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Featured San Francisco 4 Star Hotels

See all 543 Hotels in San Francisco
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.5 out of 5.0
4.0 out of 5 (4,603 reviews)
Nice hotel but in a bad areaReader beware: the hotel itself was nice and cheap, but is in a crime ridden area(google tenderloin sf)
  Feb 20, 2018

$120

$120
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.5 out of 5.0
4.3 out of 5 (6,689 reviews)
Loved my stay at Hotel NikkoHotel is in great location. Easy access to BART station @Powell Street, meaning easy access to entire city!
  Feb 23, 2018

$157

$157
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,596 reviews)
Great hotel for families.We loved this hotel. The location is perfect, near the piers. The decor is fun and creative. My kids loved the in room magnetic dart board and balcony over the courtyard. The courtyard is awesome, fire pits, giant connect four, art and a cute vintage trailer serving drinks and snacks. The staff was ...
  Feb 24, 2018

$159

$159
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.5 out of 5.0
4.2 out of 5 (5,837 reviews)
Good hotel with friendly staffNice clean rooms, friendly staff. Complimentary coffee in morning and water all day. We received two coupons for free Rose wine which was welcome. There are no hotel breakfast facilities but there are many outlets nearby. Good location for Fisherman’s wharf and Union square is a short cable car ride ...
  Feb 24, 2018

$153

$153
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.5 out of 5.0
4.3 out of 5 (3,860 reviews)
Wonderful hotel and staff.Wonder hotel! Stunning roof top bar and lounge with an incredible 360 view of the city!
  Feb 24, 2018

$151

$151
Sheraton Fisherman's Wharf Hotel

Sheraton Fisherman's Wharf Hotel

2500 Mason St, San Francisco
4.5 out of 5.0
3.8 out of 5 (3,986 reviews)
Excellent Hotel near tourist areas ans sea frontWe are returning customers, Sheraton Fisherman's Wharf is our hotel of choice when staying in San Francisco.
  Feb 22, 2018

$159

$159
Stanford Court San Francisco

Stanford Court San Francisco

905 California Street, San Francisco
4.5 out of 5.0
4.1 out of 5 (3,361 reviews)
Nice hotel on Nob HillFast check in. Modern hotel with good gym. Near Mark Hopkins and Fairmont. Pretty expensive parking.
  Feb 24, 2018

$139

$139
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.5 out of 5.0
4.0 out of 5 (3,314 reviews)
Great hotel close to the airportHung out here for half a day waiting for our flight. Ate at the restaurant twice....very nice people working here.
  Feb 24, 2018

$119

$119
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco
4.5 out of 5.0
4.3 out of 5 (3,254 reviews)
Beautiful hotel overlooking the waterI would definitely stay there again. The customer service was superb.
  Feb 24, 2018

$131

$131
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.5 out of 5.0
4.2 out of 5 (4,475 reviews)
St Francis on Union Sq in SFO.From checking by Louis we felt welcome and we're impresses by the gift of "Franco" and the room upgrade. Room was nicely appointed and comfortable. Every hotel employee from doormen to maids were terrific! Thank you!
  Feb 21, 2018

$187

$187

The get-go of any much-needed vacation starts with picking a fantastic location. San Francisco is a popular local with tourists because of all its local amenities. Location is everything, but that doesn't mean just the area you are flying into. When you want to make your next holiday extra special, it's all about where you lay your head at night.

Hotels as Beautiful as the City

San Francisco saw hundreds of guests this past year, and Expedia's review section contains tips on which property will exceed your requirements for an outstanding vacation. The hotels found here strive to make your visit as gratifying as your evenings spent checking out San Francisco. These hotels strive to make the facilities and grounds pleasing during your vacation. You will never need to go far for a tasty breakfast, to sustain your exercise routine, or a refreshing plunge. San Francisco has hundreds of wonderful lodgings that offer the ideal holiday.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, sit back and decompress. Moreover, if you find that you are need of something else, you can rest easy the staff will work their hardest to ensure you continue to be pleased during your time there. These properties are so lovely that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in San Francisco Today!

A vacation to San Francisco should be one where you won't have to be concerned about the little things. Thanks to Expedia's comment section and info on each lodging, you will have no problem finding the perfect hotel for your next vacation to The Golden Gate City.

Recently booked 4 Star Hotels in San Francisco

Courtyard by Marriott Redwood City
3.5 out of 5.0
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Mystic Hotel
4.0 out of 5.0
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Sweden House Hotel
3.0 out of 5.0
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Embassy Suites San Francisco Airport - South San Francisco
3.5 out of 5.0
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Kimpton Buchanan Hotel
4.0 out of 5.0
Last booking: 7 minutes ago
Hyatt Regency San Francisco
4.5 out of 5.0
Last booking: 7 minutes ago
InterContinental Mark Hopkins
4.5 out of 5.0
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Fairmont San Francisco
5.0 out of 5.0
Last booking: 12 minutes ago
SF Plaza Hotel
2.5 out of 5.0
Last booking: 14 minutes ago