Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured St. Louis 4 Star Hotels

See all 332 Hotels in St. Louis
HoteLumiere at the Arch

HoteLumiere at the Arch

999 N. 2nd St., St. Louis
    4.0 out of 5.0
     
     
    3.2 out of 5 (575 reviews)
    Staff was Very nice. Asked for a room change with our check in & it was done on the spot. Check in/ out was simple & easy. Would go again. .
    Apr 19, 2018

    HoteLumiere at the Arch$96

    HoteLumiere at the Arch$96
    Hyatt Regency St. Louis at The Arch

    Hyatt Regency St. Louis at The Arch

    315 Chestnut St, St. Louis
      4.0 out of 5.0
       
       
      4.3 out of 5 (5,158 reviews)
      Stay at the Hyatt Regency St. LouisStay was excellent. Facility and staff were top drawer. Room had a fantastic view of the arch. The place was clean as could be and perfectly arranged. Only drawback is parking. $29 per day for St. Louis is a bit outrageous! But, room was superior
      Apr 18, 2018

      Hyatt Regency St. Louis at The Arch$109

      Hyatt Regency St. Louis at The Arch$109
      The Hotel Majestic St. Louis

      The Hotel Majestic St. Louis

      1019 Pine St, St. Louis
        4.0 out of 5.0
         
         
        3.7 out of 5 (1,223 reviews)
        Very nice older hotel - hidden gem in St LouisFirst of all, you must understand that we are talking St Louis, so most of the hotels are either casinos, luxury, or historical. We chose the Majestic because we wanted a quieter stay during the convention. We were only about 5 blocks away from the convention center. Had the option of city parking ...
        Apr 4, 2018

        The Hotel Majestic St. Louis$113

        The Hotel Majestic St. Louis$113
        The Chase Park Plaza Royal Sonesta St. Louis

        The Chase Park Plaza Royal Sonesta St. Louis

        212 N Kingshighway, St. Louis
          4.5 out of 5.0
           
           
          4.4 out of 5 (1,687 reviews)
          Great location and a classicI love the Chase and stay here often. I was sorry to see the amenities slip just a bit. Minor to be sure, but in my pet peeve circle: one cup coffee makers with powdered creamer— ugh. At least offer Liquid creamers. It didn’t appear the floor had been vacuumed and the toilet was not made for a tall ...
          Apr 15, 2018

          The Chase Park Plaza Royal Sonesta St. Louis$142

          The Chase Park Plaza Royal Sonesta St. Louis$142
          Hilton St. Louis Downtown at the Arch

          Hilton St. Louis Downtown at the Arch

          400 Olive St, St. Louis
            4.0 out of 5.0
             
             
            4.3 out of 5 (1,296 reviews)
            Great downtown location! Just 2 blocks from the Arch and the Old Courthouse. Easy walking to restaurants and bars.
            Mar 23, 2018

            Hilton St. Louis Downtown at the Arch$124

            Hilton St. Louis Downtown at the Arch$124
            The Westin St. Louis

            The Westin St. Louis

            811 Spruce St, St. Louis
              4.5 out of 5.0
               
               
              4.6 out of 5 (3,258 reviews)
              Clean and nice hotel. Right by the ball park. It is in a great location
              Apr 16, 2018

              The Westin St. Louis$129

              The Westin St. Louis$129
              Moonrise Hotel

              Moonrise Hotel

              6177 Delmar Blvd, St. Louis
                4.0 out of 5.0
                 
                 
                4.7 out of 5 (1,678 reviews)
                Cool hotelTotally different hotel. Loved it! The moon was the theme.
                Apr 18, 2018

                Moonrise Hotel$148

                Moonrise Hotel$148
                Ameristar Casino Resort and Spa

                Ameristar Casino Resort and Spa

                1 Ameristar Blvd, St. Charles
                  4.5 out of 5.0
                   
                   
                  4.5 out of 5 (1,111 reviews)
                  Nice large clean room. Only negative thing was there were no snack machines to use in middle of the night
                  Apr 18, 2018

