, Syracuse
4.5 out of 5.0
4.6 out of 5 (81 reviews)
Beautiful building with great rooms...Excellent facility with great rooms....windows, twelve feet in height, overlooking the Ionian Sea....sunrise was beautiful. I appreciated how the palazzo was respectfully and tastefully renovated....its irregular shapes bring great beauty and grace to this historic structure. The hotel is within ...
  Oct 23, 2017
Ortigia Royal Suite

Ortigia Royal Suite

Via Alagona, 87/89, Ortigia, Syracuse
4.5 out of 5.0
Map

The preparation of any much-needed holiday starts with picking a fantastic location. Ortygia has been a popular destination with tourists because of everything it offers. Location is everything, but that applies to more than the region you are flying into. Now that you have a feel for Ortygia, it is time you to learn a little more about your abode for the next several nights.

Accommodations as Gorgeous as Ortygia

Ortygia saw its fair share of visitors last year. Our review section provides reviews which may help you determine the resort that is the perfect fit for your trip. When you book a 4-star hotel room you can breathe easy knowing that these properties strive to meet your expectations. These hotels strive to make the grounds and facilities pleasing from the time you step onto the property. You won't need to search to sustain your workout routine, enjoy an invigorating dip, or find a nice meal during your stay with all they provide.

Rooms have been configured to keep you as cozy as possible, with amenities like ultra-comfortable bedding, designer bathroom products, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you are need of anything further, you can rest easy the staff will try their best to ensure you continue to be happy during your time. These properties are so lovely that you'll regret the day you have to leave.

Book a 4-Star Hotel in Ortygia Today!

Your vacation to Ortygia should be a complete retreat from your daily routine. With Expedia, you will get inexpensive rates on first-class accommodations to take your getaway to greater heights.

Recently booked 4 Star Hotels in Ortygia

Hotel Gutkowski
3.5 out of 5.0
Last booking: 9 hours ago
Hotel Posta
3.5 out of 5.0
Last booking: 14 hours ago
Palazzo del Sale
0.0 out of 5.0
Last booking: 24 hours ago
Algila' Ortigia Charme Hotel
4.0 out of 5.0
Last booking: 38 hours ago
Antico Hotel Roma 1880
4.5 out of 5.0
Last booking: 45 hours ago