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Featured San Francisco 4 Star Hotels

See all 500 Hotels in San Francisco
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,814 reviews)
A short stat in San Fran CBDWell located across from union square, excellent facilities including fitness centre, quiet rooms and very helpful staff. Highly recommended
  Sep 23, 2017

$245

$245
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,612 reviews)
Nice hotel! This place was absolutely beautiful on the inside and out. We were informed however that they are renovating soon, so everything will look completely different after October. Lovely service as well as location.
  Sep 25, 2017

$228

$228
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,358 reviews)
holidaylovely stay here. Place spotless, doors opened for you, nothing too much trouble. Staff lovely.Ate at hotel , great tasty food. Just had a refurbishment so very modern and clean.We booked when the Tuscan so didn't have to pay the resort?urban tax fee, this $25 a day otherwise now. We visited Alcatraz ...
  Sep 23, 2017

$203

$203
Pullman San Francisco Bay

Pullman San Francisco Bay

223 Twin Dolphin Dr, Redwood City
4.0 out of 5.0
4.2 out of 5 (1,248 reviews)
Amazing hotel and great breakfast and friendly staff
  Sep 20, 2017

$143

$143
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,268 reviews)
ambiance goodWe're happy even it was a short stay, we get to lounge outside the hotel comfortably, less noise, customer service was excellent, friendly staff...thank you Hyatt! !
  Sep 23, 2017

$219

$219
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,753 reviews)
Excellent service great location near everything Will stay again.
  Sep 22, 2017

$194

$194
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,408 reviews)
sometimes employee staff make all the differencei had some billing issues; Sarbi at the hotel took care of them and that made all the difference. Based on her excellent work, i would recommend the hotel.
  Sep 24, 2017

$161

$161
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,642 reviews)
Large modern hotel located centrallyVery efficient hotel where everything worked and staff were helpful. An easy walk to Union Square and most major stores and also near cable car terminus.
  Sep 23, 2017

$199

$199
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
4.0 out of 5.0
3.9 out of 5 (2,969 reviews)
Wonderful timeWhen we were checking in, the clerk asked if we wanted to upgrade to a nicer room as the room we paid for was un renovated and old. Obviously, we were a little apprehensive going into our room. We were pleasantly surprised that the room was actually very nice and the bathroom was very quite updated. ...
  Sep 19, 2017

$236

$236
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,369 reviews)
A great vacationWe had a great stay. It was our first trip to San Francisco. I chose this hotel because of its location and wasn't disappointed. Our room had a view of Union Square and downtown along with the harbor. The staff was great and was able to recommend a couple of things for us to see that we hadn't thought ...
  Sep 24, 2017

$229

$229
Map

The get-go of any much-needed vacation starts with picking a fantastic location. San Francisco is a popular local with tourists because of all its local amenities. Location is everything, but that doesn't mean just the area you are flying into. When you want to make your next holiday extra special, it's all about where you lay your head at night.

Hotels as Beautiful as the City

San Francisco saw hundreds of guests this past year, and Expedia's review section contains tips on which property will exceed your requirements for an outstanding vacation. The hotels found here strive to make your visit as gratifying as your evenings spent checking out San Francisco. These hotels strive to make the facilities and grounds pleasing during your vacation. You will never need to go far for a tasty breakfast, to sustain your exercise routine, or a refreshing plunge. San Francisco has hundreds of wonderful lodgings that offer the ideal holiday.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, sit back and decompress. Moreover, if you find that you are need of something else, you can rest easy the staff will work their hardest to ensure you continue to be pleased during your time there. These properties are so lovely that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in San Francisco Today!

A vacation to San Francisco should be one where you won't have to be concerned about the little things. Thanks to Expedia's comment section and info on each lodging, you will have no problem finding the perfect hotel for your next vacation to The Golden Gate City.

Recently booked 4 Star Hotels in San Francisco

Grand Hyatt San Francisco Union Square
4.0 out of 5.0
Last booking: 4 minutes ago
Orchard Garden Hotel
4.0 out of 5.0
Last booking: 5 minutes ago