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Featured Panama 4 Star Hotels

See all 494 Hotels in Panama
Crowne Plaza Panama Airport

Crowne Plaza Panama Airport

Ave. Domingo Diaz, Tocumen
4.0 out of 5.0
4.3 out of 5 (157 reviews)
It's a good hotel close to airport I Hav been staying here before with everything included breakfast lunch n dinner but this time I was charged same price but nothing included that's what was embarrassing
  Sep 6, 2017

$103

$103
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Vía Tocumen, Tocumen
4.0 out of 5.0
3.8 out of 5 (635 reviews)
Very close to the airport. Great attention.Just 2 minutes away from the airport. Great shuttle service. Smooth check in, Very friendly and helpful staff. Highly recommended!
  Sep 18, 2017

$88

$88
Occidental Panamá City

Occidental Panamá City

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
4.0 out of 5.0
4.0 out of 5 (230 reviews)
Perfect hotel in Panama cityEverything perfect, quiet, centrally located. Great service. The staff also allowed to me late check out. Thanks to all
  Sep 24, 2017

$53

$53
Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis

Ave. Balboa al lado de Multicentro, Panama City
4.5 out of 5.0
4.1 out of 5 (741 reviews)
Nice place Excellent location near to everything, good food and the places to have fun are very nice in the floor 62
  Sep 25, 2017

$155

$155
Novotel Panama City

Novotel Panama City

Calle Jose I. Fabrega y Thais de Pons, Panama City
4.0 out of 5.0
4.2 out of 5 (263 reviews)
Nice stayIf you are staying in Panama city for 1 night or more, you wont regret to stay at Novotel. A French franchise hotel, clean, modern and near everything, including the financial district in Panama.
  Sep 20, 2017

$62

$62
RIU Plaza Panama

RIU Plaza Panama

Calle 50, Urb. Marbella, Panama City
4.0 out of 5.0
4.3 out of 5 (494 reviews)
Modern hotelLove this hotel. Very modern and comfortable. We enjoyed it very much :)
  Sep 20, 2017

$91

$91
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Av. Balboa con Calle 53, Panama City
4.0 out of 5.0
4.2 out of 5 (25 reviews)
Nice hotel with super helpful staffsI recently stayed at this hotel for almost a week. The room was very clean! There are tons of selection for breakfast buffet. It was totally worth for the money I spent. The hotel staffs were super nice and friendly. Especially Maxine from concierge who is super awsome on providing all sorts of informations/suggestions ...
  Sep 16, 2017

$97

$97
Courtyard Panama at Multiplaza Mall

Courtyard Panama at Multiplaza Mall

Via Israel Multiplaza Pacific Mall, Panama City
4.0 out of 5.0
4.2 out of 5 (145 reviews)
Clean. Crib bed available. Next to mall to do shopping.
  Sep 24, 2017

$99

$99
Radisson Decapolis Panama City

Radisson Decapolis Panama City

Avenida Balboa Con Multicentro, Panama City
4.0 out of 5.0
4.4 out of 5 (262 reviews)
ExcellentEverything was great! The spa is wanderful! The location is very good!
  Sep 19, 2017

$104

$104
Wyndham Panama Albrook Mall

Wyndham Panama Albrook Mall

Ave. Marginal, Corregimiento de Ancon, Panama City
4.0 out of 5.0
4.4 out of 5 (264 reviews)
Lovely hotel located in Albrook MallI absolutely loved the fact that the hotel was located in the mall. It made things much easier as we went back to the room to drop off some of our shopping. We also had lots of lunch and dinner options, we could have eaten in the mall or from the two restaurants at the hotel. And if we wanted some ...
  Sep 25, 2017

$116

$116
Map

The preparation of any much-needed holiday starts with picking a location. Panama has become a popular option with tourists because it offers so much to do. But, "location, location, location" applies to more than just your destination. When you want a trip that is great from beginning to end, you need the ideal hotel.

Accommodations as Scenic as Panama

Panama saw its fair share of visitors in the last year. Expedia's review section boast tips and tricks which may help you decide which lodge is optimal for your vacation. When you book a 4-star suite you can breathe easy knowing that these properties are designed to meet your needs. These hotels aim to make the facilities and grounds welcoming during your vacation. You won't have to search for to keep up with your exercise routine, an invigorating dip, or nice meal. Panama has dozens of fantastic lodgings that provide the perfect escape.

Rooms have been furnished to keep you as cozy as possible, with amenities like ultra-comfortable bedding, specially designed bathroom products, and in-room coffee or tea. So, sit back and relax. Moreover, if you find yourself in need of anything else, you can trust the staff will work their hardest to ensure you stay pleased during your stay. These accommodations are so nice that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Panama Today!

A getaway to Panama should be one where you don't have to be concerned about the little things. With Expedia, you will get great deals on the best accommodations to take your getaway to greater heights.

Recently booked 4 Star Hotels in Panama

Radisson Summit Hotel and Golf Panama
4.0 out of 5.0
Last booking: 4 minutes ago
RIU Plaza Panama
4.0 out of 5.0
Last booking: 10 minutes ago
Crowne Plaza Panama Airport
4.0 out of 5.0
Last booking: 43 minutes ago
Las Americas Golden Tower Panama
4.0 out of 5.0
Last booking: 57 minutes ago
The Westin Panama
4.0 out of 5.0
Last booking: 1 hour ago
DoubleTree by Hilton Hotel Panama City
4.0 out of 5.0
Last booking: 1 hour ago