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Featured Mendoza Wine Region 5 Star Hotels

See all 237 Hotels in Mendoza Wine Region
Park Hyatt Mendoza

Park Hyatt Mendoza

Chile 1124, Mendoza
5.0 out of 5.0
4.6 out of 5 (717 reviews)
Great hotel! The hotel was very clean and nice. Great location next to great restaurants and bars.
  Dec 10, 2017

$119

$119
Sheraton Mendoza Hotel

Sheraton Mendoza Hotel

Primitivo De La Reta 989, Mendoza
5.0 out of 5.0
4.3 out of 5 (216 reviews)
Staff were friendly and helpful. It was also nice to find a full breakfast available early in the morning that suited my schedule
  Oct 25, 2017

$129

$129
Auberge du Vin, a Tribute Portfolio Hotel, Tupungato

Auberge du Vin, a Tribute Portfolio Hotel, Tupungato

Calle la Costa s/n, Tupungato
5.0 out of 5.0
4.1 out of 5 (55 reviews)
Hotel in the middle of no whereLiked the hotel but not the location. Too far away from things to do.
  Nov 20, 2016

$120

$120
InterContinental Mendoza

InterContinental Mendoza

Blvd. Pérez Cuesta esq. Av Acceso Este, Guaymallen
5.0 out of 5.0
4.3 out of 5 (181 reviews)
Modern hotel next door to a mall Excellent stay, the only complaint was that in the first night they did not have an outlet converter for us at checking, they claimed the hotel was full, we got it the second day, otherwise everything else was excellent, there is a huge kids place across the street, bigger than a chukee cheese that ...
  Jan 5, 2016

$90

$90
Entre Cielos

Entre Cielos

Guardia Vieja 1998, Vistalba, Lujan de Cuyo
5.0 out of 5.0
4.8 out of 5 (41 reviews)
Great stay in Mendoza areaVery friendly staff, excellent restaurant. Very modern architecture and decor, in a great location.
  Aug 12, 2015

$384

$384
Casa de Uco Vineyards & Wine Hotel

Casa de Uco Vineyards & Wine Hotel

Route 94, kilometer 14.5, Tunuyan
5.0 out of 5.0
4.9 out of 5 (33 reviews)
Great hotel in the Uco ValleyBeautifully designed hotel in the Uco Valley. Great rooms. Views of vineyards and Andes are amazing. Peaceful and tranquil. Hotel staff also very thoughtful.
  Aug 24, 2017

$400

$400
Map

There's nothing wrong with enjoying the finer things in life. Why not demand total luxury during your jaunt to Mendoza Wine Region? There's no reason to delay a getaway to Mendoza Wine Region any longer. You'll join the multitudes of vacationers who have made Mendoza Wine Region so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Our 5-star hotels in Mendoza Wine Region are the perfect places to relax in when you really need to escape.

Book the Best Mendoza Wine Region 5-Star Hotels

You'll have a wonderful time at one of these 5-star hotels. Excellent customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A reflexology treatment that will leave you feeling refreshed and alive? Butler services? No matter what you want on a perfect getaway, you're bound to find it here.

But you aren't going to spend your entire vacation in your room, of course. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Mendoza Wine Region are the perfect place to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and Mendoza Wine Region 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. It's time to indulge yourself. Choose one of Expedia's Mendoza Wine Region 5-star hotels today and soothe yourself in total tranquility tomorrow.

Recently booked 5 Star Hotels in Mendoza Wine Region

Sheraton Mendoza Hotel
5.0 out of 5.0
Last booking: 1 hour ago
Park Hyatt Mendoza
5.0 out of 5.0
Last booking: 4 hours ago
Raices Aconcagua Mendoza
4.5 out of 5.0
Last booking: 5 hours ago
Apartamentos Mendoza Premium
3.5 out of 5.0
Last booking: 8 hours ago
Diplomatic Hotel
4.5 out of 5.0
Last booking: 9 hours ago
Auberge du Vin, a Tribute Portfolio Hotel, Tupungato
5.0 out of 5.0
Last booking: 17 hours ago
Villaggio Hotel
4.5 out of 5.0
Last booking: 41 hours ago