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Featured San Francisco 4 Star Hotels

See all 525 Hotels in San Francisco
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (5,564 reviews)
Quick check-in. Very clean and comfortable room. Loved to stay at Zoe.
  Nov 19, 2017

$130

$130
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (6,466 reviews)
Nicely RefreshedThe property was refurbished last year and looks great. Consistent top quality service. Even the bellmen are attentive, friendly and helpful.
  Nov 18, 2017

$176

$176
Hilton San Francisco Downtown/Financial District

Hilton San Francisco Downtown/Financial District

750 Kearny St, San Francisco
4.0 out of 5.0
4.0 out of 5 (3,469 reviews)
a quality hotel in the heart of chinatown this is a nice hotel with a very pleasant staff the room I stayed in was very sufficient and clean and quiet this seems to be a quality hotel in the heart of Chinatown within walking distance of many popular spots I would stay again
  Nov 17, 2017

$143

$143
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco
4.0 out of 5.0
4.3 out of 5 (3,460 reviews)
Super nice hotel, very clean, nice view. Great location.
  Nov 17, 2017

$159

$159
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
4.0 out of 5 (4,443 reviews)
Nice boutique hotel, in a very central location in Union Square district!
  Nov 15, 2017

$128

$128
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.4 out of 5 (3,737 reviews)
Good location Very good location. Have a bay view room. Room is not big enough to comfort a toddler, but the view is fantastic.
  Nov 18, 2017

$169

$169
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (5,206 reviews)
Luis let us check in early and gave us a welcome gift to share with our kids. We had a great view overlooking Union Square. Wished there was a jacuzzi to soak in after walking up and down all the hills.
  Nov 18, 2017

$165

$165
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (4,018 reviews)
39th Anniversary Very nice people at every level of our stay. The food for breakfast was way beyond the normal.I have had better once or twice, but was beyond what I expected. I felt very safe and comfortable. Wish they would have had a pool and hot tub,very small detail. The concierge was wonderful.
  Nov 19, 2017

$152

$152
Sheraton Fisherman's Wharf Hotel

Sheraton Fisherman's Wharf Hotel

2500 Mason St, San Francisco
4.0 out of 5.0
3.9 out of 5 (5,391 reviews)
RaceWe stayed here for a Spartan race we did.. Nice Hotel to say at..
  Nov 19, 2017

$159

$159
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (3,544 reviews)
Nice and close to the airportEasy access to the freeway and SFO. Excellent location.
  Nov 19, 2017

$99

$99
Map

The get-go of any much-needed vacation starts with picking a fantastic location. San Francisco is a popular local with tourists because of all its local amenities. Location is everything, but that doesn't mean just the area you are flying into. When you want to make your next holiday extra special, it's all about where you lay your head at night.

Hotels as Beautiful as the City

San Francisco saw hundreds of guests this past year, and Expedia's review section contains tips on which property will exceed your requirements for an outstanding vacation. The hotels found here strive to make your visit as gratifying as your evenings spent checking out San Francisco. These hotels strive to make the facilities and grounds pleasing during your vacation. You will never need to go far for a tasty breakfast, to sustain your exercise routine, or a refreshing plunge. San Francisco has hundreds of wonderful lodgings that offer the ideal holiday.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, sit back and decompress. Moreover, if you find that you are need of something else, you can rest easy the staff will work their hardest to ensure you continue to be pleased during your time there. These properties are so lovely that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in San Francisco Today!

A vacation to San Francisco should be one where you won't have to be concerned about the little things. Thanks to Expedia's comment section and info on each lodging, you will have no problem finding the perfect hotel for your next vacation to The Golden Gate City.

Recently booked 4 Star Hotels in San Francisco

Hilton San Francisco Union Square
4.0 out of 5.0
Last booking: 1 minute ago
Serrano Hotel
4.0 out of 5.0
Last booking: 5 minutes ago