Find 5 Star Hotels in Downtown San Francisco, CA from $130

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Compare Downtown San Francisco 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Downtown San Francisco.
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco, CA
The price is $199 per night from Apr 28 to Apr 29
$199
$273 total
includes taxes & fees
Apr 28 - Apr 29
8.8/10 Excellent! (1,850 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You enjoy the finer things in life, both at home and on vacation. Why not demand total luxury during your jaunt to Downtown San Francisco? There's no reason to delay a getaway to Downtown San Francisco any longer. In fact, the sheer number of visitors to Downtown San Francisco has swelled during the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Downtown San Francisco and get ready to be pampered like never before.

5-Star Hotels in Downtown San Francisco

You'll have a fantastic time at one of these 5-star hotels. Michelin-starred restaurants, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you pick out your next adventure? A deep-tissue massage to help your cares fall away? Beautiful furniture, delectable chocolate desserts, and even a hot tub in the bathroom...these hotels are one-of-a-kind.

Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Downtown San Francisco are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and Downtown San Francisco 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. This is a great time to find 5-star hotel deals in @region! Don't put off your dream vacation any longer. Select one of the 5-star hotels in Downtown San Francisco today and soothe yourself in the lap of luxury tomorrow.

Frequently asked questions

What are the best 5-star hotels in Downtown San Francisco?
Get the indulgent experience at Four Seasons Hotel San Francisco, Taj Campton Place and The St. Regis San Francisco. These are some of the 5-star stays around the San Francisco neighborhood of Downtown San Francisco that are rated highest by our guests.
How much does it cost to stay in a 5-star hotel in Downtown San Francisco?
How much you pay for a 5-star hotel in Downtown San Francisco depends on things such as when you plan to travel and the length of your break. Our insider tip for landing the best deal? Use our pricing filters to check out all of the available options for your preferred dates.

  • Search for the lowest price per night from $130

What makes a hotel 5 stars in Downtown San Francisco?
In Downtown San Francisco, a hotel must provide a specific amount of upscale amenities to earn 5 stars. These may include on-site gyms, saunas and spas, gourmet restaurants, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their extraordinary standard of service. You’ll enjoy things like nightly turn-down services, concierge services and in-room massages. Some may even offer extra touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Downtown San Francisco?
Use our filters to find an upmarket getaway in Downtown San Francisco where everything you need is included. Next, refine your results for properties that have a 5-star rating and are described as “All inclusive.” The main thing on the to-do list at these stays? Pure relaxation and indulgence.
What are the top 5-star spa hotels in Downtown San Francisco?
Enjoy access to various spa treatments and rejuvenating therapies at 1 Hotel San Francisco. Alternatively, prioritize your well-being and put yourself first at Fairmont San Francisco or Four Seasons Hotel San Francisco. These luxurious 5-star spa retreats are located in or near Downtown San Francisco.
Are there any 5-star vacation rentals in Downtown San Francisco?
Our site doesn’t offer any 5-star vacation rentals in Downtown San Francisco. However, you can still find some top-rated properties where the only item on your agenda will be to kick back and have fun. Discover what’s available by checking out our vacation rentals in Downtown San Francisco.

Recent reviews of Downtown San Francisco hotels
Expedia verified reviews

Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5/5 Excellent
"Literally the best hotel I’ve ever stayed at! It’s super clean, nice, classy, and the staff was so sweet! I wish our stay had been longer! I can’t wait to go back! "
A verified traveler stayed at Palace Hotel, a Luxury Collection Hotel, San Francisco
Posted 7 days ago
Palace Hotel, a Luxury Collection Hotel, San Francisco