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Featured San Francisco 4 Star Hotels

See all 521 Hotels in San Francisco
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,375 reviews)
WONDERFUL EXPERIENCEGREAT HOTEL VERY CLOSE TO FISHERMAN'S WHARF AND PIER 39. HOTEL ZOE HAD VERY UPDATED ROOMS AND THE STAFF KNEW HOW TO DELIVER GREAT SERVICE!
  Oct 17, 2017

$209

$209
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,635 reviews)
valueWell the hotel is in the Tenderloin so ya it's a little rough, but be smart about it. It is just at the edge of the Tenderloin. Make sure to turn left when you leave the hotel or left onto O'farell and it's fine Great places nearby like Liho Liho Yacht Club! Waited at the bar for a spot was insanely ...
  Oct 16, 2017

$178

$178
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,836 reviews)
Excellent hotel for first time in San Francisco as handy for shops and tour bus locations as well as car hire. Came also on recommendation which I would pass on.
  Oct 17, 2017

$249

$249
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,775 reviews)
Nice hotel but over ratedMy stay at this hotel was generally OK but it was very expensive. The service was not good at all. The internet was horrible and extremely slow
  Oct 17, 2017

$232

$232
Hilton San Francisco Downtown/Financial District

Hilton San Francisco Downtown/Financial District

750 Kearny St, San Francisco
4.0 out of 5.0
4.0 out of 5 (1,193 reviews)
Last minute gatewaylast minute change of plans, hotel was convenient in the area we wanted to be. Great front desk people, room service fast, and outstanding. Extremely friendly..........would stay there again...
  Oct 17, 2017

$229

$229
Pullman San Francisco Bay

Pullman San Francisco Bay

223 Twin Dolphin Dr, Redwood City
4.0 out of 5.0
4.2 out of 5 (1,268 reviews)
great place and location very clean loved itgreat place and location very clean loved it. close to everything easy access to freeway.
  Oct 17, 2017

$143

$143
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,657 reviews)
ReviewThe hotel was nicely updated, close to everything.
  Oct 14, 2017

$208

$208
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,386 reviews)
Very nice hotel. Great location too. Check-in was very quick. Front desk person was able to find a nice room facing Union Square for us even though we arrived in the morning. Staff was helpful and friendly at all times. Room service was excellent too.
  Oct 13, 2017

$209

$209
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
4.0 out of 5.0
3.9 out of 5 (2,988 reviews)
CentralClean hotel, nice and helpful staff. Easy check in/check out. Nice lobby bar and good location to the financial district. Lots of choices for food/drinks within walking distance (just avoid the direction towards the Tenderloin as it's really close).
  Oct 17, 2017

$211

$211
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,276 reviews)
Nice vote!Nice hotel friendly staff Near airport,beach,and downtown
  Oct 17, 2017

$149

$149
Map

The get-go of any much-needed vacation starts with picking a fantastic location. San Francisco is a popular local with tourists because of all its local amenities. Location is everything, but that doesn't mean just the area you are flying into. When you want to make your next holiday extra special, it's all about where you lay your head at night.

Hotels as Beautiful as the City

San Francisco saw hundreds of guests this past year, and Expedia's review section contains tips on which property will exceed your requirements for an outstanding vacation. The hotels found here strive to make your visit as gratifying as your evenings spent checking out San Francisco. These hotels strive to make the facilities and grounds pleasing during your vacation. You will never need to go far for a tasty breakfast, to sustain your exercise routine, or a refreshing plunge. San Francisco has hundreds of wonderful lodgings that offer the ideal holiday.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, sit back and decompress. Moreover, if you find that you are need of something else, you can rest easy the staff will work their hardest to ensure you continue to be pleased during your time there. These properties are so lovely that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in San Francisco Today!

A vacation to San Francisco should be one where you won't have to be concerned about the little things. Thanks to Expedia's comment section and info on each lodging, you will have no problem finding the perfect hotel for your next vacation to The Golden Gate City.

Recently booked 4 Star Hotels in San Francisco

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