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Featured San Francisco 4 Star Hotels

See all 521 Hotels in San Francisco
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,372 reviews)
EverythingThe hotel was very convenient to Fisherman's Wharf. The staff was very helpful in making recommendations on eating and what to do.
  Oct 15, 2017

$209

$209
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,635 reviews)
valueWell the hotel is in the Tenderloin so ya it's a little rough, but be smart about it. It is just at the edge of the Tenderloin. Make sure to turn left when you leave the hotel or left onto O'farell and it's fine Great places nearby like Liho Liho Yacht Club! Waited at the bar for a spot was insanely ...
  Oct 16, 2017

$178

$178
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,835 reviews)
Excellent location. Very elegant appearance.Hotel is very well staffed. There's always someone available for any questions. Full Service hotel
  Oct 10, 2017

$249

$249
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,774 reviews)
Stayed for 2 nights nothing to complain about ----
  Oct 16, 2017

$232

$232
Hilton San Francisco Downtown/Financial District

Hilton San Francisco Downtown/Financial District

750 Kearny St, San Francisco
4.0 out of 5.0
4.0 out of 5 (1,193 reviews)
Well located hotelThe quality, knowledge and gentleness of the hotel staff is remarkable. From the concierge to the house keeping the professionalism and gentleness is clearly appreciated. Another asset is the location, walking distance to most of the poi in the city.
  Oct 13, 2017

$229

$229
Pullman San Francisco Bay

Pullman San Francisco Bay

223 Twin Dolphin Dr, Redwood City
4.0 out of 5.0
4.2 out of 5 (1,264 reviews)
Great hotel. Staff very friendly.Hotel is close to the airport. Hotel overlooks beautiful lake and gardens.
  Oct 16, 2017

$143

$143
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,657 reviews)
ReviewThe hotel was nicely updated, close to everything.
  Oct 14, 2017

$208

$208
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,385 reviews)
Very nice hotel. Great location too. Check-in was very quick. Front desk person was able to find a nice room facing Union Square for us even though we arrived in the morning. Staff was helpful and friendly at all times. Room service was excellent too.
  Oct 13, 2017

$209

$209
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
4.0 out of 5.0
3.9 out of 5 (2,986 reviews)
Hilton San Francisco Convenient location. Nice room, but we upgraded. Great bar area on first floor. Concierge was very helpful. Skylounge is amazing. Easy access to BART and could walk to Union Square and Westfield Mall.
  Oct 15, 2017

$211

$211
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,275 reviews)
Airport ServiceExcellent early morning airport shuttle service ... a key factor for us. Also, we had a good dinner at the bistro dining.
  Oct 13, 2017

$149

$149
Map

The get-go of any much-needed vacation starts with picking a fantastic location. San Francisco is a popular local with tourists because of all its local amenities. Location is everything, but that doesn't mean just the area you are flying into. When you want to make your next holiday extra special, it's all about where you lay your head at night.

Hotels as Beautiful as the City

San Francisco saw hundreds of guests this past year, and Expedia's review section contains tips on which property will exceed your requirements for an outstanding vacation. The hotels found here strive to make your visit as gratifying as your evenings spent checking out San Francisco. These hotels strive to make the facilities and grounds pleasing during your vacation. You will never need to go far for a tasty breakfast, to sustain your exercise routine, or a refreshing plunge. San Francisco has hundreds of wonderful lodgings that offer the ideal holiday.

Rooms have been furnished to keep your utmost comfort in mind, with amenities like ultra-comfortable bedding, and in-room coffee or tea, and designer bathroom products. So, sit back and decompress. Moreover, if you find that you are need of something else, you can rest easy the staff will work their hardest to ensure you continue to be pleased during your time there. These properties are so lovely that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in San Francisco Today!

A vacation to San Francisco should be one where you won't have to be concerned about the little things. Thanks to Expedia's comment section and info on each lodging, you will have no problem finding the perfect hotel for your next vacation to The Golden Gate City.

Recently booked 4 Star Hotels in San Francisco

Sheraton Fisherman's Wharf Hotel
4.0 out of 5.0
Last booking: 1 minute ago
W San Francisco
4.0 out of 5.0
Last booking: 1 minute ago
Hotel Nikko San Francisco
4.0 out of 5.0
Last booking: 3 minutes ago
Pullman San Francisco Bay
4.0 out of 5.0
Last booking: 9 minutes ago