Title: The Best 5 Star Hotels in Alachua, FL from $104 | Expedia.com

[Alachua Travel Guide](https://expedia.com/Alachua.dx5933)[Hotels in Alachua](https://expedia.com/Alachua-Hotels.d5933.Travel-Guide-Hotels)[Vacation Rentals in Alachua](https://expedia.com/Alachua-Vacation-Rentals.d5933.Travel-Guide-VacationRentals)[Flights to Alachua](https://expedia.com/Cheap-Flights-To-Alachua.d5933.Travel-Guide-Flights)[Car Rentals in Alachua](https://expedia.com/Car-Rentals-In-Alachua.d5933.Car-Rental-Guide)[Alachua Vacation Packages](https://expedia.com/Alachua.d5933.Destination-Travel-Guides)

![Hay Bales and Farmland in Alachua County, Florida](https://images.trvl-media.com/place/5933/116bcdb7-bfde-4b62-8799-00afcb99886b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Alachua 5 Star Hotels

Tonight

[Feb 9 - Feb 10](https://www.expedia.com/Hotel-Search?regionId=5933&startDate=2026-02-09&endDate=2026-02-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 10 - Feb 11](https://www.expedia.com/Hotel-Search?regionId=5933&startDate=2026-02-10&endDate=2026-02-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=5933&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=5933&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Alachua.

![DoubleTree by Hilton Gainesville](https://images.trvl-media.com/lodging/1000000/50000/49700/49617/ff7eaa86_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### DoubleTree by Hilton Gainesville

3726 Sw 40th Blvd Gainesville FL

$93 nightly

$104 total

Feb 16 - Feb 17

Total with taxes and fees

7.8/10 Good! (1,004 reviews)

[](https://expedia.com/Gainesville-Hotels-DoubleTree-By-Hilton-Gainesville.h49617.Hotel-Information)

![Landing Apartments Newberry](https://images.trvl-media.com/lodging/112000000/111070000/111068900/111068878/fde9d20d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Landing Apartments Newberry

120 NW 148th Terrace Newberry FL

$234 nightly

$264 total

Feb 17 - Feb 18

Total with taxes and fees

9.8/10 Exceptional! (48 reviews)

[](https://expedia.com/Newberry-Hotels-Barsala-At-The-Vanguard-Apartments.h111068878.Hotel-Information)

![ Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar](https://images.trvl-media.com/lodging/113000000/112030000/112021600/112021506/83b7eb2e_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

###  Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar

2548 SW 13th St Gainesville FL

$239 nightly

$269 total

Feb 10 - Feb 11

Total with taxes and fees

8.4/10 Very Good! (9 reviews)

[](https://expedia.com/Gainesville-Hotels-The-Scholar.h112021506.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Alachua.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F10%2F2026&endDate=2%2F11%2F2026&regionId=5933&star=50)

You can also use these popular filters to refine your search.

[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F10%2F2026&endDate=2%2F11%2F2026&regionId=5933&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F10%2F2026&endDate=2%2F11%2F2026&regionId=5933&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F10%2F2026&endDate=2%2F11%2F2026&regionId=5933&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F10%2F2026&endDate=2%2F11%2F2026&regionId=5933&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F10%2F2026&endDate=2%2F11%2F2026&regionId=5933&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Alachua

Lace up your hiking boots and explore the natural wonders of Mill Creek Preserve's winding trails. After your outdoor adventure, unwind at the City of Alachua Recreation Center or browse local treasures at the Alachua Library Branch.

[See all hotels in Alachua](https://www.expedia.com/Hotel-Search?startDate=2026-02-23&endDate=2026-02-24&adults=2&regionId=5933)

![Hay Bales and Farmland in Alachua County, Florida](https://images.trvl-media.com/place/5933/116bcdb7-bfde-4b62-8799-00afcb99886b.jpg?impolicy=fcrop&w=900&h=370&p=1&q=high)

## Top Alachua Hotel Reviews

## Find out more about Alachua

Pamper your every whim on your upcoming escape. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Alachua so popular in the last year. There's no reason to delay a getaway to Alachua any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Book one of Expedia's luxurious 5-star hotels in Alachua and get ready to enjoy the getaway of a lifetime. Don't wait any longer!

### Book the Best Alachua 5-Star Hotels

A stay in one of these hotels is bound to be special. Top-notch customer care, luxurious bedding, and fabulous spa offerings are all on offer. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What creature comforts do you want in your lodging? A rejuvenating facial treatment to help your cares fall away? A concierge to help you suggest the next attraction to visit? Beautiful furniture, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Alachua are the perfect place to relax after an exciting day.

### Make Your Escape

The results are in, and Alachua 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Select one of our Alachua 5-star hotels today and decompress in total tranquility tomorrow.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Alachua?

> - Search for the lowest price per night from $104

### What makes a hotel 5 stars in Alachua?

### Are there any 5-star all-inclusive resorts in Alachua?

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