An aerial view of a coastal town with clear blue waters, a marina, and a long pier extending into the sea.

Find 5 Star Hotels in Duck Key, FL from $232

Check availability on Duck Key 5 Star Hotels

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Oct 14 - Oct 15
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Our top choices for Duck Key 5-star hotels

An aerial view of a resort with a central pool, multiple buildings, and a beach area with sun loungers.
A bar area with wooden chairs, a bar counter, and a variety of bottles and glasses.
A beach scene with two white chairs, a hammock, and palm trees.
A beach with white chairs and kayaks, palm trees, and a clear view of the ocean.

1. Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
Marathon
United States
Clinton
$283 nightly
$318 total
Oct 18 - Oct 19
Total with taxes and fees
Isla Bella Beach Resort & Spa
A resort pool with a view of the sea, surrounded by palm trees and lounge chairs.
A wooden deck with a spiral staircase leading to an upper level.
A modern kitchen with white cabinetry, a marble island, and wooden bar stools.
A clean, empty garage with fluorescent lighting, a metal garage door, and visible plumbing on the ceiling.

2. Sea Glass Cove

Sea Glass Cove
Marathon
Sea Glass Cove
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Duck Key.
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd Marathon FL
$272 nightly
$304 total
Oct 21 - Oct 22
Total with taxes and fees
Hawks Cay Resort
Amara Cay Resort

Amara Cay Resort

80001 Overseas Hwy Islamorada FL
$206 nightly
$232 total
Oct 18 - Oct 19
Total with taxes and fees
8.8/10 Excellent! (1,324 reviews)
Amara Cay Resort
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy Marathon FL
$286 nightly
$322 total
Oct 19 - Oct 20
Total with taxes and fees
8.8/10 Excellent! (1,000 reviews)
Tranquility Bay Beachfront Hotel and Resort
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Duck Key

Kayak through mangrove tunnels and spot colorful fish in the crystal-clear waters surrounding this tiny island paradise. Unwind at Hawks Cay Resort's saltwater lagoon or take a short trip to Marathon for the Turtle Hospital's educational tours.

See all hotels in Duck Key
A coastal city with a long bridge connecting to an island, surrounded by clear blue waters and numerous boats.

Top Duck Key Hotel Reviews

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

10/10 Excellent
"Resort is beautiful, not too big or too small. Room was spectacular. Dinner was great, breakfast was ok. Will definetly be back."
Cristian 1-night trip
Posted 1 day ago
Isla Bella Beach Resort & Spa

Find out more about Duck Key

Ready to experience the next standard in luxury? We know you're thinking about it. Add even more enjoyment on your next trip to Duck Key by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to Duck Key any longer. You'll join the multitudes of vacationers who have made Duck Key so fashionable in the last year. The accommodations in Duck Key also offer great customer service, averaging 3.9 in our ranking system, setting you up for a truly relaxing getaway. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Duck Key and get ready to enjoy the getaway of a lifetime.

5-Star Hotels in Duck Key

You can expect high quality from your hotel. Exceptional customer care, spacious rooms, and fabulous spa offerings are all on offer. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Duck Key offer great customer service, averaging 3.9 in our ranking system, giving you a lot to look forward to. How do you want to relax? 24-hour room service, so you can order that chocolate soufflé© in the wee hours of the morning? A mud wrap treatment that will leave you feeling refreshed and alive? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Then explore the 216 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Duck Key are waiting for you to relax after a busy day.

Your Getaway Starts Today

The results are in, and Duck Key 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Decide on one of the 5-star hotels in Duck Key today and relax in luxe surroundings when you're ready.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Duck Key?
The amount you pay for a 5-star hotel in Duck Key depends on things such as when you want to go and the length of your escape. An insider tip for landing the best deal? Use our pricing filters to check out all of the available options for your selected dates.
  • Search for the lowest price per night from $232
What makes a hotel 5 stars in Duck Key?
Faultless guest service is integral to every 5-star hotel in Duck Key. From the moment you enter the lobby, staff attend to your every need, whether offering luggage assistance and storage or providing a nightly turn-down service. Also, hotels must feature superior amenities to be eligible for a 5-star rating. These can include luxury toiletries, a wellness center, swimming pools, fine dining restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Duck Key?
Use Expedia's filters to find an upscale retreat in Duck Key where most of what you need is included. Next, refine your results for properties that have a 5-star rating and are listed as "All inclusive." The most important thing on the to-do list at these stays? Pure enjoyment and indulgence.

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