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Featured St. Charles 4 Star Hotels

See all 241 Hotels in St. Charles
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis
4.0 out of 5.0
4.3 out of 5 (1,639 reviews)
Beale street Make sure you request the right side of hotel depending on your visit. I was only there overnight to fly in the morning. My room was only a few feet from a band stand and the said band and noise from Beale street played until 2 am. Hotel could not move me.
  Sep 17, 2017

$119

$119
HoteLumiere at the Arch

HoteLumiere at the Arch

999 N. 2nd St., St. Louis
4.0 out of 5.0
2.8 out of 5 (93 reviews)
Had never stayed here before - Got a good deal on a room - was nice to be so close to the casino - would definitely stay here again!
  Sep 20, 2017

$125

$125
The Hotel Majestic St. Louis

The Hotel Majestic St. Louis

1019 Pine St, St. Louis
4.0 out of 5.0
3.9 out of 5 (472 reviews)
Nice hotel close to everythinfHotel is clean, large rooms, decent bathroom, very friendly staff. Within walking distance of MetroLink, Arch, stadium, convention center, and more.
  Sep 19, 2017

$116

$116
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis
4.5 out of 5.0
4.6 out of 5 (908 reviews)
Wonderful locationWe stayed here on our way to Nashville. It was a great stop on the way, right across the street from Bush Stadium, might be crazy on game day but boy would it be handy. It was nice that it was a quiet evening but had a great place to hang out and watch ballgames.
  Sep 17, 2017

$139

$139
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles
4.5 out of 5.0
4.5 out of 5 (301 reviews)
Great hotelNice clean hotel with friendly staff. The only complaint I have us that with all the restaurants downstairs and possible leftover takeout, the rooms have a fridge but no microwaves.
  Sep 16, 2017

$134

$134
Moonrise Hotel

Moonrise Hotel

6177 Delmar Blvd, St. Louis
4.0 out of 5.0
4.7 out of 5 (539 reviews)
Edgy, modern hotel with great amenities!!We had a wonderful weekend in Saint Louis visiting relatives! We arrived very late and were so pleased the restaurant in the hotel was open late and had a great meal. The rooftop bar was an added bonus with a beautiful view of the skyline. Our room was clean and had everything you could want, i.e. ...
  Sep 18, 2017

$179

$179
Marriott St. Louis Grand

Marriott St. Louis Grand

800 Washington Ave, St. Louis
4.0 out of 5.0
4.0 out of 5 (90 reviews)
Nice place Great location...close to convention center, restaurants, shopping, and downtown trolley stops across the street for easy on off site seeing. We where there when the restaurants in the area closed due to potential rioting and the staff did an amazing job of accommodating more patrons than there restaurant ...
  Sep 18, 2017

$123

$123
River City Casino & Hotel

River City Casino & Hotel

777 River City Casino Blvd, St. Louis
4.0 out of 5.0
4.5 out of 5 (251 reviews)
Beautiful Hotel and Casino. Staff excellent. Rod very informative. Did believe from readings there is a pool. Disappointed. Restaurants good and great price.
  Sep 16, 2017

$127

$127
Hilton St. Louis Downtown at the Arch

Hilton St. Louis Downtown at the Arch

400 Olive St, St. Louis
4.0 out of 5.0
4.3 out of 5 (305 reviews)
If you want to rest, do it here!From the moment I walked in the door to the moment I left I was greeted by the nicest employees! Friendly, professional, caring, respectful and fun. Always willing to go the extra mile to make sure I was well cared for. The room was perfect, the bed -and the best pillows in the world - made sleeping ...
  Sep 18, 2017

$143

$143
The Chase Park Plaza Royal Sonesta St. Louis

The Chase Park Plaza Royal Sonesta St. Louis

212 N Kingshighway, St. Louis
4.5 out of 5.0
4.4 out of 5 (619 reviews)
Central LocationGreeted with kindness from the moment we arrived. The valet staff remembered us from our last stay and immediately accommodated our TEXAS sized vehicle. Check in staff were warm and friendly; bellman attentive. Visited two of the restaurants - easy to adjust menu to fit requests. Excellent food & ...
  Sep 11, 2017

$199

$199
Map

The get-go of any trip starts with picking a destination. St. Charles has become a popular local with travelers because it offers so much. Location is everything, but that doesn't mean just the town you are flying into. When you want a journey that is fantastic from start to finish, you need the right accommodation.

Accommodations as Stunning as the City

St. Charles saw its fair share of visitors this past year. Our comment section provides tips on which hotel will fulfill your wishes for a wonderful stay. The hotels found here strive to make your vacation as gratifying as your evenings spent exploring St. Charles. You will never have to search long for a delicious breakfast, to keep up with your exercise routine, or an invigorating spa treatment during your vacation, thanks to everything these hotels provide. They strive to make the facilities and grounds welcoming from the moment you step out of your car and with every step throughout the hotel.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like specially designed bathroom products, premium bedding, and in-room tea or coffee. So, sit back and decompress. Moreover, if you find that you're need of something further, you can be confident the staff will do their best to ensure you remain pleased during your time there. These accommodations are so lovely that you'll regret the day you have to return home.

Book a 4-Star Hotel in St. Charles Today!

Your trip to St. Charles should be one that you'll recollect for years to come, and booking a 4-star hotel can help make those memories fantastic. With Expedia, you can get cheap rates on world-class accommodations to take your getaway to the next level.

Recently booked 4 Star Hotels in St. Charles

Ameristar Casino Resort and Spa
4.5 out of 5.0
Last booking: 2 hours ago