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Featured San Francisco 4 Star Hotels

See all 528 Hotels in San Francisco
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (5,572 reviews)
Wonderful stay.Perfect location near Fisherman's Wharf. Everything was spot-on in our stay there.
  Nov 21, 2017

$167

$167
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (6,469 reviews)
Love it here This is our second time at the NIkko in 3 months. Last time was with a client and this time just for us. We love it here. The staff is fantastic, rooms lovely and the valet and concierge, the very best! Thank you !
  Nov 20, 2017

$176

$176
Hilton San Francisco Downtown/Financial District

Hilton San Francisco Downtown/Financial District

750 Kearny St, San Francisco
4.0 out of 5.0
4.0 out of 5 (3,479 reviews)
a quality hotel in the heart of chinatown this is a nice hotel with a very pleasant staff the room I stayed in was very sufficient and clean and quiet this seems to be a quality hotel in the heart of Chinatown within walking distance of many popular spots I would stay again
  Nov 17, 2017

$143

$143
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco
4.0 out of 5.0
4.3 out of 5 (3,474 reviews)
HotelAwesome great stay I would stay again if I have the Chance. Good quality service and great staff
  Nov 21, 2017

$159

$159
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
4.0 out of 5 (4,447 reviews)
A historic gem in a diverse neighborhood.Surprise fees for “urban taxes” of $26+ were laughable. Hotel is actively renovating, which will only enhance its charm. On checkout day hotel was receiving large order of new mattresses. Looking up!
  Nov 19, 2017

$128

$128
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.4 out of 5 (3,746 reviews)
very central - well priced, but nothing special check in / check ou definitely needs improvement, the set up is not very effective and especially the check out takes time because there are always lines. Management really needs to look at improving the process and the present method of cheking in and checking out people - i suggest separate ...
  Nov 22, 2017

$169

$169
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (5,220 reviews)
Great Anniversary LocationThis is a great location. The view in our room was of Union Square. I highly recommend getting this type of room. The room had plenty of space. The shower had a great shower head. Parking was easy but very pricey ~70/night. Remember that when planning.
  Nov 21, 2017

$158

$158
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (4,032 reviews)
Great location, wonderful rooms!We absolutely loved this hotel. It was conveniently located just mins from pier 39 and across the street from the trolley stop to union square! Being from the Bay Area, I have stayed in many SF hotels. The room here was exceptional. King bed, plenty of room to walk around, we had a couch and a desk ...
  Nov 20, 2017

$152

$152
Sheraton Fisherman's Wharf Hotel

Sheraton Fisherman's Wharf Hotel

2500 Mason St, San Francisco
4.0 out of 5.0
3.9 out of 5 (5,405 reviews)
Convenient Close to Pier 39Will definately stay again, walking distance to so many sight-seeing places. Clean, Safe and many local eats near by.
  Nov 21, 2017

$149

$149
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (3,551 reviews)
Everything was great except for the bed, which was a bit hard for my liking.
  Nov 22, 2017

$99

$99
Map

The get-go of any much-needed vacation starts with picking a fantastic location. San Francisco is a popular local with tourists because of all its local amenities. Location is everything, but that doesn't mean just the area you are flying into. When you want to make your next holiday extra special, it's all about where you lay your head at night.

Hotels as Beautiful as the City

San Francisco saw hundreds of guests this past year, and Expedia's review section contains tips on which property will exceed your requirements for an outstanding vacation. The hotels found here strive to make your visit as gratifying as your evenings spent checking out San Francisco. These hotels strive to make the facilities and grounds pleasing during your vacation. You will never need to go far for a tasty breakfast, to sustain your exercise routine, or a refreshing plunge. San Francisco has hundreds of wonderful lodgings that offer the ideal holiday.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, sit back and decompress. Moreover, if you find that you are need of something else, you can rest easy the staff will work their hardest to ensure you continue to be pleased during your time there. These properties are so lovely that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in San Francisco Today!

A vacation to San Francisco should be one where you won't have to be concerned about the little things. Thanks to Expedia's comment section and info on each lodging, you will have no problem finding the perfect hotel for your next vacation to The Golden Gate City.

Recently booked 4 Star Hotels in San Francisco

Hotel Nikko San Francisco
4.0 out of 5.0
Last booking: 30 minutes ago
Pullman San Francisco Bay
4.0 out of 5.0
Last booking: 53 minutes ago
The Westin San Francisco Airport
4.0 out of 5.0
Last booking: 1 hour ago