                  Ameristar Casino Resort and Spa$127

                  Ameristar Casino Resort and Spa$127
                  The Cheshire

                  The Cheshire

                  6300 Clayton Rd, Richmond Heights
                    4.0 out of 5.0
                     
                     
                    4.2 out of 5 (1,433 reviews)
                    English InnHotel on busy road but our room was away from the street so more quiet. Down comforter, nice beds and sheets but bathrooms are a little dated. Keurig coffee in room. Good continental breakfast with fresh fruit and pastries.
                    Apr 13, 2018

                    The Cheshire$135

                    The Cheshire$135
                    Renaissance St. Louis Airport Hotel

                    Renaissance St. Louis Airport Hotel

                    9801 Natural Bridge Road, Berkeley
                      4.0 out of 5.0
                       
                       
                      4.2 out of 5 (1,285 reviews)
                      Very hotel by the airportWe got to the hotel early, and our room was not ready but they offered us another room with a rollaway bed for our daughter. Very convenient, the breakfast buffet was good
                      Mar 23, 2018

                      Renaissance St. Louis Airport Hotel$87

                      Renaissance St. Louis Airport Hotel$87

                      The outset of any much-needed trip kicks off with selecting a location. St. Louis has been a popular option with guests because of everything it offers. Yet, "location, location, location" applies to more than just your vacation destination. Now that you have gotten a feel for St. Louis, it is time you to learn a little more about your residence for the next few nights.

                      Accommodations as Picturesque as St. Louis

                      St. Louis saw hundreds of visitors just last year, and our comment section includes tips and tricks to help you select which room is ideal for your holiday. When you reserve a 4-star hotel you can rest easy knowing that these properties are designed to fulfill your needs. These hotels strive to make the facilities and grounds inviting from the moment you step out of your car. You won't have to search for an energizing plunge, delectable dinner, or to sustain your workout schedule during your stay with all that they offer. St. Louis has hundreds of fantastic lodgings that provide the ideal holiday.

                      Rooms have been furnished to keep you as comfortable as possible, with amenities like designer bathroom products, ultra-comfortable bedding, and in-room tea or coffee. So, lay back and relax. Moreover, if you find yourself in need of something else, you can trust the staff will try their hardest to ensure you stay satisfied during your stay there. These properties are so nice that you'll regret the day you have to fly back home.

                      Reserve a 4-Star Hotel in St. Louis Today!

                      Your trip to St. Louis should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are nothing but fabulous. Thanks to Expedia's comment section and information about each accommodation, you can easily select the right hotel for your next holiday to The Gateway to the West.

                      Recently booked 4 Star Hotels in St. Louis

                      Embassy Suites St. Louis - Downtown
                      3.5 out of 5.0
                      Last booking: 1 minute ago
                      City Place St. Louis - Downtown Hotel
                      3.5 out of 5.0
                      Last booking: 2 minutes ago
                      Drury Inn & Suites Southwest St. Louis
                      3.0 out of 5.0
                      Last booking: 8 minutes ago
                      Drury Inn Airport - St. Louis, MO
                      3.0 out of 5.0
                      Last booking: 11 minutes ago
                      Drury Plaza Hotel St. Louis Chesterfield
                      3.0 out of 5.0
                      Last booking: 16 minutes ago
                      Hyatt Regency St. Louis at The Arch
                      4.0 out of 5.0
                      Last booking: 20 minutes ago
                      Holiday Inn Express & Suites St Louis Airport
                      2.5 out of 5.0
                      Last booking: 20 minutes ago
                      St. Louis Union Station Hotel, Curio Collection by Hilton
                      4.0 out of 5.0
                      Last booking: 31 minutes ago
                      Holiday Inn Express St. Louis Airport - Riverport
                      3.0 out of 5.0
                      Last booking: 36 minutes ago