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Featured Panama 4 Star Hotels

See all 496 Hotels in Panama
Crowne Plaza Panama Airport

Crowne Plaza Panama Airport

Ave. Domingo Diaz, Tocumen
4.0 out of 5.0
4.3 out of 5 (488 reviews)
Location & staffLocation is ideal !! Staff is fantastic, they even fix disasters created by Expedia !!!
  Nov 20, 2017

$105

$105
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Vía Tocumen, Tocumen
4.0 out of 5.0
4.0 out of 5 (1,807 reviews)
Very nice hotelThis was a very nice hotel. The setting of the outdoor bar, pool and hot tub was beautiful . Very close to airport made it very convenient and helpful with the free shuttle to and from the airport. Definitely recomment this hotel.
  Nov 8, 2017

$92

$92
Novotel Panama City

Novotel Panama City

Calle Jose I. Fabrega y Thais de Pons, Panama City
4.0 out of 5.0
4.3 out of 5 (693 reviews)
Feel relaxed and peace to stay at NovoteLGood hotel to stay at good prices through Expedia . Staff is really cooperative. Cleanliness is good , hotel is right in heart of the town . Rgds
  Nov 16, 2017

$56

$56
Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis

Ave. Balboa al lado de Multicentro, Panama City
4.5 out of 5.0
4.3 out of 5 (2,186 reviews)
Great hotel with great lively ambiance!Always love the exciting feeling you get when you walk into a Hard Rock Hotel. The rooms, service, and decor are awesome and would highly recommend this hotel. It is close to malls, business, and an exercise area on the Cinta Costera. My only negative experience was with the parking. I asked when ...
  Nov 15, 2017

$89

$89
RIU Plaza Panama

RIU Plaza Panama

Calle 50, Urb. Marbella, Panama City
4.0 out of 5.0
4.4 out of 5 (1,485 reviews)
Nice hotel, luxuriousThe staff is very kind since you enter the hotel, very big and comfortable. We have an upgrade room thanks to Expedia VIP , then we have a problem with a water filtration and the hotel with no hesitation change us to a suite very very nice, we really appreciate nothing less to expect with so go hotel ...
  Nov 19, 2017

$85

$85
DoubleTree by Hilton Hotel Panama City

DoubleTree by Hilton Hotel Panama City

Via Espana, Federico Boyd & Bella Vista, Panama City
4.0 out of 5.0
4.1 out of 5 (1,499 reviews)
Upgraded to a better roomThis was our 3rd time at this hotel. Front desk suggested an upgrade which included breakfast buffet (okay but not much selection if you do not eat pork), restaurant discount but not for room service but the highlight was a large soaker bathtub which is not the norm in Panama. The room was a bit ...
  Nov 9, 2017

$60

$60
Courtyard Panama at Multiplaza Mall

Courtyard Panama at Multiplaza Mall

Via Israel Multiplaza Pacific Mall, Panama City
4.0 out of 5.0
4.2 out of 5 (457 reviews)
Nice place, perfectly for shoppingThe hotel is inside the mall, was a comfortable stay and friendly staff.
  Nov 19, 2017

$84

$84
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Av. Balboa con Calle 53, Panama City
4.0 out of 5.0
4.4 out of 5 (101 reviews)
SECOND TIME A CHARMWe stayed here last year and loved the hotel and its location. This year we were greeted by Victor, one of the doormen that remembered us from last year. The food service staff, one morning, was really overworked, but the extraordinary work of the waiter Valerio Morales, saved the day, all while ...
  Nov 6, 2017

$97

$97
Occidental Panamá City

Occidental Panamá City

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
4.0 out of 5.0
4.1 out of 5 (673 reviews)
Nice Hotel & Great Location.I always stay here when in the city, great staff, comfortable room and located around shopping with the metro down the block. The breakfuss is always good.
  Nov 2, 2017

$54

$54
Radisson Decapolis Panama City

Radisson Decapolis Panama City

Avenida Balboa Con Multicentro, Panama City
4.0 out of 5.0
4.4 out of 5 (583 reviews)
Great overnight stayStaff is really helpful and provided excellent service. Great breakfast with lots of choices included with the room. The room was nice but the beds were hard and not very comfortable. The hotel restaurant is very nice and had a great dinner. The hotel has a walkway to a 4 story mall if you want to ...
  Nov 16, 2017

$98

$98
Map

The preparation of any much-needed holiday starts with picking a location. Panama has become a popular option with tourists because it offers so much to do. But, "location, location, location" applies to more than just your destination. When you want a trip that is great from beginning to end, you need the ideal hotel.

Accommodations as Scenic as Panama

Panama saw its fair share of visitors in the last year. Expedia's review section boast tips and tricks which may help you decide which lodge is optimal for your vacation. When you book a 4-star suite you can breathe easy knowing that these properties are designed to meet your needs. These hotels aim to make the facilities and grounds welcoming during your vacation. You won't have to search for to keep up with your exercise routine, an invigorating dip, or nice meal. Panama has dozens of fantastic lodgings that provide the perfect escape.

Rooms have been furnished to keep you as cozy as possible, with amenities like ultra-comfortable bedding, specially designed bathroom products, and in-room coffee or tea. So, sit back and relax. Moreover, if you find yourself in need of anything else, you can trust the staff will work their hardest to ensure you stay pleased during your stay. These accommodations are so nice that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Panama Today!

A getaway to Panama should be one where you don't have to be concerned about the little things. With Expedia, you will get great deals on the best accommodations to take your getaway to greater heights.

Recently booked 4 Star Hotels in Panama

Novotel Panama City
4.0 out of 5.0
Last booking: 4 hours ago
Riande Aeropuerto Hotel & Casino
4.0 out of 5.0
Last booking: 5 hours ago