Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured San Diego County 4 Star Hotels

See all 1,462 Hotels in San Diego County
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

1 Market Pl, San Diego
4.0 out of 5.0
4.5 out of 5 (3,217 reviews)
Location Location Location This hotel is centrally located and is walking distance to multiple points of interests. Great restaurants nearby. We had a room with a beautiful view of the bay.
  Oct 21, 2017

$189

$189
Wyndham San Diego Bayside

Wyndham San Diego Bayside

1355 N Harbor Drive, San Diego
4.0 out of 5.0
3.8 out of 5 (2,615 reviews)
Grate staff assistance, excellent location, comfortable and clean room, free internet and great in room service.
  Oct 21, 2017

$135

$135
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

207 5th Ave, San Diego
4.0 out of 5.0
4.2 out of 5 (1,085 reviews)
Great stay!Room was clean and very roomy, we got a suite. Check in was fast and employees were friendly. Third time we stay here and never has an issue!
  Oct 3, 2017

$179

$179
Hyatt Regency La Jolla

Hyatt Regency La Jolla

3777 La Jolla Village Drive, San Diego
4.0 out of 5.0
4.3 out of 5 (1,003 reviews)
Very nice hotelWe had a good stay. Staff were very courteous and helpful
  Oct 10, 2017

$134

$134
Hilton San Diego Bayfront

Hilton San Diego Bayfront

1 Park Blvd, San Diego
4.0 out of 5.0
4.3 out of 5 (1,893 reviews)
Good hotel, close to water, a walk to the gas lamp, but not too far
  Oct 20, 2017

$134

$134
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

1441 Quivira Rd, San Diego
4.0 out of 5.0
3.8 out of 5 (1,545 reviews)
Beautiful room with million dollar view (in tower)It was outstanding on every way - the room, the hotel, the staff, the restaurant.
  Oct 18, 2017

$123

$123
Sheraton San Diego Hotel and Marina

Sheraton San Diego Hotel and Marina

1380 Harbor Island Dr, San Diego
4.0 out of 5.0
3.9 out of 5 (2,779 reviews)
Across the bay!Great bayside view, large room, excellent service. We had a pleasant, relaxing stay - includes pool and spa.
  Oct 17, 2017

$159

$159
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

601 Pacific Hwy, San Diego
4.0 out of 5.0
4.2 out of 5 (706 reviews)
Very pleased over all. The free Happy hour and breakfast were great. Nice location near the waterfront. Walking distance to USS Midway and cruises. Parking at the hotel cost $50. Staff was friendly. We enjoyed our stay.
  Oct 17, 2017

$169

$169
Paradise Point Resort & Spa

Paradise Point Resort & Spa

1404 Vacation Rd, San Diego
4.0 out of 5.0
3.7 out of 5 (1,183 reviews)
Excellent family vaca location The resort is huge, plenty of pools, beach area and nightly lit fire pits. The rooms are nice enough, but some of our outlets needed replacing and the bathroom reeked of mildew. Great bar service at the Barefoot Bar & Grill onsite! Would definitely recommend for families wanting to see local attractions ...
  Oct 18, 2017

$169

$169
Catamaran Resort and Spa

Catamaran Resort and Spa

3999 Mission Boulevard, San Diego
4.0 out of 5.0
4.2 out of 5 (1,575 reviews)
Great locationVery nice place to spend your vacation. Great views and within walking distance to the beach.
  Oct 18, 2017

$129

$129
Map

The preparation of any much-needed vacation starts with deciding on a spot. San Diego County is a popular destination with tourists because of all its local amenities. Yet, "location, location, location" applies to more than just your destination. When you want to make a holiday especially memorable, it's all about where you sleep after the sun sets.

Properties as Beautiful as San Diego County

San Diego County saw hundreds of travelers in 2016, and our review section features reviews on which property will meet your requirements for a wonderful vacation. The resorts found here strive to make your visit as gratifying as your days checking out San Diego County. These hotels work to make their facilities and grounds welcoming from the second you step onto the property. You won't need to search long to keep up with your exercise routine, enjoy a refreshing plunge, or find a nice lunch during your stay with all that they offer. San Diego County has hundreds of splendid accommodations that make for the ideal holiday.

Rooms have been fashioned to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and specially designed bathroom products. So, sit back and unwind. Moreover, if you find yourself in need of something more, you can trust the staff will do their best to ensure you remain pleased during your stay. These accommodations are so lovely that you'll regret the day you have to return home.

Book a 4-Star Hotel in San Diego County Today!

A vacation to San Diego County should be one where you don't have to worry about the little things. Thanks to our handy review section and info on each property, you can easily select the best hotel for your upcoming holiday to San Diego County.