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Featured Panama 4 Star Hotels

See all 500 Hotels in Panama
Crowne Plaza Panama Airport

Crowne Plaza Panama Airport

Ave. Domingo Diaz, Tocumen
4.0 out of 5.0
4.3 out of 5 (166 reviews)
Best location for the airportI ALWAYS stay here flying in or out of Panama. Literally around the corner from the airport. Shuttle is always on time & great staff !! Hotel ALWAYS treats you like family .... maybe due to me being there so much ! Staff ALWAYS has an English speaking person on duty. Facility is simply GREAT !!! ...
  Oct 23, 2017

$102

$102
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Vía Tocumen, Tocumen
4.0 out of 5.0
3.8 out of 5 (637 reviews)
I like this hotel, the price is good and overall environment is perfect.But the food is not so good, I ordered an stake, it's bad and I only eat a little. The breakfast is also not good.
  Oct 4, 2017

$85

$85
Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis

Ave. Balboa al lado de Multicentro, Panama City
4.5 out of 5.0
4.1 out of 5 (743 reviews)
Nice place Excellent location near to everything, good food and the places to have fun are very nice in the floor 62
  Sep 25, 2017

$120

$120
Occidental Panamá City

Occidental Panamá City

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
4.0 out of 5.0
4.0 out of 5 (238 reviews)
Stunning HotelVery helpful and friendly staff and a very clean hotel.
  Oct 18, 2017

$57

$57
Novotel Panama City

Novotel Panama City

Calle Jose I. Fabrega y Thais de Pons, Panama City
4.0 out of 5.0
4.2 out of 5 (273 reviews)
Fast 1 day business Quite, compact and well maintained up to the date my 7th time there and it is great for the money
  Oct 19, 2017

$60

$60
RIU Plaza Panama

RIU Plaza Panama

Calle 50, Urb. Marbella, Panama City
4.0 out of 5.0
4.2 out of 5 (504 reviews)
The room doesn't has slipper The bed light were not worked. So I could not relax on my bed to check the laptop
  Oct 15, 2017

$85

$85
DoubleTree by Hilton Hotel Panama City

DoubleTree by Hilton Hotel Panama City

Via Espana, Federico Boyd & Bella Vista, Panama City
4.0 out of 5.0
4.0 out of 5 (419 reviews)
Very nice hotelGood location, Excelent Atention. Hotel in good condition, staff is very kind
  Oct 2, 2017

$58

$58
Courtyard Panama at Multiplaza Mall

Courtyard Panama at Multiplaza Mall

Via Israel Multiplaza Pacific Mall, Panama City
4.0 out of 5.0
4.2 out of 5 (150 reviews)
Great locationCheck in was quick. The reception from staff was warm and efficient. Friendly help provided with luggage. Staff were pleasant and helpful throughout the stay. The hotel is conveniently located at a mall that has everything....including Tony Romas.
  Oct 9, 2017

$99

$99
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Av. Balboa con Calle 53, Panama City
4.0 out of 5.0
4.3 out of 5 (29 reviews)
Very nice hotel. Received early check in which was nice and the pool felt great after a travel day
  Oct 22, 2017

$97

$97
Wyndham Panama Albrook Mall

Wyndham Panama Albrook Mall

Ave. Marginal, Corregimiento de Ancon, Panama City
4.0 out of 5.0
4.4 out of 5 (269 reviews)
Great Hotel. Great Location. Great breakfast. It's pretty well located, it's inside Albrook Mall and nearby many touristic places.
  Oct 9, 2017

$83

$83
Map

The preparation of any much-needed holiday starts with picking a location. Panama has become a popular option with tourists because it offers so much to do. But, "location, location, location" applies to more than just your destination. When you want a trip that is great from beginning to end, you need the ideal hotel.

Accommodations as Scenic as Panama

Panama saw its fair share of visitors in the last year. Expedia's review section boast tips and tricks which may help you decide which lodge is optimal for your vacation. When you book a 4-star suite you can breathe easy knowing that these properties are designed to meet your needs. These hotels aim to make the facilities and grounds welcoming during your vacation. You won't have to search for to keep up with your exercise routine, an invigorating dip, or nice meal. Panama has dozens of fantastic lodgings that provide the perfect escape.

Rooms have been furnished to keep you as cozy as possible, with amenities like ultra-comfortable bedding, specially designed bathroom products, and in-room coffee or tea. So, sit back and relax. Moreover, if you find yourself in need of anything else, you can trust the staff will work their hardest to ensure you stay pleased during your stay. These accommodations are so nice that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Panama Today!

A getaway to Panama should be one where you don't have to be concerned about the little things. With Expedia, you will get great deals on the best accommodations to take your getaway to greater heights.

Recently booked 4 Star Hotels in Panama

Radisson Colon 2,000 Hotel & Casino
4.0 out of 5.0
Last booking: 7 minutes ago
Riande Aeropuerto Hotel & Casino
4.0 out of 5.0
Last booking: 12 minutes ago