Find 4 Star Hotels in Otay Mesa, CA from $115

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Compare Otay Mesa 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Pendry San Diego

550 J Street, San Diego, CA

$325

$416 total

includes taxes & fees

Apr 21 - Apr 22

9.2/10 Wonderful! (1,002 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Otay Mesa?

We can help you easily track down the perfect 4-star hotel for your vacation in Otay Mesa. Use our filter tool to fine-tune your search by things like budget, conveniences and property star rating and get access to unbeatable deals in a couple of clicks.

Search for the lowest price from $294

What's the difference between 5-star and 4-star hotels in Otay Mesa?

Give yourself the luxury treatment during your Otay Mesa vacation by staying at a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually packed with amenities, including large beds, complimentary bathrobes and plenty more. A 5-star hotel will go the extra mile to make your trip an even more lavish and special one. Round-the-clock concierge assistance, elegant décor and gourmet dining are a few of the first-rate conveniences and services you’ll likely have access to.

Does Otay Mesa have any 4-star all-inclusive resorts?

Finding your dream resort in Otay Mesa is as easy as typing in your travel details and selecting our “All inclusive” filter. Stay and play where everything is already taken care of like your accommodations, meals, activities and entertainment, or opt for a standard 4-star resort in or around this much-loved destination.

Are there any 4-star casino hotels in Otay Mesa?

Use our convenient filter tool to narrow your Otay Mesa search by amenities, star rating and more. Whether you’re after the full gaming resort experience or simply want to give Lady Luck a try while letting your hair down in 4-star style, you’re sure to find something that strikes the ideal balance between relaxation and entertainment.