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Featured San Francisco 4 Star Hotels

See all 509 Hotels in San Francisco
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,811 reviews)
Iconic San Francisco right on Union Square. Close to restaurants, cable cars and Chinatown. It's a post-1906 earthquake building so sounds carry from room to room. But it is so beautiful, that doesn't matter.
  Sep 20, 2017

$245

$245
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,611 reviews)
Hotel Serrano was close to Union Square, big bus pickup and bike rentals. Around 10 minute walk to Chinatown. 15 minute walk to SFMOMA. Room was a little small but I expected that in an older building. However, room was clean and the staff was friendly and helpful.
  Sep 20, 2017

$208

$208
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,354 reviews)
Very nice hotelHotel was very nice, within walking distance to Old Town Sacramento. Great Location to walk around and enjoy.
  Sep 20, 2017

$203

$203
Pullman San Francisco Bay

Pullman San Francisco Bay

223 Twin Dolphin Dr, Redwood City
4.0 out of 5.0
4.2 out of 5 (1,248 reviews)
Amazing hotel and great breakfast and friendly staff
  Sep 20, 2017

$143

$143
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,267 reviews)
Great stayStaff were fantastic and helpful. Restaurant was good and not overpriced. Only negative was that on the Monday morning the only breakfast option was the buffet for $22.50 each, and there is nothing close by to walk to. The reason my review is not 5/5 is because they list a hot tub by the pool, but ...
  Sep 19, 2017

$179

$179
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,752 reviews)
Great but expensive Very clean and very comfortable! Only complaint is regarding the terrible out-of-control homeless situation on nearby streets (hundreds of unfortunate souls). Did not feel safe walking far from hotel. SF is going down the tubes!
  Sep 19, 2017

$194

$194
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,407 reviews)
Great location awesome staff! Nice clean room with everything we needed! I would for sure stay here again. Room didn't have working coffee but there was free coffee in the lobby
  Sep 20, 2017

$161

$161
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,641 reviews)
Nice Stay, Decent ServiceToo long a wait to check in with so many staff working at 8 pm Sunday night. Place was not that busy and 5 people on line waiting to check in. Not a big deal but unnecessary. Also, restaurant staff terrible at breakfast. No service at my table.
  Sep 16, 2017

$199

$199
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
4.0 out of 5.0
3.9 out of 5 (2,969 reviews)
Wonderful timeWhen we were checking in, the clerk asked if we wanted to upgrade to a nicer room as the room we paid for was un renovated and old. Obviously, we were a little apprehensive going into our room. We were pleasantly surprised that the room was actually very nice and the bathroom was very quite updated. ...
  Sep 19, 2017

$236

$236
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,365 reviews)
Great place next to everything Had a great stay while visiting San Francisco. Hotel is clise to Union Square and public transportation. Staff were amazing
  Sep 20, 2017

$229

$229
Map

The get-go of any much-needed vacation starts with picking a fantastic location. San Francisco is a popular local with tourists because of all its local amenities. Location is everything, but that doesn't mean just the area you are flying into. When you want to make your next holiday extra special, it's all about where you lay your head at night.

Hotels as Beautiful as the City

San Francisco saw hundreds of guests this past year, and Expedia's review section contains tips on which property will exceed your requirements for an outstanding vacation. The hotels found here strive to make your visit as gratifying as your evenings spent checking out San Francisco. These hotels strive to make the facilities and grounds pleasing during your vacation. You will never need to go far for a tasty breakfast, to sustain your exercise routine, or a refreshing plunge. San Francisco has hundreds of wonderful lodgings that offer the ideal holiday.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, sit back and decompress. Moreover, if you find that you are need of something else, you can rest easy the staff will work their hardest to ensure you continue to be pleased during your time there. These properties are so lovely that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in San Francisco Today!

A vacation to San Francisco should be one where you won't have to be concerned about the little things. Thanks to Expedia's comment section and info on each lodging, you will have no problem finding the perfect hotel for your next vacation to The Golden Gate City.

Recently booked 4 Star Hotels in San Francisco

InterContinental Mark Hopkins
4.0 out of 5.0
Last booking: 6 minutes ago